Table 1 Potential influencing factors and occurrence of PONV
Potential influencing factor | PONV | Non-PONV | P value |
|---|---|---|---|
No. of patients | 46 | 68 | |
Preoperative | |||
Age (years) | 31.1 ± 7.1 | 33.8 ± 7.5 | 0.056 |
Sex(Male/Female) | 7/39 | 26/42 | 0.012 |
Smoking history(yes/no) | 4/42 | 11/57 | 0.246 |
BMI(kg/m2) | 36.2(32.8, 39) | 36.4(33, 39) | 0.171 |
ASA Physical Status(II/III) | 35/11 | 41/27 | 0.079 |
Comorbidity | |||
-Hypertension(yes/no) | 32/14 | 52/16 | 0.411 |
-Diabetes(yes/no) | 33/13 | 50/18 | 0.833 |
-Obstructive sleep apnea syndrome (yes/no) | 7/39 | 17/51 | 0.209 |
-Arrhythmias(yes/no) | 0/46 | 4/64 | 0.094 |
-Anemia(yes/no) | 0/46 | 2/66 | 0.241 |
Intraoperative | |||
Duration of surgery ≥ 120 min(yes/no) | 23/23 | 20/48 | 0.026 |
Infusion volume(ml/kg) | 13.1(10.9, 14.9) | 12.8(10.3, 15.2) | 0.797 |
Type of anesthesia (Inhalation anesthesia/Total intravenous anesthesia) | 41/5 | 49/19 | 0.028 |
Intraoperative hemodynamic fluctuations | |||
-Hypotension(yes/no) | 6/40 | 8/60 | 0.838 |
-Hypertension(yes/no) | 8/38 | 20/48 | 0.144 |
-Tachycardia(yes/no) | 2/44 | 2/66 | 0.689 |
-Bradycardia(yes/no) | 5/41 | 9/59 | 0.706 |
Types of antiemetic drugs(None/One drug/Two or more drugs) | 0/22/24 | 0/20/48 | 0.046 |
Combined with anticholinergic drugs(yes/no) | 8/38 | 16/52 | 0.430 |
Combined with dexmedetomidine(yes/no) | 20/26 | 29/39 | 0.930 |
Postoperative | |||
Combined with opioid drugs(yes/no) | 20/26 | 38/30 | 0.194 |