Table 1 The baseline characteristics of all patients
Characteristics | Low LAR (N = 4955) | High LAR (N = 3532) | P value |
|---|---|---|---|
Age, years old | 74.3 ± 11.7 | 74.8 ± 11.9 | 0.096 |
Gender, male, n (%) | 2901 (58.5) | 2074 (58.7) | 0.873 |
Weight, kg | 82.6 ± 24.5 | 82.0 ± 23.5 | 0.232 |
Comorbidities, n (%) | |||
Myocardial infarction | 1219 (24.6) | 875 (24.8) | 0.856 |
Congestive heart failure | 2534 (51.1) | 1812 (51.3) | 0.883 |
Hypertension | 2101 (42.4) | 1250 (35.4) | < 0.001 |
Diabetes | 1679 (33.9) | 1242 (35.2) | 0.221 |
Chronic kidney disease | 1511 (30.5) | 1153 (32.6) | 0.035 |
Charlson comorbidity index, points | 6.8 ± 2.5 | 7.3 ± 2.6 | < 0.001 |
Drugs usage, n (%) | |||
βblockers | 4265 (86.1) | 2913 (82.5) | < 0.001 |
Statins | 2979 (60.1) | 1748 (49.5) | < 0.001 |
Aspirin | 3543 (71.5) | 2087 (59.1) | < 0.001 |
Interventions, n (%) | |||
Mechanical ventilation | 2861 (57.7) | 1846 (52.3) | < 0.001 |
Vasopressors | 2576 (52.0) | 1894 (53.6) | 0.137 |
Score system, points | |||
SOFA | 5.8 ± 2.5 | 7.0 ± 2.8 | < 0.001 |
OASIS | 33.4 ± 8.9 | 36.7 ± 9.8 | < 0.001 |
APSIII | 50.7 ± 23.0 | 62.3 ± 27.3 | < 0.001 |
SAPSII | 40.1 ± 12.6 | 44.8 ± 14.2 | < 0.001 |
Vital signs | |||
Mean arterial pressure, mmHg | 81.3 ± 18.5 | 80.6 ± 18.9 | 0.062 |
Heart rate, bpm | 87.3 ± 20.9 | 93.8 ± 23.4 | < 0.001 |
Laboratory values | |||
White blood cell, × 109/L | 10.7 ± 3.5 | 12.7 ± 4.7 | < 0.001 |
Hemoglobin, g/dL | 11.2 ± 2.3 | 10.8 ± 2.3 | < 0.001 |
Platelet, × 109/L | 211.9 ± 97.1 | 211.2 ± 98.9 | 0.776 |
Albumin, g/dL | 3.5 ± 0.6 | 3.0 ± 0.6 | < 0.001 |
Lactate, | 1.2 ± 0.3 | 2.4 ± 1.3 | < 0.001 |
LAR | 0.34 ± 0.09 | 0.82 ± 0.24 | < 0.001 |
Creatinine, mg/dL | 1.1 ± 0.3 | 2.2 ± 0.8 | < 0.001 |
Bicarbonate, | 24.5 ± 4.7 | 23.1 ± 4.9 | < 0.001 |
Outcomes | |||
Length of ICU stay | 2.6 (1.4, 5.1) | 3.2 (1.7, 6.7) | < 0.001 |
Length of hospital stay | 9.9 (6.6, 25.3) | 10.9 (6.6, 28.9) | < 0.001 |
In-hospital death | 488 (9.8) | 1055 (29.9) | < 0.001 |