Parameters | Total sepsis patients (n = 118) |
---|---|
Demographics | |
 Age (year), mean ± SD | 54.43 ± 10.07 |
 Gender, n (%) | |
  Female | 52 (44.07) |
  Male | 66 (55.93) |
 BMI (kg/m2), mean ± SD | 25.36 ± 2.73 |
 Smoke, n (%) | 43 (36.44) |
Complications | |
 COPD, n (%) | 24 (20.34) |
 Cardiomyopathy, n (%) | 57 (48.31) |
 Chronic kidney failure, n (%) | 19 (16.10) |
 Cirrhosis, n (%) | 27 (22.88) |
Primary infection site | |
 Abdominal infection, n (%) | 41 (34.75) |
 Respiratory infection, n (%) | 27 (22.88) |
 Skin and soft tissue infection, n (%) | 23 (19.49) |
 Bloodstream infection, n (%) | 12 (10.17) |
 CNS infection, n (%) | 6 (5.08) |
 Other infection, n (%) | 9 (7.63) |
Primary organism | |
 G−, n (%) | 65 (55.08) |
 G+, n (%) | 26 (22.03) |
 Anaerobes, n (%) | 13 (11.02) |
 Fungus, n (%) | 7 (5.93) |
 Mycoplasmas, n (%) | 5 (4.24) |
 Total culture negative, n (%) | 23 (19.49) |
Biochemical indexes | |
 Scr (mg/dL), median (IQR) | 1.9 (1.4, 2.7) |
 Albumin, (g/L), median (IQR) | 27.2 (23.8, 30.7) |
 WBC (×109/L), median (IQR) | 17.5 (12.6, 27.3) |
 CRP (mg/L), median (IQR) | 91.93 (60.88, 143.81) |
 PCT (ng/mL), median (IQR) | 15.4 (8.9, 21.8) |
 Inflammatory cytokines | |
  IL-1β (pg/mL) | 13.8 (8.8, 20.2) |
  IL-6 (pg/mL) | 70.9 (45.2, 111.9) |
  TNF-α (pg/mL) | 188.1 (146.6, 233.8) |
Disease severity | |
 APACHE II score, median (IQR) | 13.0 (9.0, 18.0) |
 SOFA score, median (IQR) | 6.0 (5.0, 9.0) |