Table 2 Variations in the Breathing Pattern during Decrease of Extracorporeal Membrane Oxygenation Support in COVID-19 Patients Undergoing Pressure Support
Characteristic | Baseline | High-CO2 | P value |
|---|---|---|---|
ECMO GF (l/min) | 5.8(5.0–6.0) | 2.9(2.5-3.0) | 0.0020 |
PMI(cmH2O) | 3.0 ± 1.4 | 6.5 ± 2.1 | < 0.0001 |
ΔPOCC(cmH2O) | 5.6(4.7-8.0) | 11.1(8.5–13.1) | 0.0020 |
RR(bpm) | 13 ± 2 | 15 ± 2 | 0.0266 |
MVe (l/min) | 3.6 ± 1.3 | 5.3 ± 1.5 | < 0.0001 |
Vt (ml/kg) | 4.1 ± 1.2 | 5.3 ± 1.5 | 0.0003 |
pH | 7.42 ± 0.06 | 7.41 ± 0.05 | 0.1297 |
PaCO2 (mmHg) | 36(36–37) | 42(41–43) | 0.0020 |
PaO2 (mmHg) | 94(87–109) | 93(85–106) | 0.5742 |
Arterial Lactate(mmol/L) | 1.6 ± 0.4 | 1.8 ± 0.5 | 0.1488 |
HR(bpm) | 82 ± 14 | 89 ± 14 | 0.0078 |
MAP(mmHg) | 88 ± 11 | 92 ± 10 | 0.1776 |
NE(ug/kg/min) | 0.09 ± 0.10 | 0.09 ± 0.10 | > 0.99 |
Fentanyl (ug/h) | 60(56–75) | 60(56–75) | > 0.99 |
Propofol (mg/h) | 60(30–55) | 60(30–55) | > 0.99 |
Midazolam(mg/h) | 3 ± 2 | 3 ± 2 | > 0.99 |