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Table 3 ICU characteristics before and after propensity score matching

From: Impact of intrathecal morphine analgesia on the incidence of pulmonary complications after cardiac surgery: a single center propensity-matched cohort study

 

Entire sample

Propensity Matched Cohort

Outcomes

IVA

ITMA

IVA

ITMA

OR

(95% CI)

P-Value

 

N = 355

N = 648

N = 346

N = 346

Respiratory treatment

 Mechanical ventilation, min a

505

(275–1001)

458

(206–958)

501

(275–994)

496

(212–997)

 

0.790 b

 CPAP

267

(75.2)

483

(74.5)

260

(75.1)

259

(74.9)

0.99 (0.70–1.38)

0.931

  min per patient treated a

125

(75–215)

120

(60–240)

120

(72.5–213)

120

(75–240)

 

0.385 b

 NIV

81

(22.8)

153

(23.6)

79

(22.8)

75

(21.7)

0.94 (0.66–1.33)

0.722

  min per patient treated a

120

(60–240)

110

(60–220)

120

(60–240)

155

(60–275)

 

0.470 b

Opioid administration

Day 1

 Morphine

265

(74.7)

400

(61.7)

258

(74.6)

211

(61.0)

0.55 (0.40–0.76)

<0.001

  mg per patient a

15

(8–24)

8.5

(4–15.5)

15

(8–24)

8.0

(4–16)

 

<0.001 b

 Fentanyl

119

(33.5)

165

(26.1)

115

(33.2)

92

(26.6)

0.69 (0.51–1.00)

0.052

  mcg per patient a

276

(125–583)

160

(75–400)

276

(125–601)

150

(73–390)

 

0.002 b

Day 2

 Morphine

127

(39.7)

196

(35.1)

123

(39.6)

111

(35.9)

0.86 (0.62–1.17)

0.334

  mg per patient a

8.0

(3–13)

8.0

(3–14)

7.0

(3–14)

8.0

(3–13)

 

0.275 b

 Fentanyl

50

(15.6)

86

(15.4)

48

(15.4)

50

(16.2)

1.05 (0.69–1.59)

0.831

  mcg per patient a

348

(100–1136)

175

(50–641)

348

(100–1170)

188

(100–545)

 

0.500 b

Postoperative pain

Day1

  Pain score a

2.9

(1.3–4.0)

1.9

(0.0–3.3)

3.0

(1.3–4.0)

1.8

(0.0–3.2)

 

<0.001 b

  Pain score ≥ 5

51

(15.0)

50

(8.1)

50

(15.1)

24

(7.2)

0.45 (0.26–0.78)

0.004

Day2

  Pain score a

2.4

(1.0–4.0)

2.0

(0.4–3.7)

2.5

(1.0–4.0)

2.0

(0.1–3.8)

 

0.853 b

  Pain score ≥ 5

40

(17.1)

42

(10.7)

39

(17.3)

2753

(12.1)

0.75 (0.38–1.46)

0.400

  1. Data given as number (percentage) unless otherwise indicated. Conditional logistic regression was used for statistical tests in the matched cohort unless otherwise indicated
  2. IVA intravenous analgesia; ITMA intrathecal morphine analgesia; CPAP continuous positive airway pressure; NIV non-invasive ventilation
  3. a Data given as median (interquartile range)
  4. b Wilcoxon signed-rank test