Table 2 Intraoperative data on control and intervention groups
Original Cohort | Matched Cohort | |||||
|---|---|---|---|---|---|---|
Control (n = 147) | Intervention (n = 109) | P | Control (n = 84) | Intervention (n = 84) | P | |
Type of surgery | 0.04 | 0.48 | ||||
Gastrointestinal, n (%) | 47 (32%) | 59 (53.2%) | 29 (34.3%) | 47 (56%) | ||
Gynecological, n (%) | 7 (4.8%) | 3 (2.3%) | 1 (1.2%) | 3 (3.6%) | ||
Vascular, n (%) | 65 (44.2%) | 26 (23.9%) | 39 (46.4%) | 21 (25%) | ||
Urological, n (%) | 15 (10.2%) | 21 (19.3%) | 10 (11.9%) | 13 (15.5%) | ||
Combined interventions, n (%) | 13 (8.8%) | 1 (0.9%) | 5 (6%) | - | ||
Respiratory settings | ||||||
PEEP (mmHg), mean ± SD | 5.3 ± 1.5 | 5.5 ± 1 .1 | 0.47 | 5.2 ± 1.8 | 5.4 ± 1.1 | 0.31 |
Tidal volume (mL/kg), mean ± SD | 7.6 ± 1.4 | 8.1 ± 1.2 | 0.003 | 7.7 ± 1.2 | 8.2 ± 1.2 | 0.05 |
RR (breaths/min), mean ± SD | 11.5 ± 1.2 | 11.5 ± 1.2 | 0.94 | 11.5 ± 1.3 | 11.5 ± 1.2 | 0.92 |
FiO2 (%), mean ± SD | 49 ± 8 | 49 ± 7 | 0.52 | 50 ± 7 | 48 ± 6 | 0.04 |
Physiologic status at start of surgery | ||||||
HR (BPM), mean ± SD | 76 ± 13 | 71 ± 15 | 0.28 | 71 ± 12 | 71 ± 15 | 0.86 |
MAP (mmHg), mean ± SD | 97 ± 15 | 88 ± 17 | 0.03 | 100 ± 11 | 91 ± 17 | 0.06 |
SpO2 (%), mean ± SD | 95 ± 7 | 97 ± 2 | 0.10 | 95 ± 10 | 97 ± 2 | 0.11 |
Hematocrit (%), mean ± SD | 29 ± 6 | 34 ± 7 | 0.03 | 30 ± 5 | 32 ± 7 | 0.24 |
Physiologic status at end of surgery | ||||||
HR (BPM), mean ± SD | 74 ± 14 | 73 ± 14 | 0.52 | 74 ± 13 | 72 ± 13 | 0.45 |
MAP (mmHg), mean ± SD | 83 ± 13 | 79 ± 16 | 0.11 | 82 ± 14 | 80 ± 16 | 0.65 |
CVP (mmHg), mean ± SD | 12 ± 4 | 11 ± 7 | 0.68 | 12 ± 3 | 11 ± 8 | 0.93 |
SpO2 (%), mean ± SD | 98 ± 1 | 98 ± 1 | 0.42 | 98 ± 1 | 98 ± 1 | 0.95 |
Hematocrit (%), mean ± SD | 34 ± 6 | 33 ± 6 | 0.65 | 34 ± 6 | 33 ± 5 | 0.40 |
Fluid administered intraoperatively | ||||||
Crystalloids (mL), median (IQ 25–75) | 4500 (3000–7000) | 5200 (3500–6850) | 0.24 | 5000 (3750–8862) | 4500 (3200-6500) | 0.01 |
Colloids (mL), median (IQ 25–75) | 1000 (500-1000) | 900 (500-1000) | 0.46 | 1000 (500-1000) | 900 (500-1000) | 0.33 |
Number of patients transfused, n (%) | 64 (43.5%) | 51 (46.8%) | 0.6 | 44 (52.4%) | 39 (46.4%) | 0.44 |
RBCP units/patient, median (IQ 25–75) | 1.7 (0.9–2.5) | 1.7 (0.9–2.0) | 0.08 | 2.0 (1.7–2.6) | 1.7 (0.9–2.0) | 0.01 |
Intraoperative noradrenaline, n (%) | 10 (6.8%) | 18 (16.5%) | 0.01 | 5 (3%) | 9 (5.4%) | 0.4 |
Intraoperative dobutamine, n (%) | 2 (1.4%) | 7 (6.4%) | 0.04 | 1 (0.6%) | 5 (3%) | 0.21 |
Surgery length (min), mean ± SD | 324 ± 147 | 410 ± 165 | 0.001 | 349 ± 141 | 355 ± 130 | 0.39 |