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Table 1 Baseline characteristics

From: A pragmatic multi-center trial of goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery

 

Original Cohort

Matched Cohort

Control (n = 147)

Intervention (n = 109)

P

Control (n = 84)

Intervention (n = 84)

P

Male, n (%)

91 (61.9%)

73 (67%)

0.40

53 (63.1%)

54 (64.3%)

0.87

Age (y), mean ± SD

71.1 ± 7.4

69.5 ± 7.0

0.07

69.5 ± 7.2

70.5 ± 7.0

0.39

Weight (kg), mean ± SD

66.1 ± 14.2

66.3 ± 13.6

0.87

65.9 ± 13.5

65.7 ± 13.9

0.92

ASA Score

  

0.16

  

0.76

 P 2 score, n (%)

74 (51.3%)

63 (57.8%)

 

45 (53.6%)

46 (54.8%)

 

 P 3 score, n (%)

69 (46.9%)

46 (42.2%)

 

38 (45.2%)

38 (45.2%)

 

 P 4 score, n (%)

4 (2.7%)

-

 

1 (1.2%)

-

 

Chronic diseases

 Non-dialytic renal failure, n (%)

32 (21.9%)

14 (12.8%)

0.03

16 (19%)

9 (10.7%)

0.13

 Cirrhosis, n (%)

1 (0.7%)

5 (4.6%)

0.04

1 (1.2%)

3 (3.6%)

0.31

 Chronic obstructive pulmonary disease, n (%)

21 (14.3%)

17 (15.6%)

0.77

13 (15.5%)

11 (13.1%)

0.66

 Hypertension, n (%)

112 (76.2%)

88 (71.6%)

0.40

64 (76.2%)

65 (77.4%)

0.85

 Coronary artery disease, n (%)

46 (31.3%)

27 (24.8%)

0.25

22 (26.2%)

24 (28.6%)

0.73

 Other cardiac disease, n (%)

9 (6.1%)

5 (4.6%)

0.59

4 (4.7%)

5 (5.9%)

0.73

 Diabetes mellitus, n (%)

38 (25.8%)

28 (25.7%)

0.89

26 (30.9%)

22 (26.2%)

0.61

Preoperative biological tests

 Blood urea nitrogen (mg/dL), mean ± SD

48.3 ± 24.7

43.2 ± 22.9

0.11

47.1 ± 22.3

42.6 ± 18.0

0.17

 Creatinine (mg/dL), mean ± SD

1.3 ± 1.2

1.1 ± 0.7

0.25

1.2 ± 0.5

1.1 ± 0.7

0.62

 Plasmatic sodium (mEq/L), mean ± SD

139 ± 4

138 ± 14

0.26

139 ± 4

139 ± 4

0.60

 Plasmatic potassium (mEq/L), mean ± SD

4.4 ± 0.6

4.2 ± 0.4

0.07

4.3 ± 0.6

4.2 ± 0.5

0.76

 Glucose (mg/dL), mean ± SD

110 ± 37

114 ± 39

0.58

120 ± 53

106 ± 31

0.17

 Hemoglobin (mg/dL), mean ± SD

12.4 ± 1.9

12.4 ± 1.9

0.99

12.3 ± 1.9

12.2 ± 1.9

0.69

 Hematocrit (%), mean ± SD

38.2 ± 5.5

37.6 ± 5.2

0.41

38.0 ± 5.8

37.2 ± 5.2

0.38

 Platelets (count/μL), mean ± SD

248 ± 112

251 ± 04

0.85

250 ± 112

249 ± 104

0.93

 Leukocytes (count/mL), mean ± SD

8002 ± 3355

6814 ± 2375

0.01

7805 ± 2910

6646 ± 2322

0.06

 INR, mean ± SD

1.0 ± 0.2

1.0 ± 0.2

0.95

1.0 ± 0.2

1.1 ± 0.2

0.23

  1. Legends: ASA American Association of Anesthesiologists, INR international normalized ratio