| t0 | t1 | t2 | p (time)a | p (interaction)b |
---|---|---|---|---|---|
TVD small (mm/mm2) | Â | Â | Â | Â | - |
  Hyperoxia | 18.5 [16.5–21.6]** | 16.4 [14.6–21.6]** | 19.3 [18.2–21.3]‡* | 0.035 |  |
  Controls | 21.7 [20.0–23.8] | 22.2 [18.8–24.3] | 21.0 [19.8–23.7] | 0.705 | |
TVD medium (mm/mm2) | Â | Â | Â | Â | - |
  Hyperoxia | 0.9 [0.4–1.6] | 0.5 [0.4–0.9]** | 0.7 [0.3–1.3] | 0.268 |  |
  Controls | 1.2 [0.8–1.8] | 1.0 [0.7–1.8] | 1.1 [0.6–1.7] | 0.861 | |
PVD small (mm/mm2) | Â | Â | Â | Â | - |
  Hyperoxia | 17.4 [16.3–20.8]** | 15.4 [13.2–20.3]** | 18.4 [17.1–19.9]* | 0.058 |  |
  Controls | 20.1 [18.9–22.6] | 21.0 [18.0–23.3] | 20.0 [18.5–22.9] | 0.549 | |
PVD medium (mm/mm2) | Â | Â | Â | Â | 0.178 |
  Hyperoxia | 0.9 ± 0.6 | 0.6 ± 0.5* | 0.8 ± 0.6 | 0.142 |  |
  Controls | 1.2 ± 0.6 | 1.2 ± 0.6 | 1.1 ± 0.7 | 0.851 | |
De Backer score (n/mm) | Â | Â | Â | Â | - |
  Hyperoxia | 11.2 [9.9–13.2]** | 9.7 [8.8–13.2]** | 11.8 [10.0–13.4]‡** | 0.019 |  |
  Controls | 14.5 [12.0–15.8] | 14.1 [11.6–15.8] | 14.1 [12.7–16] | 0.951 | |
MFI small (AU) | Â | Â | Â | Â | - |
  Hyperoxia | 2.74 [2.50–2.90] | 2.67 [2.50–2.90] | 2.75 [2.52–2.92] | 0.713 |  |
  Controls | 2.67 [2.44–2.90] | 2.75 [2.60–3.00] | 2.79 [2.67–2.98] | 0.099 | |
PPV small (%) | Â | Â | Â | Â | 0.223 |
  Hyperoxia | 96 ± 3 | 94 ± 4 | 95 ± 3 | 0.149 |  |
  Controls | 94 ± 4 | 95 ± 3 | 95 ± 4 | 0.396 | |
FHI small (AU) | Â | Â | Â | Â | - |
  Hyperoxia | 0.14 [0.08–0.21] | 0.18 [0.09–0.30]* | 0.10 [0.02–0.20] | 0.551 |  |
  Controls | 0.09 [0.02–0.19] | 0.09 [0.00–0.18] | 0.09 [0.00–0.18] | 0.290 | |
BFV (μm/s) |  |  |  |  | 0.631 |
  Hyperoxia | 497 ± 63 | 489 ± 81 | 502 ± 45 | 0.741 |  |
  Controls | 520 ± 56 | 519 ± 54 | 531 ± 65 | 0.537 | |
StO2 (%) | Â | Â | Â | Â | 0.655 |
  Hyperoxia | 80 ± 8 | 82 ± 8 | 82 ± 7 | 0.261 |  |
  Controls | 81 ± 9 | 81 ± 8 | 82 ± 9 | 0.824 | |
StO2 downslope (%/min) | Â | Â | Â | Â | - |
  Hyperoxia | −7.9 [−9.1, −7.0] | −7.7 [−9.3, −6.8] | −9.4 [−11.0, −7.9]‡ | 0.003 |  |
  Controls | −8.1 [−9.7, −6.8] | −7.9 [−10.1, −7.0] | −8.6 [−9.9, −6.9] | 0.212 | |
StO2 upslope (%/min) | Â | Â | Â | Â | - |
  Hyperoxia | 133 [98–243] | 194 [145–274] | 192 [140–244] | 0.101 |  |
  Controls | 194 [150–228] | 193 [139–262] | 219 [132–263] | 0.247 | |
StO2 area under the curve (%*min) | Â | Â | Â | Â | 0.284 |
  Hyperoxia | 14.6 ± 8.8 | 18.0 ± 11.8 | 13.2 ± 7.6 | 0.066 |  |
  Controls | 20.3 ± 15.1 | 19.8 ± 14.7 | 18.3 ± 13.3 | 0.660 | |
THI (AU) | Â | Â | Â | Â | 0.884 |
  Hyperoxia | 11.0 ± 3.2 | 11.4 ± 3.8 | 11.8 ± 3.2 | 0.374 |  |
  Controls | 12.6 ± 2.2 | 12.7 ± 3.5 | 13.0 ± 3.1 | 0.801 |