Plasma pro-atrial natriuretic peptide to estimate fluid balance during open and robot-assisted esophagectomy: a prospective observational study

Table 2 Perioperative fluid administration during open (OE) and robot-assisted esophagectomy (RE)

	OE (n = 25)	RE (n = 25)	P-value
Fluid administration, ml^a	2600 (2400–3166)	2500 (2150–2825)	0.2
Electrolytes, ml^b	1993 (1725–2475)	2000 (1700–2300)	0.7
Human albumin, Voluven & PRBC, ml	500 (500–938)	500 (250–750)	0.2
Ephedrine, mg	2.5 (0–14)	5.0 (0–13)	0.9
Phenylephrine, mg	0.1 (0–0.3)	0.2 (0–0.4)	0.9
Vasopressor infusion, ml/min	0.14 (0.1–0.2)	0.12 (0.1–0.2)	0.6
Fluid loss, ml^c	1018 (839–1345)	655 (445–1065)	0.01
Blood loss, ml	600 (390–855)	250 (150–375)	0.01
Diuresis, ml	410 (296–599)	345 (300–490)	0.5
Fluid balance, ml^d	1528 (1316–1834)	1705 (1390–1983)	0.4

Values are medians with interquartile range. P-values by Mann–Whitney U-test. ^aFluid administered during anesthesia including medicine and packed red blood cells (PRBC), ^bprimarily lactated Ringer’s solution, ^cFluid loss = diuresis and blood loss, ^dFluid balance = fluid infusion – fluid loss. For vasopressor infusion norepinephrine or phenylephrine were used

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