Association between the -159C/T polymorphism in the promoter region of the CD14 gene and sepsis: a meta-analysis

BMC Anesthesiology

Table 1 Characteristics of studies included in the meta-analysis

Study	Ethnicity	SNP genotyping assay	Patient group	No. of Cases	HWE^a	Sepsis definition	Susceptibility reported	Outcome reported
Barber, 2007 [28]	Caucasian	PCR	Burn ICU	233	Yes	No	No	Yes
Bronkhorst, 2013 [33]	Caucasian	High-resolution Melting Analysis	Trauma center	219	Yes	Yes	Yes	No
D’Avila, 2006 [30]	Caucasian	PCR-RFLP	General ICU	85	Yes	Yes	Yes	Yes
Dong, 2009 [34]	Asian	PCR-RFLP	Burn ICU	77	Yes	Yes	Yes	No
Dong, 2010 [35]	Asian	PCR-RFLP	Burn ICU	35	Yes	Yes	Yes	Yes
Fallavena, 2009 [16]	Caucasian	Sequence Analysis	ICU	514	Yes	Yes	Yes	Yes
Gibot, 2002 [22]	Caucasian	PCR-RFLP	ICU	212	Yes	Yes	Yes	Yes
Gu, 2008 [29]	Asian	PCR-RFLP	Trauma center	105	Yes	Yes	Yes	No
Heesen, 2002 [25]	Caucasian	Fluorescence-labeled Hybridization Probes	Trauma center	58	Yes	Yes	Yes	No
Hubacek, 2000 [26]	Caucasian	PCR	ICU	204	Yes	No	No	Yes
Jessen, 2007 [39]	Caucasian	PCR-RFLP	ICU	452	Yes	Yes	No	Yes
Lin, 2004 [32]	Asian	PCR-RFLP	Burn ICU	16	Yes	Yes	Yes	Yes
Nakada, 2005 [40]	Asian	PCR-RFLP	Surgical ICU	197	Yes	Yes	Yes	No
Shimada, 2011 [41]	Asian	Fluorescence-labeled Hybridization probes	ICU	224	Yes	Yes	No	Yes

^aHardy-Weinberg equilibrium (HWE) was evaluated using the goodness-of-fit chi-square test. P values were presented. P > 0.05 was considered representative of a departure from HWE

ISSN: 1471-2253