From: Observational study on patterns of neuromuscular blockade reversal
Total dose of NMB (ED 95 equivalent)a | Last dose of NMB (ED 95 equivalent)a | Time between last NMB & first neostigmine dose (minutes)b | Time between first neostigmine dose & extubation (minutes)b | |
---|---|---|---|---|
Median [IQR] | Median [IQR] | Median [IQR] | Median [IQR] | |
Last TOF prior to reversal | ||||
0/4 | 3.5 [2.4, 5.2] | 1.3 [0.7, 2.4] | 52.0 [36.0, 80.3] | 12.0 [8.0, 18.0] |
1/4 | 4.0 [2.8, 5.8] | 0.8 [0.5, 1.7] | 42.0 [29.0, 59.0] | 12.5 [8.0, 19.0] |
2/4 | 4.0 [2.8, 5.9] | 0.7 [0.4, 1.4] | 43.6 [31.0, 61.0] | 12.8 [8.0, 18.9] |
3/4 | 4.0 [2.7, 5.8] | 0.7 [0.4, 1.5] | 49.0 [35.0, 68.0] | 12.4 [8.0, 19.0] |
4/4 | 3.5 [2.5, 5.3] | 0.8 [0.5, 1.8] | 65.0 [44.0, 95.0] | 12.7 [8.0, 19.0] |
Undocumented | 3.3 [2.2, 5.1] | 0.7 [0.4, 1.8] | 43.0 [24.0, 76.0] | 12.0 [7.3, 18.0] |
WHO BMI categoryc | ||||
Underweight | 2.9 [2.0, 4.4] | 0.8 [0.5, 1.6] | 57.4 [39.0, 86.4] | 13.8 [9.0, 21.0] |
Normal Weight | 3.3 [2.2, 4.9] | 0.8 [0.4, 1.8] | 58.0 [39.0, 86.0] | 13.0 [8.0, 19.0] |
Overweight | 3.6 [2.5, 6.3] | 0.7 [0.4, 1.8] | 58.9 [39.0, 87.9] | 12.1 [8.0, 19.0] |
Class I Obese | 3.8 [2.7, 5.7] | 0.8 [0.5, 1.9] | 59.0 [39.0, 87.5] | 12.1 [8.0, 19.0] |
Class II Obese | 4.0 [2.7, 5.9] | 0.8 [0.5, 2.0] | 58.5 [39.1, 88.1] | 12.3 [8.0, 19.0] |
Class III Obese | 4.2 [2.9, 6.3] | 0.8 [0.5, 1.9] | 57.0 [38.0, 85.0] | 12.9 [8.0, 19.0] |