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Table 2 Biochemical markers before surgery

From: Effect of the severity of liver dysfunction on the minimum alveolar concentration of sevoflurane responding to an electronic stimulation in cirrhotic patients

 

Group N

Group A

Group B

P-value

TBIL (μmol/l)

9.8 (5.7,24.2)

16.85 (12.6,26.6)

42.9 (18.7,620.3)a,b

<0.001

DBIL (μmol/l)

3.05 (2.1,7.9)

7.25 (5.2,9.9)

15.85 (7.9,453.9)a, b

<0.001

IBIL (μmol/l)

6.65 (3.5,16.3)

10.50 (6.8,16.7)

20.1 (6.4,166.4)a

0.003

ALT (IU/l)

21.5 (16,56)

50.0 (22,156)

25.5 (10,80)a

0.016

AST (IU/l)

24.5 (19,37)

41.5 (23,142)

37.5 (10,119)a

0.014

ALB (g/l)

41.83 ± 3.83

39.13 ± 2.8

29.63 ± 4.12a, b

<0.001

LDH (IU/l)

144.5 (105,247)

162.5 (56,312)

148 (105,197)

0.451

BUN (μmol/l)

6.07 (4.04,67)

5. 1 (3.59,6.72)

4.0 (3.22,11.38)

0.192

SCr (μmol/l)

91.8 (57.8,101.9)

79 (66.2,96.1)

75.05 (57,138)

0.81

Ammonia (μmol/l)

35.5 ± 20.42

49.6 ± 26.81

57.0 ± 25.99

0.158

PT (s)

10.7 (10.4,12)

12.65 (11.3,14.5)

17.4 (13.7,23.4)a, b

<0.001

APTT (s)

27.45 (22.1,32.5)

30.05 (25.9,36.1)

41.45 (2.07,59)a

0.001

FIB (g/l)

2.83 (1.71,4.25)

2.78 (1.78,6.16)

1.22 (0.63,3.64)a

0.015

  1. Data with normal distribution were presented as the means and SDs. Data without normal distribution were presented as medians with maximum and minimum. The P-values were derived from ANOVA or Wilcoxon’s signed rank test. Bonferroni or Dunnett T3 tests were used for post hoc paired comparisons
  2. Abbreviations: TBIL total bilirubin, DBIL direct bilirbubin, IBIL indirect blilirubin, ALT alanine aminotransferase, AST aspartame aminotransferase, ALB albumin, LDH lactate dehydrogenase, BUN urea nitrogen, SCr serum creatinine, PT prothrombin time, APTT activated partial thromboplastin time, FIB fibrinogen
  3. aGroup B vs. Group N, P < 0.05
  4. bGroup B vs. Group A, P < 0.05