From: The effects of topical and intravenous JM-1232(-) on cerebral pial microvessels of rabbits
JM-1232(-) concentration (mol /L) (n=8) | ||||||||
---|---|---|---|---|---|---|---|---|
10-11pre | 10-11post | 10-9pre | 10-9post | 10-7pre | 10-7post | 10-5pre | 10-5post | |
MAP (mmHg) | 100 ± 5 | 100 ± 9 | 101 ± 10 | 102 ± 11 | 103 ± 11 | 101 ± 11 | 102 ± 11 | 102 ± 11 |
HR (bpm) | 247 ± 12 | 251 ± 16 | 245 ± 17 | 246 ± 16 | 247 ± 18 | 245 ± 19 | 241 ± 19 | 245 ± 28 |
RT(°C) | 39.5 ± 0.4 | 39.4 ± 0.4 | 39.4 ± 0.4 | 39.5 ± 0.5 | 39.5 ± 0.4 | 39.4 ± 0.5 | 39.4 ± 0.5 | 39.4 ± 0.5 |
pH | 7.40 ± 0.05 | 7.40 ± 0.04 | 7.41 ± 0.03 | 7.40 ± 0.05 | 7.42 ± 0.02 | 7.42 ± 0.03 | 7.41 ± 0.03 | 7.41 ± 0.03 |
PaCO2 (mmHg) | 43 ± 2 | 43 ± 3 | 43 ± 2 | 42 ± 2 | 41 ± 2 | 42 ± 2 | 42 ± 2 | 42 ± 3 |
PaO2 (mmHg) | 472 ± 62 | 484 ± 43 | 489 ± 41 | 482 ± 54 | 482 ± 44 | 478 ± 66 | 498 ± 39 | 501 ± 35 |
Na+ (mEq/L) | 142 ± 1 | 142 ± 1 | 142 ± 1 | 141 ± 1 | 142 ± 1 | 141 ± 1 | 141 ± 2 | 142 ± 2 |
K+ (mEq/L) | 3.0 ± 0.4 | 3.0 ± 0.2 | 3.0 ± 0.2 | 3.0 ± 0.2 | 3.0 ± 0.2 | 3.0 ± 0.3 | 3.1 ± 0.3 | 3.0 ± 0.3 |
BS (mg/dl) | 134 ± 18 | 133 ± 16 | 133 ± 10 | 132 ± 9 | 132 ± 10 | 130 ± 15 | 129 ± 9 | 128 ± 13 |
BE | 2.4 ± 1.7 | 1.7 ± 2.3 | 1.4 ± 2.7 | 1.5 ± 2.6 | 1.8 ± 2.3 | 2.0 ± 2.1 | 1.6 ± 2.1 | 1.6 ± 2.1 |
Lactate (mmol/L) | 1.5 ± 0.6 | 1.4 ± 0.5 | 1.5 ± 0.6 | 1.6 ± 0.7 | 1.6 ± 0.7 | 1.6 ± 0.7 | 1.7 ± 0.7 | 1.8 ± 0.6 |