From: Human physiologically based pharmacokinetic model for propofol
PBPK Model Bolus + Infusion | Age Group | Individual Fits | Average Fits |
---|---|---|---|
 | 18–34 years | 13.5% | 18.5% |
 | 35–65 years | 16.1% | 23.8% |
 | >65 | 15.4% | 17.6% |
 | Average | 15.0% | 20.0% |
NONMEM Model Infusion Only [20] | 14.18% | 23% No Covariates 17.39% 5 Covariates |