Table 3 Time to remedication
From: Individual patient meta-analysis of single-dose rofecoxib in postoperative pain
Pain model | Drug & dose (mg) | Number of trials | Number of patients | TRR50(hrs) |
|---|---|---|---|---|
Dental | Rofecoxib 50 mg | 13 | 1330 | 15.5 |
| Â | Ibuprofen 400 mg | 6 | 303 | 7.1 |
| Â | Diclofenac 50 mg | 1 | 121 | 1.6 |
| Â | Ibuprofen 400 mg | 6 | 303 | 7.1 |
| Â | Naproxen 550 mg | 2 | 88 | 9.3 |
| Â | Oxycodone 5 mg + paracetamol 325 mg | 2 | 180 | 3.1 |
| Â | Paracetamol 600 mg + codeine 60 mg | 2 | 360 | 3.8 |
| Â | Placebo | 13 | 570 | 1.6 |
Postsurgical | Rofecoxib 50 mg | 1 | 110 | 5.8 |
| Â | Naproxen 550 mg | 1 | 55 | 5.9 |
| Â | Placebo | 1 | 53 | 2.8 |