From: Covariates of intravenous paracetamol pharmacokinetics in adults
Sequential nested model | PPVt2 | BSVR2 | BOV2 | PPVP2 | PPVP2/PPVt2 |
---|---|---|---|---|---|
No covariates | 0.19 | 0.19 | 0 | 0 | 0 |
Allometric scaling (TBW) | 0.19* | 0.10 | 0.0413 | 0.0487 | 0.256 |
Allometric scaling (NFM) | 0.19* | 0.0889 | 0.0557 | 0.0454 | 0.239 |
F AGECL | 0.19* | 0.0799 | 0.0557 | 0.0544 | 0.286 |
F PREGCL | 0.19* | 0.0803 | 0.0513 | 0.0584 | 0.3074 |
F ABDCL | 0.19* | 0.0605 | 0.0533 | 0.0762 | 0.401 |