Table 4 Overall survival (OS) by patient characteristics
Variable | Level | N | Event | Median OS time in months (95% CI) | OS rate at 3 years (95% CI) | OS rate at 5 years (95% CI) | P-value |
|---|---|---|---|---|---|---|---|
All patients | 636 | 243 | 82.39 (78.65,NA) | 0.72 (0.69,0.76) | 0.62 (0.58,0.66) | ||
Age | < 66 | 291 | 83 | NA (NA,NA) | 0.8 (0.76,0.85) | 0.71 (0.65,0.76) | < 0.0001 |
> = 66 | 345 | 160 | 74.84 (61.17,NA) | 0.66 (0.61,0.71) | 0.55 (0.5,0.61) |  | |
BMI | < =25 | 241 | 111 | 77.63 (53.78,NA) | 0.65 (0.6,0.72) | 0.53 (0.47,0.6) | 0.0014 |
>25 | 395 | 132 | NA (79.24,NA) | 0.77 (0.73,0.81) | 0.68 (0.63,0.73) | Â | |
Gender | Female | 298 | 90 | NA (NA,NA) | 0.81 (0.76,0.86) | 0.7 (0.65,0.76) | < 0.0001 |
Male | 338 | 153 | 69.32 (59.99,NA) | 0.65 (0.6,0.71) | 0.55 (0.5,0.61) | Â | |
ASA | 2 | 66 | 18 | NA (77.63,NA) | 0.8 (0.71,0.91) | 0.72 (0.61,0.85) | 0.0405 |
3 | 531 | 203 | NA (79.24,NA) | 0.72 (0.69,0.76) | 0.62 (0.58,0.66) | Â | |
4 | 38 | 22 | 58.2 (34.33,NA) | 0.61 (0.47,0.78) | 0.5 (0.36,0.69) | Â | |
Stage | 1 | 351 | 104 | NA (NA,NA) | 0.82 (0.78,0.86) | 0.71 (0.66,0.76) | < 0.0001 |
2 | 131 | 58 | 77.63 (62.06,NA) | 0.69 (0.62,0.78) | 0.58 (0.5,0.68) | Â | |
3 | 152 | 81 | 45.99 (31.64,81.7) | 0.53 (0.46,0.62) | 0.45 (0.37,0.54) | Â | |
Preoperative | N | 525 | 188 | NA (81.7,NA) | 0.75 (0.71,0.79) | 0.65 (0.61,0.69) | 0.0001 |
Hb < 12 g/dL | Y | 110 | 55 | 58.51 (37.42,NA) | 0.6 (0.51,0.7) | 0.48 (0.39,0.59) |  |
Perioperative | N | 576 | 207 | NA (79.24,NA) | 0.75 (0.71,0.79) | 0.65 (0.61,0.69) | < 0.0001 |
BT | Y | 60 | 36 | 33.71 (22.5,NA) | 0.48 (0.37,0.63) | 0.35 (0.24,0.5) | Â |
Number of units | 0 | 576 | 207 | NA (79.24,NA) | 0.75 (0.71,0.79) | 0.65 (0.61,0.69) | < 0.0001 |
Transfused | 1-3 | 36 | 23 | 30.39 (19.84,NA) | 0.47 (0.33,0.68) | 0.32 (0.19,0.53) | Â |
4-9 | 15 | 8 | 54.99 (24.24,NA) | 0.56 (0.35,0.9) | 0.4 (0.21,0.78) | Â | |
>10 | 7 | 4 | 23.26 (4.76,NA) | 0.36 (0.12,1) | 0.36 (0.12,1) | Â | |
Preoperative | N | 532 | 187 | NA (81.7,NA) | 0.75 (0.72,0.79) | 0.65 (0.61,0.7) | < 0.0001 |
Chemo-radiation | Y | 104 | 56 | 51.41 (34.03,NA) | 0.58 (0.49,0.68) | 0.46 (0.37,0.57) | Â |
Postoperative | Chemo only | 137 | 40 | NA (81.8,NA) | 0.8 (0.73,0.87) | 0.72 (0.65,0.81) | < 0.0001 |
Chemo-radiation | Chemo-radiation | 55 | 32 | 50.85 (34.03,NA) | 0.58 (0.46,0.73) | 0.43 (0.31,0.6) | Â |
None | 408 | 147 | NA (75.53,NA) | 0.74 (0.7,0.78) | 0.64 (0.59,0.69) | Â | |
Radiation only | 35 | 24 | 37.52 (23.26,65.05) | 0.5 (0.36,0.7) | 0.32 (0.2,0.53) | Â |