Table 2 Recurrence free survival (RFS) by patient characteristics
Variable | Level | N | Event | Median RFS time in months (95% CI) | RFS rate at 3 years (95% CI) | RFS rate at 5 years (95% CI) | P-value |
|---|---|---|---|---|---|---|---|
All patients | 599 | 277 | 68.79 (61.4,81.8) | 0.65 (0.61,0.69) | 0.54 (0.5,0.59) | ||
Age (years) | < 66 | 277 | 107 | 81.7 (74.24,NA) | 0.69 (0.64,0.75) | 0.61 (0.55,0.67) | 0.008 |
> = 66 | 322 | 170 | 56.67 (43.69,68.79) | 0.61 (0.56,0.67) | 0.49 (0.44,0.55) | ||
BMI | < =25 | 223 | 115 | 53.48 (37.42,NA) | 0.58 (0.51,0.65) | 0.46 (0.4,0.54) | 0.02 |
>25 | 376 | 162 | 75.33 (67.05,NA) | 0.69 (0.65,0.74) | 0.59 (0.54,0.65) | ||
Gender | F | 281 | 114 | 87.52 (72.34,NA) | 0.71 (0.65,0.76) | 0.62 (0.56,0.68) | 0.0002 |
M | 318 | 163 | 53.78 (41.85,68.66) | 0.6 (0.55,0.66) | 0.47 (0.42,0.54) | ||
ASA | 2 | 63 | 23 | NA (63.24,NA) | 0.7 (0.59,0.83) | 0.62 (0.5,0.76) | 0.04 |
3 | 500 | 230 | 69.97 (60.35,NA) | 0.65 (0.61,0.69) | 0.55 (0.5,0.59) | ||
4 | 35 | 24 | 39.13 (20.4,NA) | 0.56 (0.42,0.76) | 0.38 (0.25,0.59) | ||
Stage | 1 | 332 | 121 | 87.19 (81.8,NA) | 0.75 (0.71,0.8) | 0.64 (0.59,0.7) | < 0.0001 |
2 | 125 | 74 | 48.65 (27.73,66.52) | 0.55 (0.46,0.64) | 0.43 (0.35,0.53) | ||
3 | 140 | 82 | 31.44 (20.01,67.05) | 0.49 (0.41,0.58) | 0.4 (0.33,0.5) | ||
Preoperative | N | 497 | 222 | 74.24 (65.54,NA) | 0.67 (0.63,0.72) | 0.57 (0.52,0.61) | 0.001 |
Hb < 12 g/dL | Y | 101 | 55 | 39.13 (23.75,NA) | 0.52 (0.43,0.63) | 0.42 (0.33,0.54) | |
BT | N | 548 | 244 | 74.24 (66.52,7.52) | 0.67 (0.63,0.71) | 0.57 (0.52,0.61) | 0.0002 |
Y | 51 | 33 | 23.98 (16.98,55.22) | 0.4 (0.28,0.57) | 0.29 (0.18,0.45) | ||
Number of units | 0 | 548 | 244 | 74.24 (66.52,87.52) | 0.67 (0.63 0.71) | 0.57 (0.52,0.61) | 0.001 |
Transfused | 1-3 | 31 | 19 | 24.34 (10.32,NA) | 0.4 (0.25,0.63) | 0.32 (0.19,0.55) | |
4-9 | 12 | 8 | 24.24 (22.21,NA) | 0.42 (0.2,0.88) | 0.21 (0.06,0.72) | ||
>10 | 6 | 5 | 17.85 (3.45,NA) | 0.33 (0.11,1) | 0.17 (0.03,1) | ||
Preoperative | N | 501 | 217 | 77.63 (66.69,NA) | 0.69 (0.65,0.73) | 0.58 (0.53,0.62) | < 0.0001 |
Chemo-radiation | Y | 98 | 60 | 21.71 (13.83,55.22) | 0.45 (0.36,0.56) | 0.38 (0.29,0.49) | |
Postoperative | Chemo only | 132 | 57 | 81.8 (60.35,NA) | 0.67 (0.59,0.76) | 0.58 (0.5,0.68) | < 0.0001 |
Therapy | Chemo/Radiation | 54 | 35 | 34.92 (17.35,74.24) | 0.49 (0.36,0.65) | 0.39 (0.28,0.56) | |
None | 378 | 160 | 75.33 (66.52,NA) | 0.69 (0.65,0.74) | 0.58 (0.53,0.63) | ||
Radiation only | 35 | 25 | 20.66 (3.47,51.35) | 0.38 (0.25,0.59) | 0.27 (0.15,0.46) |