Table 2 Patient characteristic according to 1-year survival
Variable | Survivors (n = 31) | Non- survivors (n = 18) | p |
|---|---|---|---|
Demographics | |||
Median age, y | 60 (49.5-68.5) | 72 (68.3-76) | 0.031 |
Female sex | 10 (32%) | 4 (22%) | ns |
Previous medical history | |||
Diabetes mellitus | 4 (13%) | 2 (11%) | ns |
Hypertension | 9 (29%) | 3 (17%) | ns |
Cardiac disease | 8 (26%) | 4 (22%) | ns |
Pre-existing therapy | 14 (45%) | 10 (56%) | ns |
Clinical data | |||
APACHE II | 22 (16–26) | 28.5 (21–34) | 0.009 |
SOFA score | 10 (9–13) | 13 (11–14) | 0.024 |
Mechanical ventilation | 29 (94%) | 15 (83%) | ns |
Biochemical markers | |||
Creatinine, μmol/l | 154 (88–221) | 171 (105–238) | ns |
Lactate, mmol/l | 2.2 (1.6-3.2) | 2.5 (1.7-4.4) | ns |
hsTNT, ng/l | 60 (17.0-99.5) | 168 (89.8-358) | 0.003 |
BNP, pmol/l | 159 (84–339) | 241 (149–446) | 0.26 |
Echocardiographic data | |||
Survivors (n = 28) | Non- survivors (n = 18) | ||
LVEF,% | 48 (40–55) | 45 (36–65) | 0.87 |
La volume, ml/m2 | 24 (20–27) | 31 (25–36) | 0.024 |
AVPD, mm | 11.5 (8.8- 13) | 9.0 (7.5-11) | 0.087 |
E, cm/s | 83.5 (68.8-96.3) | 102.5 (75.5-113.0) | ns |
A, cm/s | 67.5 (57.0-92.3) | 63.5 (40.0-86.0) | ns |
E/A | 1.2 (0.85-1.4) | 1.4 (1.0-1.9) | ns |
DT, ms | 170 (150–200) | 160 (135–195) | ns |
TDIs, cm/s | 8.5 (7.2-9.7) | 8.7 (6.7-10) | ns |
é, cm/s | 8.4 (7.5-10.8) | 7.9 (6.3-9.6) | ns |
á, cm/s | 9.9 (7.7-12.3) | 8.8 (7.5-10) | ns |
E/é | 9.9 (8.1-10.9) | 11.7 (9.8-14.8) | 0.023 |
LVOT VTI, cm | 20 (15–23) | 17 (16–23) | 0.18 |