Characteristic | Group | Intraoperative period | Postoperative period | |||||||
---|---|---|---|---|---|---|---|---|---|---|
After induction of anesthesia | Fixation of the heart | 5 min after start flow | End of operation | 2 hours | 6 hours | 12 hours | 18 hours | 24 hours | ||
Control | 79.9 ± 13.5 | 76.9 ± 15.6 | 74.6 ± 14.3 | 80.2 ± 10.4 | 89.9 ± 15.3+ | 87.6 ± 12.7+ | 82.5 ± 14.8# | 80.1 ± 13.1 | 80.1 ± 13.1 | |
MAP, mm Hg | EI | 72.8 ± 8.37 | 67.8 ± 13.5+ | 72.6 ± 11.8 | 74.2 ± 12.6 | 86.1 ± 17.6+ | 81.2 ± 14.9+ | 72.0 ± 12.4 | 76.1 ± 12.4 | 75.6 ± 11.4 |
PCEA | 79.4 ± 13.6 | 67.5 ± 12.1+ | 74.7 ± 12.7 | 72.6 ± 11.4+ | 89.6 ± 14.9+ | 89.4 ± 17.5+ | 83.7 ± 17.3# | 79.1 ± 17.9 | 82.3 ± 17.0 | |
Control | 50.0 (42.3-59.8) | 59.5 (51.3-64.8)+ | 62.5 (50.5-70.5)#+ | 61.0 (55.3-74.5)#+ | 77.5 (71.0-85.0)+ | 87.5 (77.5-98.0)+ | 87.0 (80.3-101.0)#+ | 82.5 (75.0-96.8)+ | 83.5 (77.0-94.5)+ | |
HR, 1/min | EI | 52.0 (43.3-59.8) | 51.5 (44.3-63.8) | 54.5 (48.3-62.8) | 56.0 (48.3-66.0) | 66.5 (56.8-84.0)+ | 85.0 (75.5-88.8)+ | 79.5 (75.3-92.0)+ | 81.0 (73.0-89.8)+ | 80.0 (74.8-88.8)+ |
PCEA | 54.0 (48.5-64.0) | 55.0 (49.0-63.0) | 58.0 (54.0-65.0) | 61.0 (55.0-66.5) | 71.0 (64.0-86.5)+ | 91.0 (82.0-105.0)+ | 89.0 (83.0-94.0)#+ | 86.0 (78.5-91.5)+ | 86.0 (80.5-93.5)+ | |
Control | 2.20 ± 0.42 | 2.43 ± 0.59 | 2.96 ± 1.23+ | 2.70 ± 0.80 | 3.27 ± 0.74+ | 3.55 ± 0.83+ | 3.69 ± 0.78+ | 3.39 ± 0.38 | 3.46 ± 0.42+ | |
CI, l/min/m2 | EI | 2.20 ± 0.44 | 1.97 ± 0.51 | 2.55 ± 0.33+ | 2.57 ± 0.55+ | 3.12 ± 0.69+ | 3.43 ± 0.59+ | 3.43 ± 0.53+ | 3.34 ± 0.50 | 3.32 ± 0.44+ |
PCEA | 2.15 ± 0.46 | 1.89 ± 0.51 | 2.81 ± 0.75+ | 2.58 ± 0.80 | 3.27 ± 0.87+ | 3.79 ± 0.63+ | 3.46 ± 0.49+ | 3.08 ± 0.44 | 3.40 ± 0.46+ | |
Control | 3.47 ± 1.18 | 3.14 ± 1.04 | 3.88 ± 1.42 | 3.79 ± 1.24 | 4.71 ± 1.83+ | 5.01 ± 1.73+ | 5.56 ± 1.92+ | 4.96 ± 1.19+ | 4.98 ± 1.11+ | |
CFI, 1/min | EI | 3.42 ± 0.77 | 3.03 ± 0.65+ | 3.69 ± 0.69 | 3.65 ± 0.87 | 4.68 ± 0.92+ | 5.25 ± 0.76+ | 5.23 ± 1.22+ | 5.13 ± 1.14+ | 4.95 ± 1.29+ |
PCEA | 3.32 ± 0.68 | 3.08 ± 0.66 | 3.97 ± 1.04+ | 3.88 ± 1.16+ | 4.47 ± 1.21+ | 5.33 ± 1.56+ | 4.87 ± 1.22+ | 4.28 ± 1.07+ | 4.30 ± 1.14+ | |
Control | 2709 ± 500 | 2484 ± 773 | 2256 ± 725 | 2228 ± 568+ | 2150 ± 637 | 1967 ± 763+ | 1647 ± 648+ | 1731 ± 378+ | 1790 ± 428+ | |
SVRI, dyne'sec'cm-5'm-2 | EI | 2458 ± 707 | 2120 ± 600 | 1933 ± 287+ | 1953 ± 290 | 1993 ± 482 | 2035 ± 491+ | 1677 ± 456+ | 1846 ± 277+ | 1788 ± 329+ |
PCEA | 2912 ± 970 | 2299 ± 791 | 2059 ± 892 | 2112 ± 733+ | 2223 ± 554 | 2086 ± 405 | 2123 ± 487+ | 2205 ± 623*+ | 2078 ± 604+ | |
Control | 11.3 ± 3.6 | 14.0 ± 4.0#+ | 11.8 ± 3.7# | 12.7 ± 3.5#+ | 7.6 ± 3.7+ | 5.9 ± 3.1+ | 5.0 ± 4.0+ | 4.6 ± 4.2+ | 5.8 ± 4.6+ | |
CVP, mm Hg | EI | 12.5 ± 3.1 | 16.8 ± 3.2+ | 14.4 ± 2.5+ | 14.9 ± 2.3+ | 8.9 ± 3.3+ | 7.2 ± 4.8+ | 6.3 ± 4.2+ | 5.4 ± 5.3+ | 4.9 ± 3.3+ |
PCEA | 11.4 ± 2.67 | 15.0 ± 3.8+ | 13.0 ± 3.0+ | 13.4 ± 2.8+ | 8.3 ± 4.3+ | 4.3 ± 3.5#+ | 4.1 ± 3.3+ | 4.6 ± 4.0+ | 5.4 ± 3.8+ | |
Control | 689 ± 243 | 797 ± 227 | 765 ± 168 | 711 ± 117 | 729 ± 169 | 724 ± 165 | 695 ± 188 | 715 ± 199 | 710 ± 145 | |
GEDVI, ml/m2 | EI | 674 ± 215 | 661 ± 250 | 696 ± 153 | 704 ± 251 | 680 ± 149 | 659 ± 106 | 660 ± 125 | 661 ± 107 | 682 ± 115 |
PCEA | 653 ± 143 | 646 ± 159 | 722 ± 116 | 665 ± 146 | 683 ± 251 | 728 ± 139 | 728 ± 133 | 720 ± 125 | 799 ± 148 | |
Control | 697 ± 116 | 537 ± 169 | 567 ± 142 | 565 ± 145 | 803 ± 412 | 773 ± 307 | 770 ± 255 | 744 ± 412 | 915 ± 339 | |
dPmax, mm Hg/sec | EI | 542 ± 136 | 479 ± 150 | 552 ± 141 | 567 ± 201 | 803 ± 412+ | 849 ± 288+ | 880 ± 293+ | 1015 ± 421+ | 997 ± 353+ |
PCEA | 561 ± 203 | 457 ± 159 | 536 ± 179 | 578 ± 219 | 843 ± 263+ | 813 ± 177+ | 909 ± 284+ | 877 ± 243+ | 857 ± 195+ | |
Control | 24.6 ± 6.1 | 21.0 ± 6.6+ | 22.2 ± 7.0 | 22.0 ± 5.6+ | 22.3 ± 5.8 | 22.3 ± 4.7 | 24.0 ± 6.3 | 22.0 ± 5.4 | 21.7 ± 5.3 | |
GEF, % | EI | 26.2 ± 7.30 | 23.5 ± 5.4 | 26.1 ± 6.3 | 26.0 ± 7.0 | 26.7 ± 7.7 | 22.6 ± 5.0 | 24.2 ± 6.1 | 24.0 ± 5.7 | 22.9 ± 5.5 |
PCEA | 21.8 ± 7.2 | 21.2 ± 6.1 | 24.6 ± 6.2+ | 23.8 ± 6.5 | 23.9 ± 5.1 | 22.8 ± 5.7 | 21.6 ± 6.3 | 19.0 ± 5.1 | 19.6 ± 4.8 | |
Control | 9.0 (7.0-10.0) | 11.0 (8.0-14.0)+ | 9.0 (8.0-11.0) | 10.0 (7.0-11.0) | 8.0 (5.0-12.0) | 8.0 (6.0-11.0) | 10.0 (6.0-11.0) | 8.0 (5.0-14.0) | 9.0 (8.0-13.0) | |
EVLWI, ml/kg | EI | 9.0 (7.0-9.5) | 8.5 (6.8-10.5) | 9.0 (7.0-10.3) | 8.0 (6.8-10.0) | 7.5 (6.0-11.8) | 6.5 (6.0-10.3) | 6.0 (5.8-7.3)+ | 7.00 (6.8-8.8) | 7.5 (6.0-9.3) |
PCEA | 8.0 (6.3-9.8) | 9.5 (7.0-11.0) | 8.0 (7.3-11.8) | 8.0 (7.0-10.5) | 8.0 (7.0-12.8) | 6.5 (6.0-8.0) | 7.0 (5.3-8.8) | 7.5 (6.0-9.8) | 7.5 (7.0-10.8) |