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  1. Early aggressive therapy can reduce the mortality associated with severe sepsis but this relies on prompt recognition, which is hindered by variation among published severity criteria. Our aim was to test the ...

    Authors: Charis A Marwick, Bruce Guthrie, Jan EC Pringle, Shaun R McLeod, Josie MM Evans and Peter G Davey

    Citation: BMC Anesthesiology 2014 14:1

    Content type: Research article

    Published on:

  2. The primary objective of this study was to determine the efficiency of a pneumatic device in controlling cuff pressure (Pcuff) in patients intubated with polyurethane-cuffed tracheal tubes. Secondary objectives w...

    Authors: Emmanuelle Jaillette, Farid Zerimech, Julien De Jonckheere, Demosthenes Makris, Malika Balduyck, Alain Durocher, Alain Duhamel and Saad Nseir

    Citation: BMC Anesthesiology 2013 13:50

    Content type: Research article

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  3. There are wide variations in the physical designs and attributes between different brands of intravenous cannulae that makes product selection and purchasing difficult. In a systematic assessment to guide purc...

    Authors: Stanley Tay, Brian Spain, Kirstie Morandell, Jesse Gilson, Laurence Weinberg and David Story

    Citation: BMC Anesthesiology 2013 13:49

    Content type: Research article

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  4. Procalcitonin (PCT) is a reliable biomarker of sepsis and infection. The level of PCT associated with sepsis and infection in patients with traumatic brain injury is currently unknown. The purpose of this stud...

    Authors: Shuixiang Deng, Hechen Zhu, Kunlun Wang and Tongwa Cao

    Citation: BMC Anesthesiology 2013 13:48

    Content type: Research article

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  5. Although endotracheal suctioning induces alveolar derecruitment during mechanical ventilation, it is not clear whether repeated endotracheal suctioning exacerbates lung injuries. The present study aimed to det...

    Authors: Hideaki Sakuramoto, Nobutake Shimojo, Subrina Jesmin, Takeshi Unoki, Junko Kamiyama, Masami Oki, Ken Miya, Satoru Kawano and Taro Mizutani

    Citation: BMC Anesthesiology 2013 13:47

    Content type: Research article

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  6. Remifentanil enhances intraoperative hemodynamic stability, suggesting that it may decrease intraoperative blood loss when included as an adjuvant to general anesthesia. This retrospective study compared intra...

    Authors: Hiroaki Kawano, Sawa Manabe, Tomomi Matsumoto, Eisuke Hamaguchi, Michiko Kinoshita, Fumihiko Tada and Shuzo Oshita

    Citation: BMC Anesthesiology 2013 13:46

    Content type: Research article

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  7. The incidence of multi-drug resistant (MDR) gram-negative (GN) organisms including Pseudomonas and Acinetobacter spp has increased in the last decade, prompting re-evaluation of colistin for the management of the...

    Authors: Neha M Doshi, Charles H Cook, Kari L Mount, Stanislaw P Stawicki, Erin N Frazee, Heather A Personett, Garrett E Schramm, Heather M Arnold and Claire V Murphy

    Citation: BMC Anesthesiology 2013 13:45

    Content type: Research article

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  8. Methodologists have proposed the formation of a good research question to initiate the process of developing a research protocol that will guide the design, conduct and analysis of randomized controlled trials...

    Authors: Victoria Borg Debono, Shiyuan Zhang, Chenglin Ye, James Paul, Aman Arya, Lindsay Hurlburt, Yamini Murthy and Lehana Thabane

    Citation: BMC Anesthesiology 2013 13:44

    Content type: Research article

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  9. Etiologies of pediatric intensive care unit (PICU) mortality are diverse. This study aimed to investigate the pattern of PICU mortality in a regional trauma center, and explore factors associated with prolonge...

    Authors: Kam Lun E Hon, Terence Chuen Wai Poon, William Wong, Kin Kit Law, Hiu Wing Mok, Ka Wing Tam, Wai Kin Wong, Hiu Fung Wu, Ka Fai To, Kam Lau Cheung, Hon Ming Cheung, Ting Fan Leung, Chi Kong Li and Alexander K C Leung

    Citation: BMC Anesthesiology 2013 13:43

    Content type: Research article

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  10. Perioperative blood transfusions have been associated with poor clinical outcomes in the context of oncological surgery. Current literature is inconclusive whether blood transfusions are linked to shorter recu...

    Authors: Juan P Cata, Varun Chukka, Hao Wang, Lei Feng, Vijaya Gottumukkala, Fernando Martinez and Ara A Vaporciyan

    Citation: BMC Anesthesiology 2013 13:42

    Content type: Research article

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  11. The use of vasoconstrictor can affect the dynamic indices to predict fluid responsiveness. We investigate the effects of an increase of vascular tone on dynamic variables of fluid responsiveness in a rabbit mo...

    Authors: Juan P Bouchacourt, Juan A Riva and Juan C Grignola

    Citation: BMC Anesthesiology 2013 13:41

    Content type: Research article

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  12. In the assessment of hypovolemia the value of functional hemodynamic monitoring during spontaneous breathing is debated. The aim of our study was to investigate in spontaneously breathing subjects the changes ...

    Authors: Éva Zöllei, Viktória Bertalan, Andrea Németh, Péter Csábi, Ildikó László, József Kaszaki and László Rudas

    Citation: BMC Anesthesiology 2013 13:40

    Content type: Research article

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  14. The provision of Intensive Care (IC) can lead to a health care provider’s physical, psychological and emotional exhaustion, which may develop into burnout. We notice the absence of specific studies regarding t...

    Authors: Carla Teixeira, Orquídea Ribeiro, António Manuel Fonseca and Ana Sofia Carvalho

    Citation: BMC Anesthesiology 2013 13:38

    Content type: Research article

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  15. Mortality among critically ill patients with candidemia is very high. We sought to determine whether the choice of initial antifungal therapy is associated with survival among these patients, using need for me...

    Authors: Marcela A Ferrada, Andrew A Quartin, Daniel H Kett and Michele I Morris

    Citation: BMC Anesthesiology 2013 13:37

    Content type: Research article

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  16. AKI significantly worsens prognosis of hospitalized patients. This is particularly the case in patients with sepsis. The risk for aquiring sepsis is significantly increased in malignant diseases. Aim of the pr...

    Authors: Malte Heeg, Alexander Mertens, David Ellenberger, Gerhard A Müller and Daniel Patschan

    Citation: BMC Anesthesiology 2013 13:36

    Content type: Research article

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  17. Post-dural puncture headache (PDPH) due to excessive cerebrospinal fluid (CSF) leakage is a well-known complication of lumbar puncture. Although various factors, especially the type of spinal needle, have been...

    Authors: Keita Sakurai, Noriyuki Matsukawa, Kenji Okita, Minoru Nishio, Masashi Shimohira, Yoshiyuki Ozawa, Susumu Kobayashi, Takemori Yamawaki and Yuta Shibamoto

    Citation: BMC Anesthesiology 2013 13:35

    Content type: Research article

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  18. A multimodal and preventative approach to providing postoperative analgesia is becoming increasingly popular for children and adults, with the aim of reducing reliance on opioids. We conducted a prospective, r...

    Authors: Esra Caliskan, Mesut Sener, Aysu Kocum, Nesrin Bozdogan Ozyilkan, Semire Serin Ezer and Anis Aribogan

    Citation: BMC Anesthesiology 2013 13:34

    Content type: Research article

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  19. The α2-adrenoceptor agonist xylazine as an anesthetic has been widely used either alone or in combination with other anesthetics, such as ketamine, in veterinary clinic and research. In the last decade xylazine h...

    Authors: Yong-Fu Xiao, Bingdi Wang, Xiaoli Wang, Fenglai Du, Michael Benzinou and Yi-Xin Jim Wang

    Citation: BMC Anesthesiology 2013 13:33

    Content type: Research article

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  20. Over the last few decades intensive studies have been carried out on the molecular targets mediating general anesthesia as well as the effects of general anesthetics. The γ-aminobutyric acid type A receptor (GABA

    Authors: Changhong Dong, Anmin Hu, Yang Ni, Yunxia Zuo and Guo Hua Li

    Citation: BMC Anesthesiology 2013 13:32

    Content type: Research article

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  21. Sequential physicochemical alterations in blood and urine in the course of acute kidney injury (AKI) development have not been previously described. We aimed to describe these alterations in parallel to tradit...

    Authors: Alexandre Toledo Maciel, Marcelo Park and Etienne Macedo

    Citation: BMC Anesthesiology 2013 13:31

    Content type: Research article

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  22. The analgesic effect of a TAP block has been investigated in various surgical settings. There are however limited information about block level and block duration. Furthermore, there is a lack of information a...

    Authors: Pernille L Petersen, Karen L Hilsted, Jørgen B Dahl and Ole Mathiesen

    Citation: BMC Anesthesiology 2013 13:30

    Content type: Research article

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  23. If one party has more or better information than the other, an information asymmetry can be assumed. The aim of the study was to identify the origin of incomplete patient-related preoperative information, whic...

    Authors: Joerg Schnoor, Anja Kupfer, Babette Jurack, Ulrike Reuter, Herrmann Wrigge, Steffen Friese and Volker Thieme

    Citation: BMC Anesthesiology 2013 13:29

    Content type: Research article

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  24. Accidental intravenous exposure to bupivacaine is highly cardiotoxic and may lead to death. Positive inotropic agents are usually utilized in resuscitative efforts. We have compared the efficacy of levosimenda...

    Authors: Ulku Kandemir, Fikret Maltepe, Baran Ugurlu, Necati Gokmen and Asli Celik

    Citation: BMC Anesthesiology 2013 13:28

    Content type: Research article

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  25. Systemic vasculitis may cause life threatening complications requiring admission to an intensive care unit (ICU). The aim of this study was to evaluate outcomes of systemic vasculitis patients admitted to the ...

    Authors: Patrice Befort, Philippe Corne, Thomas Filleron, Boris Jung, Christian Bengler, Olivier Jonquet and Kada Klouche

    Citation: BMC Anesthesiology 2013 13:27

    Content type: Research article

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  26. Carbon monoxide (CO) poisoning can be a life threatening condition. Systemic hyperbaric oxygen (HBO) therapy is used to induce CO detoxification. However, little is known about the hemodynamic response to HBO ...

    Authors: Marie-Ludivine Chateau-Degat, Julien Poitras and Jacques H Abraini

    Citation: BMC Anesthesiology 2013 13:26

    Content type: Research article

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  27. The role of recombinant activated protein C (aPC) during sepsis is still controversial. It showed anti-inflammatory effect and improved the microvascular perfusion in experimental models of septic shock. The p...

    Authors: Abele Donati, Elisa Damiani, Laura Botticelli, Erica Adrario, Maria Rita Lombrano, Roberta Domizi, Benedetto Marini, Jurgen WGE Van Teeffelen, Paola Carletti, Massimo Girardis, Paolo Pelaia and Can Ince

    Citation: BMC Anesthesiology 2013 13:25

    Content type: Research article

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  28. Malignant hyperthermia (MH), a metabolic myopathy triggered by volatile anesthetics and depolarizing muscle relaxants, is a potentially lethal complication of general anesthesia in susceptible patients. The im...

    Authors: Frank Schuster, Stephan Johannsen, Daniel Schneiderbanger and Norbert Roewer

    Citation: BMC Anesthesiology 2013 13:24

    Content type: Research article

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  29. Given the acknowledged problems in sepsis diagnosis, we use a novel way with the application of the latent class analysis (LCA) to determine the operative characteristics of C-reactive protein (CRP), D-dimer (...

    Authors: Fabián A Jaimes, Gisela D De La Rosa, Marta L Valencia, Clara M Arango, Carlos I Gomez, Alex Garcia, Sigifredo Ospina, Susana C Osorno and Adriana I Henao

    Citation: BMC Anesthesiology 2013 13:23

    Content type: Research article

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  31. In trauma patients intubated in a physician-led pre-hospital trauma service we prospectively examined the rate of misplaced tracheal tubes, the presence and nature of gross airway contamination, and the value ...

    Authors: David J Lockey, Pascale Avery, Timothy Harris, Gareth E Davies and Hans Morten Lossius

    Citation: BMC Anesthesiology 2013 13:21

    Content type: Research article

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  32. In a smaller experience, the authors previously demonstrated that end-tidal carbon dioxide (PetCO2) and cardiac output (CO) had a positive association in emergently intubated trauma patients during Emergency Depa...

    Authors: C Michael Dunham, Thomas J Chirichella, Brian S Gruber, Jonathan P Ferrari, Joseph A Martin, Brenda A Luchs, Barbara M Hileman and Renee Merrell

    Citation: BMC Anesthesiology 2013 13:20

    Content type: Research article

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  33. Postoperative nausea and vomiting after general anesthesia is not only an unpleasant problem affecting 20-30% of surgical patients but may also lead to severe postoperative complications. There is a particular...

    Authors: Ignazio Tarantino, Ulrich Beutner, Walter Kolb, Sascha A Müller, Cornelia Lüthi, Andreas Lüthi, Bruno M Schmied, Thomas Clerici and Rene Warschkow

    Citation: BMC Anesthesiology 2013 13:19

    Content type: Study protocol

    Published on:

  34. Ultrasound gels may contain propylene glycol and glycerol, which are neurotoxic in high concentrations. If the needle passes through gel during regional anesthesia, gel may be injected near the nerve. It is un...

    Authors: David Belavy, Nana Sunn, Queenie Lau and Thomas Robertson

    Citation: BMC Anesthesiology 2013 13:18

    Content type: Research article

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  35. Microcirculatory driving pressure is defined as the difference between post-arteriolar and venular pressure. In previous research, an absence of correlation between mean arterial blood pressure (MAP) and micro...

    Authors: Namkje AR Vellinga, Can Ince and E Christiaan Boerma

    Citation: BMC Anesthesiology 2013 13:17

    Content type: Research article

    Published on:

  36. As peripheral nerve blockade has increased significantly over the past decade, resident education and exposure to peripheral nerve blocks has also increased. This survey assessed the levels of exposure and con...

    Authors: Tiffany Sun Moon, Eunjung Lim and Sakura Kinjo

    Citation: BMC Anesthesiology 2013 13:16

    Content type: Research article

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  37. Hyperthermic isolated limb perfusion (HILP) is used for patients with intractable or extensive in-transit metastatic melanoma of the limb to deliver high concentrations of cytotoxic agents to the affected limb...

    Authors: Heiner Ruschulte, Serena Shi, William W Tseng, Kerstin Kolodzie, Philip C Crawford, Darren B Schneider, Mohammed Kashani-Sabet, David Minor, Christian Apfel and Stanley PL Leong

    Citation: BMC Anesthesiology 2013 13:15

    Content type: Research article

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  38. Currently, in the field of general anesthesia, balanced anesthesia in combination with analgesic, hypnotic, and muscle relaxant is commonly used. Remifentanil is the standard analgesic used in balanced anesthe...

    Authors: Taketo Shinoda, Wakako Murakami, Yasuo Takamichi, Hiroki Iizuka, Masaaki Tanaka and Yuto Kuwasako

    Citation: BMC Anesthesiology 2013 13:14

    Content type: Research article

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  39. Abdominal surgery carries significant morbidity and mortality, which is in turn associated with an enormous use of healthcare resources. We describe the clinical course of 30 Intensive Care Unit (ICU) patients...

    Authors: Paola Di Carlo, Gaspare Gulotta, Alessandra Casuccio, Gianni Pantuso, Maurizio Raineri, Clizia Airò Farulla, Sebastiano Bonventre, Giuliana Guadagnino, Daniela Ingrassia, Gianfranco Cocorullo, Caterina Mammina and Antonino Giarratano

    Citation: BMC Anesthesiology 2013 13:13

    Content type: Research article

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  40. Sepsis-induced cardiac dysfunction may limit fluid responsiveness and the mechanism thereof remains unclear. Since cardiac function may affect the relative value of cardiac filling pressures, such as the recom...

    Authors: Ronald J Trof, Ibrahim Danad and AB Johan Groeneveld

    Citation: BMC Anesthesiology 2013 13:12

    Content type: Research article

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  41. Studies suggest that in patients admitted to intensive care units (ICU), physical functional status (PFS) improves over time, but does not return to the same level as before ICU admission. The goal of this stu...

    Authors: Jaqueline S Haas, Cassiano Teixeira, Claudia R Cabral, Alessandra H D Fleig, Ana Paula R Freitas, Erika C Treptow, Márcia IB Rizzotto, André S Machado, Patrícia C Balzano, Márcio P Hetzel, Daniele M Dallegrave, Roselaine P Oliveira, Augusto Savi and Silvia RR Vieira

    Citation: BMC Anesthesiology 2013 13:11

    Content type: Research article

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  42. While pentobarbital has been used extensively in neurophysiological experiments investigating activity in peripheral nerves, it has fallen out of favor as an anesthetic because of safety concerns and is often ...

    Authors: Ju-Wen Cheng, Alison I Weber and Sliman J Bensmaia

    Citation: BMC Anesthesiology 2013 13:10

    Content type: Research article

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  43. Sodium nitroprusside (SNP) is a potent vasodilator that has been used to induce deliberate hypotension in children during surgery involving significant blood loss, including craniofacial and spinal fusion proc...

    Authors: Gregory B Hammer, Sara G Connolly, Scott R Schulman, Andrew Lewandowski, Carol Cohane, Tammy L Reece, Ravinder Anand, Jeff Mitchell and David R Drover

    Citation: BMC Anesthesiology 2013 13:9

    Content type: Research article

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  44. Poor characterization of propofol pharmacokinetics and pharmacodynamics in the morbidly obese (MO) pediatric population poses dosing challenges. This study was conducted to evaluate propofol total intravenous ...

    Authors: Vidya Chidambaran, Senthilkumar Sadhasivam, Jeroen Diepstraten, Hope Esslinger, Shareen Cox, Beverly M Schnell, Paul Samuels, Thomas Inge, Alexander A Vinks and Catherijne A Knibbe

    Citation: BMC Anesthesiology 2013 13:8

    Content type: Research article

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  46. Extracorporeal membrane oxygenation (ECMO) is a supportive therapy and its success depends on optimal drug therapy along with other supportive care. Emerging evidence suggests significant interactions between ...

    Authors: Kiran Shekar, Jason A Roberts, Maree T Smith, Yoke L Fung and John F Fraser

    Citation: BMC Anesthesiology 2013 13:7

    Content type: Study protocol

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  47. Varied and fragmented care plans undertaken by different practitioners currently expose surgical patients to lapses in expected care, increase the chance for operational mistakes and accidents, and often resul...

    Authors: Thomas R Vetter, Lee A Goeddel, Arthur M Boudreaux, Thomas R Hunt, Keith A Jones and Jean-Francois Pittet

    Citation: BMC Anesthesiology 2013 13:6

    Content type: Debate

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  48. Goal-directed fluid therapy (GDFT) has been shown to reduce complications and hospital length of stay following major surgery. However, there has been no assessment regarding its use in clinical practice.

    Authors: Sanket Srinivasa, Arman Kahokehr, Mattias Soop, Matthew Taylor and Andrew G Hill

    Citation: BMC Anesthesiology 2013 13:5

    Content type: Research article

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  50. In 1993, the American Society of Anesthesiologists (ASA) published guidelines stating that automatic perioperative suspension of Do Not Resuscitate (DNR) orders conflicts with patients’ rights to self-determin...

    Authors: Christopher M Burkle, Keith M Swetz, Matthew H Armstrong and Mark T Keegan

    Citation: BMC Anesthesiology 2013 13:2

    Content type: Research article

    Published on:

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BMC Anesthesiology

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