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  1. The elderly population is highly susceptible to develop post-operative complications after major surgeries. It is not clear whether the comprehensive geriatric care models are effective in reducing adverse eve...

    Authors: Aparna Saripella, Sara Wasef, Mahesh Nagappa, Sheila Riazi, Marina Englesakis, Jean Wong and Frances Chung
    Citation: BMC Anesthesiology 2021 21:127
  2. Predicting difficult airway is challengeable in patients with limited airway evaluation. The aim of this study is to develop and validate a model that predicts difficult laryngoscopy by machine learning of nec...

    Authors: Jong Ho Kim, Haewon Kim, Ji Su Jang, Sung Mi Hwang, So Young Lim, Jae Jun Lee and Young Suk Kwon
    Citation: BMC Anesthesiology 2021 21:125
  3. Infection is a major complication following cerebral spinal fluid (CSF) diversion procedures for hydrocephalus. However, pediatric risk factors for surgical site infection (SSI) are currently not well defined....

    Authors: Miho Shibamura-Fujiogi, Jennifer Ormsby, Mark Breibart, Benjamin Warf, Gregory P. Priebe, Sulpicio G. Soriano, Thomas J. Sandora and Koichi Yuki
    Citation: BMC Anesthesiology 2021 21:124
  4. Respiratory compromise (RC) including hypoxia and hypoventilation is likely to be missed in the postoperative period. Integrated pulmonary index (IPI) is a comprehensive respiratory parameter evaluating ventil...

    Authors: Yasutoshi Kuroe, Yuko Mihara, Shuji Okahara, Kenzo Ishii, Tomoyuki Kanazawa and Hiroshi Morimatsu
    Citation: BMC Anesthesiology 2021 21:123
  5. This study compared the effects of premedication with different doses of aminophylline on the recovery profile after general anaesthesia.

    Authors: Samaa A. Kasim, Mahmoud Hussein Bahr, Mohamed Abdelkader and Doaa Abu Elkassim Rashwan
    Citation: BMC Anesthesiology 2021 21:122
  6. Orthopedic surgery for cervical torticollis poses potential threat to airway management both in tracheal intubation and extubation. Klippel-Feil syndrome (KFS) is a complex syndrome of osseous and visceral ano...

    Authors: Xiaoqing Zhang, Jun Wang, Yajie Liu, Zhengqian Li and Bin Han
    Citation: BMC Anesthesiology 2021 21:121
  7. In this study, we explored the utility of intravenous opioid rescue analgesia in the post anesthesia care unit (PACU-OpResc) as a single marker of thoracic epidural analgesia (TEA) failure and evaluated the re...

    Authors: Nadav Levy, Peter Santer, Liana Zucco, Sarah Nabel, Galina Korsunsky and Satya Krishna Ramachandran
    Citation: BMC Anesthesiology 2021 21:120
  8. Patient blood management programs should be applied to the pediatric population, but little is known about the current transfusion practice of pediatric burn injury patients. This retrospective study was perfo...

    Authors: Eva Wittenmeier, Astor Katharina, Irene Schmidtmann, Eva-Verena Griemert, Marc Kriege, Tatjana König and Pirlich Nina
    Citation: BMC Anesthesiology 2021 21:118
  9. Adams-Oliver syndrome is characterized by the combination of congenital scalp defects and terminal transverse limb defects. In some instances, cardiovascular malformations and orofacial malformations have been...

    Authors: Edwin Suarez, Mia J. Bertoli, Jean Daniel Eloy and Shridevi Pandya Shah
    Citation: BMC Anesthesiology 2021 21:117
  10. The intrathecal hyperbaric bupivacaine dosage for cesarean section is difficult to predetermine. This study aimed to develop a decision-support model using a machine-learning algorithm for assessing intratheca...

    Authors: Chang-na Wei, Li-ying Wang, Xiang-yang Chang and Qing-he Zhou
    Citation: BMC Anesthesiology 2021 21:116
  11. The current coronavirus infectious disease 2019 (COVID-19) pandemic has caused unexpected pressure on medical supplies, interrupting supply chains and increasing prices. The supply of antiviral filters which f...

    Authors: Ruth Shaylor, Mathew Francis, Esther Shaylor, Solomon Dadia and Barak Cohen
    Citation: BMC Anesthesiology 2021 21:115
  12. Enhanced recovery protocols optimize pain control via multimodal approaches that include transversus abdominis plane (TAP) block. The aim of this study was to evaluate the effect of preoperative vs. postoperat...

    Authors: Richard Kalu, Peter Boateng, Lauren Carrier, Jaime Garzon, Amy Tang, Craig Reickert and Amalia Stefanou
    Citation: BMC Anesthesiology 2021 21:114
  13. Bleeding after thyroidectomy occurs due to violent coughing during emergence. Dexmedetomidine is helpful for the smooth emergence and suppression of cough. The purpose of the present study was to compare the e...

    Authors: Sang Hun Kim, Yoo Seok Kim, Seongcheol Kim and Ki Tae Jung
    Citation: BMC Anesthesiology 2021 21:113
  14. Airway management is one of the most important techniques in anesthesia practice and inappropriate airway management is related with airway injury, brain hypoxia, and even death. The patients with cervical spo...

    Authors: Yang Zhou, Yongzheng Han, Zhengqian Li, Yuqing Zhao, Ning Yang, Taotao Liu, Min Li, Jun Wang, Xiangyang Guo and Mao Xu
    Citation: BMC Anesthesiology 2021 21:111
  15. Blood transfusion can cause immunosuppression and lead to worse outcomes in patients with digestive tract malignancies; however, the specific mechanism behind this is not completely understood. One theory is t...

    Authors: Yajun Liu, Junzhi Sun, Yun Xia, Michael R. Lyaker and Jianshe Yu
    Citation: BMC Anesthesiology 2021 21:110
  16. Hypertonic saline solution has been frequently utilized in clinical practice. However, due to the nonphysiological osmolality, hypertonic saline infusion usually induces local vascular pain. We conducted this ...

    Authors: Zhiping Song, Shibiao Chen, Yang Zhang, Xiaoyun Shi, Na Zhao and Zhengyu Liao
    Citation: BMC Anesthesiology 2021 21:109
  17. Highly structured electroencephalography (EEG) oscillations can occur in adults during etomidate-induced general anesthesia, but the link between these two phenomena is poorly understood. Therefore, in the pre...

    Authors: Lei Zhang, Shunqin Fan, Jiawei Zhang, Kun Fang, Lei Wang, Yuanyuan Cao, Lijian Chen, Xuesheng Liu and Erwei Gu
    Citation: BMC Anesthesiology 2021 21:108
  18. We assessed whether a postoperative bilateral, ultrasound-guided, posterior transversus abdominis plane (TAP) block could reduce 24 h rescue tramadol requirement compared with placebo in patients undergoing el...

    Authors: Yang Zhao, Han-Ying Zhang, Zong-Yi Yuan, Yi Han, Yi-Rong Chen, Qi-lin Liu and Tao Zhu
    Citation: BMC Anesthesiology 2021 21:107
  19. Bronchoscopy treatments of central airway obstruction (CAO) under general anesthesia are high-risky procedures, and posing a giant challenge to the anesthesiologists. We summarized and analyzed our clinical ex...

    Authors: Jing-Jin Li, Nan Li, Wei-Jia Ma, Ming-Xue Bao, Zi-Yang Chen and Zheng-Nian Ding
    Citation: BMC Anesthesiology 2021 21:106
  20. Intraoperative brain function monitoring with processed electroencephalogram (EEG) indices, such as the bispectral index (BIS) and patient state index (PSI), may improve characterization of the depth of sedati...

    Authors: James Harvey Jones, Vinay Ravikumar Nittur, Neal Fleming and Richard L. Applegate II
    Citation: BMC Anesthesiology 2021 21:105
  21. Myocardial ischemia-reperfusion injury (MIRI) is the most common cause of death worldwide. The NOD-, LRR- and pyrin domain-containing protein 3 (NLRP3) inflammasome plays an important role in the inflammatory ...

    Authors: Yaru Huang, Xiaotong Sun, Zhaodong Juan, Rui Zhang, Ruoguo Wang, Shuqi Meng, Jiajia Zhou, Yan Li, Keyou Xu and Keliang Xie
    Citation: BMC Anesthesiology 2021 21:104

    The Correction to this article has been published in BMC Anesthesiology 2021 21:141

  22. At present, low-concentration carbohydrate is rarely used in minor trauma surgery, and its clinical efficacy is unknown. The aim of the study was to evaluate the effect of preoperative oral low-concentration c...

    Authors: Shun Wang, Peng-fei Gao, Xiao Guo, Qi Xu, Yun-feng Zhang, Guo-qiang Wang and Jing-yan Lin
    Citation: BMC Anesthesiology 2021 21:103
  23. Laryngeal mask airways (LMA) are commonly used for airway management. Complications with this device are rare. However, when they do occur, there is a high risk for respiratory problems, necessitating early di...

    Authors: Hervé Vanden Eede, Elizabeth Norris, Michaël Torfs and Olivier Vanderveken
    Citation: BMC Anesthesiology 2021 21:102
  24. This study explored the comparison of the thermal insulation effect of incubator to infusion thermometer in laparoscopic hysterectomy.

    Authors: Guanyu Yang, Zefei Zhu, Hongyu Zheng, Shifeng He, Wanyue Zhang and Zhentao Sun
    Citation: BMC Anesthesiology 2021 21:101
  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ting Zheng, Bin Hu, Chun-ying Zheng, Feng-yi Huang, Fei Gao and Xiao-chun Zheng
    Citation: BMC Anesthesiology 2021 21:99

    The original article was published in BMC Anesthesiology 2021 21:75

  26. Ultrasound-guided parasternal intercostal nerve block is rarely used for postoperative analgesia, and its value remains unclear. This study aimed to evaluate the effectiveness of ultrasound-guided parasternal ...

    Authors: Hexiang Chen, Wenqin Song, Wei Wang, Yawen Peng, Chunchun Zhai, Lihua Yao and Zhongyuan Xia
    Citation: BMC Anesthesiology 2021 21:98
  27. Confocal laser endomicroscopy (CLE) has advantages in detecting gastric neoplastic lesions, meanwhile it requires strict patient cooperation. Sedation could improve patient cooperation and quality of endoscopy...

    Authors: Lihua Chu, Jialian Zhao, Cheng Sheng, Min Yue, Feifei Wang, Shengwen Song, Baoli Cheng, Guohao Xie and Xiangming Fang
    Citation: BMC Anesthesiology 2021 21:97
  28. The cumbersome program and the shortage of commercial solution hindered the regular application of regional citrate anticoagulation (RCA). It is urgent to simplify the protocol using only commercial preparatio...

    Authors: Yan Shi, Han-Yu Qin, Jin-Min Peng, Xiao-Yun Hu and Bin Du
    Citation: BMC Anesthesiology 2021 21:96
  29. Pneumoperitoneum and Trendelenburg position in laparoscopic surgeries could contribute to postoperative pulmonary dysfunction. In recent years, intraoperative lung-protective mechanical ventilation (LPV) has b...

    Authors: Trung Kien Nguyen, Viet Luong Nguyen, Truong Giang Nguyen, Duc Hanh Mai, Ngoc Quynh Nguyen, The Anh Vu, Anh Nguyet Le, Quang Huy Nguyen, Chi Tue Nguyen and Dang Thu Nguyen
    Citation: BMC Anesthesiology 2021 21:95
  30. Oropharyngeal airways are used both to facilitate airway patency during mask ventilation as well as conduits for flexible scope intubation, though none excel at both. A novel device, the Articulated Oral Airwa...

    Authors: Ron O. Abrons, Patrick Ten Eyck and Isaac D. Sheffield
    Citation: BMC Anesthesiology 2021 21:94
  31. Calcium increases the probability of transmitter release at the neuromuscular junction. It is not known whether there is a dose-dependent relationship between the dosage of calcium gluconate and the probabilit...

    Authors: So Ron Choi, Jeong Ho Kim, Kyung Hyun Lee and Sang Yoong Park
    Citation: BMC Anesthesiology 2021 21:93
  32. Intravenous bolus injection of fentanyl has been frequently reported to be associated with cough reflex during patient anesthesia. However, the search for the most effective protocol continues. This study aime...

    Authors: Laleh Dehghanpisheh, Mohammadhossein Eghbal, Fatemeh Bagheri Baravati and Pooya Vatankhah
    Citation: BMC Anesthesiology 2021 21:92
  33. Lidocaine and magnesium sulfate have become increasingly utilized in general anesthesia. The present study evaluated the effects of these drugs, isolated or combined, on hemodynamic parameters as well as on th...

    Authors: Waynice N Paula-Garcia, Gustavo H Oliveira-Paula, Hans Donald de Boer and Luis Vicente Garcia
    Citation: BMC Anesthesiology 2021 21:91
  34. Achieving optimal analgesia with few side effects is the goal of pain management after cesarean delivery. Intrathecal (IT) morphine is the current standard but ultrasound-guided quadratus lumborum block (QLB) ...

    Authors: Pawinee Pangthipampai, Sukanya Dejarkom, Suppachai Poolsuppasit, Choopong Luansritisakul and Suwida Tangchittam
    Citation: BMC Anesthesiology 2021 21:90
  35. Many patients complain of pain following laparoscopic surgery. Clinicians have used ultrasound-guided posterior transversus abdominis plane block (TAPB) and rectus sheath block (RSB) for multimodal analgesia a...

    Authors: Min Liang, Xia Xv, Chunguang Ren, Yongxing Yao and Xiujuan Gao
    Citation: BMC Anesthesiology 2021 21:89
  36. Opioid-induced respiratory depression is common on the general care floor. However, the clinical and economic burden of respiratory depression is not well-described. The PRediction of Opioid-induced respirator...

    Authors: Ashish K. Khanna, Leif Saager, Sergio D. Bergese, Carla R. Jungquist, Hiroshi Morimatsu, Shoichi Uezono, Lian Kah Ti, Roy Soto, Wei Jiang and Wolfgang Buhre
    Citation: BMC Anesthesiology 2021 21:88
  37. Waste anesthetic gases (WAGs) leaked from new-type halogenated inhalational anesthetics such as sevoflurane have been were reported to pose a risk for the health of operating room personnel. The effects of WAG...

    Authors: Zhimin Ji, Wanjun Wu, Fan Zhou, Junfang Hu, Qiuping Xu, Weibin Yang, Xueyong Peng, Xinguo Wang, Cheng Zhang and Li Li
    Citation: BMC Anesthesiology 2021 21:87
  38. To investigate the optimal target e of lactate kinetics at different time during the resuscitation, the factors that influence whether the kinetics achieve the goals, and the clinical implications of different...

    Authors: Bo Tang, Longxiang Su, Dongkai Li, Ye Wang, Qianqian Liu, Guangliang Shan, Yun Long, Dawei Liu and Xiang Zhou
    Citation: BMC Anesthesiology 2021 21:86
  39. Current principles of postoperative pain management are primarily based on the types and extent of surgical intervention. This clinical study measured patient’s self-anticipated pain score before surgery, and ...

    Authors: Wei-Shu Chang, Yi-Ting Hsieh, Moa-Chu Chen, Shu-Ching Chang, Tzu-Shan Chen, Yun-Chi Chang, Yu-Chuan Tsai and Chen-Fuh Lam
    Citation: BMC Anesthesiology 2021 21:85
  40. It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary obje...

    Authors: Guido Mazzinari, Ary Serpa Neto, Sabrine N. T. Hemmes, Goran Hedenstierna, Samir Jaber, Michael Hiesmayr, Markus W. Hollmann, Gary H. Mills, Marcos F. Vidal Melo, Rupert M. Pearse, Christian Putensen, Werner Schmid, Paolo Severgnini, Hermann Wrigge, Oscar Diaz Cambronero, Lorenzo Ball…
    Citation: BMC Anesthesiology 2021 21:84
  41. The mechanisms of trauma induced coagulopathy (TIC) are considered multifactorial. Amongst others, however, shedding of the endothelial glycocalyx resulting in increased concentrations of glycocalyx fragments ...

    Authors: Martin W. Britten, Laura Lümers, Kenji Tominaga, Jürgen Peters and Daniel Dirkmann
    Citation: BMC Anesthesiology 2021 21:83
  42. Authors: Lukas M. Löffel, Dominique Engel and Patrick Y. Wuethrich
    Citation: BMC Anesthesiology 2021 21:81

    The Correspondence to this article has been published in BMC Anesthesiology 2021 21:82

    The original article was published in BMC Anesthesiology 2020 20:291

  43. Metabolic status can be impacted by general anesthesia and surgery. However, the exact effects of general anesthesia and surgery on systemic metabolome remain unclear, which might contribute to postoperative o...

    Authors: Yiyong Wei, Donghang Zhang, Jin Liu, Mengchan Ou, Peng Liang, Yunxia Zuo and Cheng Zhou
    Citation: BMC Anesthesiology 2021 21:80
  44. Acute postoperative pain plays an important role in the perioperative neurocognitive disorders (PND). The pathogenesis of PND is still unknown, but it is generally believed that peripheral and central nervous ...

    Authors: Yu-fan Zhao, Hui-wen Yang, Ting-shun Yang, Wenxiu Xie and Zhong-hua Hu
    Citation: BMC Anesthesiology 2021 21:79
  45. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Furaha Nzanzu Blaise Pascal, Agnes Malisawa, Andreas Barratt-Due, Felix Namboya and Gregor Pollach
    Citation: BMC Anesthesiology 2021 21:78

    The original article was published in BMC Anesthesiology 2021 21:60

  46. The complexity of extracorporeal membrane oxygenation (ECMO) techniques continues to evolve. Different cannulation methods and configurations have been proposed as a response to a challenging cardiovascular an...

    Authors: Jose R. Navas-Blanco, Sofia A. Lifgren, Roman Dudaryk, Jeffrey Scott, Matthias Loebe and Ali Ghodsizad
    Citation: BMC Anesthesiology 2021 21:77

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