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  1. Content type: Study protocol

    The incidence of intraoperative awareness with explicit recall is 1-2/1000 cases in the United States. The Bispectral Index monitor is an electroencephalographic method of assessing anesthetic depth that has b...

    Authors: George A Mashour, Kevin K Tremper and Michael S Avidan

    Citation: BMC Anesthesiology 2009 9:7

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  2. Content type: Research article

    Monitoring of cardiac output and blood pressure are standard procedures in critical care medicine. Traditionally, invasive techniques like pulmonary artery catheter (PAC) and arterial catheters are widely used...

    Authors: John F Stover, Reto Stocker, Renato Lenherr, Thomas A Neff, Silvia R Cottini, Bernhard Zoller and Markus Béchir

    Citation: BMC Anesthesiology 2009 9:6

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  3. Content type: Research article

    Sevoflurane has been demonstrated to vasodilate the foeto-placental vasculature. We aimed to determine the contribution of modulation of potassium and calcium channel function to the vasodilatory effect of sev...

    Authors: James Jarman, Chrisen H Maharaj, Brendan D Higgins, Rachel F Farragher, Christopher D Laffey, Noel M Flynn and John G Laffey

    Citation: BMC Anesthesiology 2009 9:4

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  4. Content type: Research article

    Prolonged sedation is common in mechanically ventilated patients and is associated with increased morbidity and mortality. We sought to determine the diagnostic value of head computed tomography (CT) in mechan...

    Authors: Jay S Balachandran, Mairaj Jaleel, Manu Jain, Niraj Mahajan, Ravi Kalhan, Rajesh Balagani, Helen K Donnelly, Eugene Greenstein and Gökhan M Mutlu

    Citation: BMC Anesthesiology 2009 9:3

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  5. Content type: Research article

    Sub-Tenon's anaesthetic is effective and reliable in producing both akinesia and anaesthesia for cataract surgery. Our clinical experience indicates that it is sometimes necessary when absolute akinesia is req...

    Authors: Ehtesham I Khan, Jawad Mustafa, John McAdoo and George Shorten

    Citation: BMC Anesthesiology 2009 9:2

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  6. Content type: Research article

    Even the best cancer surgery is usually associated with minimal residual disease. Whether these remaining malignant cells develop into clinical recurrence is at least partially determined by adequacy of host d...

    Authors: Edith Fleischmann, Corinna Marschalek, Katja Schlemitz, Jarrod E Dalton, Thomas Gruenberger, Friedrich Herbst, Andrea Kurz and Daniel I Sessler

    Citation: BMC Anesthesiology 2009 9:1

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  7. Content type: Technical advance

    The Contact Heat Evoked Potential Stimulator (CHEPS) utilises rapidly delivered heat pulses with adjustable peak temperatures to stimulate the differential warm/heat thresholds of receptors expressed by Aδ and...

    Authors: Katherine Roberts, Anastasia Papadaki, Carla Gonçalves, Mary Tighe, Duncan Atherton, Ravikiran Shenoy, Donald McRobbie and Praveen Anand

    Citation: BMC Anesthesiology 2008 8:8

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  8. Content type: Research article

    Although the minimization of the applied tidal volume (VT) during high-frequency oscillatory ventilation (HFOV) reduces the risk of alveolar shear stress, it can also result in insufficient CO2-elimination with s...

    Authors: Ralf M Muellenbach, Julian Kuestermann, Markus Kredel, Amélie Johannes, Ulrike Wolfsteiner, Frank Schuster, Christian Wunder, Peter Kranke, Norbert Roewer and Jörg Brederlau

    Citation: BMC Anesthesiology 2008 8:7

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  9. Content type: Research article

    Fenoldopam mesylate, a selective dopamine1-receptor agonist, is used by intravenous infusion to treat hypertension in adults. Fenoldopam is not approved by the FDA for use in children; reports describing its u...

    Authors: Gregory B Hammer, Susan T Verghese, David R Drover, Myron Yaster and Joseph R Tobin

    Citation: BMC Anesthesiology 2008 8:6

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  10. Content type: Research article

    Intrathecal (IT) morphine provides excellent post-operative analgesia, but causes multiple side effects including nausea and vomiting (PONV), pruritus and respiratory depression, particularly at higher doses. ...

    Authors: Patrick Hassett, Bilal Ansari, Pachaimuthu Gnanamoorthy, Brian Kinirons and John G Laffey

    Citation: BMC Anesthesiology 2008 8:5

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  11. Content type: Research article

    The Zeus® (Dräger, Lübeck, Germany), an automated closed-circuit anesthesia machine, uses high fresh gas flows (FGF) to wash-in the circuit and the lungs, and intermittently flushes the system to remove unwanted ...

    Authors: Sofie De Cooman, Nathalie De Mey, Bram BC Dewulf, Rik Carette, Thierry Deloof, Maurice Sosnowski, Andre M De Wolf and Jan FA Hendrickx

    Citation: BMC Anesthesiology 2008 8:4

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  12. Content type: Research article

    Intermittent measurement of cardiac output may be performed using a lithium dilution technique (LiDCO). This can then be used to calibrate a pulse power algorithm of the arterial waveform which provides a cont...

    Authors: Maurizio Cecconi, Jayne Fawcett, R Michael Grounds and Andrew Rhodes

    Citation: BMC Anesthesiology 2008 8:3

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  13. Content type: Technical advance

    Gas chromatography (GC) has often been considered the most accurate method to measure the concentration of inhaled anesthetic vapors. However, infrared (IR) gas analysis has become the clinically preferred mon...

    Authors: Jan FA Hendrickx, Hendrikus JM Lemmens, Rik Carette, Andre M De Wolf and Lawrence J Saidman

    Citation: BMC Anesthesiology 2008 8:2

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  14. Content type: Research article

    Current analgesics have drawbacks such as delays in acquisition, lag-times for effect, and side effects. We recently presented a preliminary report of a new analgesic method involving a two-minute sciatic nerv...

    Authors: Jiman He, Bin Wu, Xianrong Jiang, Fenglin Zhang, Tao Zhao and Wenlon Zhang

    Citation: BMC Anesthesiology 2008 8:1

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  15. Content type: Research article

    Several techniques have been discussed as alternatives to the intermittent bolus thermodilution cardiac output (COPAC) measurement by the pulmonary artery catheter (PAC). However, these techniques usually require...

    Authors: Christopher Prasser, Sylvia Bele, Cornelius Keyl, Stefan Schweiger, Benedikt Trabold, Matthias Amann, Julia Welnhofer and Christoph Wiesenack

    Citation: BMC Anesthesiology 2007 7:9

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  16. Content type: Research article

    In addition to mortality, Health Related Quality of Life (HRQOL) has increasingly been claimed as an important outcome variable. The aim of this study was to assess HRQOL and independence in activities of dail...

    Authors: Fernando J Abelha, Cristina C Santos, Paula C Maia, Maria A Castro and Henrique Barros

    Citation: BMC Anesthesiology 2007 7:8

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  17. Content type: Research article

    Gabapentin is an antiepileptic drug used in a variety of chronic pain conditions. Increasing numbers of randomized trials indicate that gabapentin is effective as a postoperative analgesic. This procedure-spec...

    Authors: Ole Mathiesen, Steen Møiniche and Jørgen B Dahl

    Citation: BMC Anesthesiology 2007 7:6

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  18. Content type: Research article

    Experience suggests that patients with alcohol and other drug use disorders (AOD) are commonly cared for in our intensive care units (ICU's) and require more sedation. We sought to determine the impact of AOD ...

    Authors: Marjolein de Wit, Sau Yin Wan, Sujoy Gill, Wendy I Jenvey, Al M Best, Judith Tomlinson and Michael F Weaver

    Citation: BMC Anesthesiology 2007 7:3

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  19. Content type: Case report

    We report a case of severe upper airway obstruction due to a retropharyngeal hematoma that presented nearly one day after a precipitating traumatic injury. Retropharyngeal hematomas are rare, but may cause lif...

    Authors: Laurie W Lazott, John A Ponzo, Rudolph B Puana, Katie S Artz, David P Ciceri and William C Culp Jr

    Citation: BMC Anesthesiology 2007 7:2

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  20. Content type: Research article

    We have developed a two-step procedure for preparing the skin before peripheral venous catheter (PVC) insertions. This procedure involves two successive swabbings with wipes soaked in alcoholic antiseptic. We ...

    Authors: Nathalie L van der Mee-Marquet

    Citation: BMC Anesthesiology 2007 7:1

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  21. Content type: Research article

    Despite the presence of a plethora of publications on the prevention of postoperative nausea and vomiting (PONV) only little is known how to treat established symptoms. Besides the high effort of performing th...

    Authors: Leopold HJ Eberhart, Silke Frank, Henning Lange, Astrid M Morin, André Scherag, Hinnerk Wulf and Peter Kranke

    Citation: BMC Anesthesiology 2006 6:14

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  22. Content type: Technical advance

    Anesthetic sensitivity is determined by the interaction of multiple genes. Hence, a dissection of genetic contributors would be aided by precise and high throughput behavioral screens. Traditionally, anestheti...

    Authors: Yi Sun, Jingqiu Chen, Gregory Pruckmayr, James E Baumgardner, David M Eckmann, Roderic G Eckenhoff and Max B Kelz

    Citation: BMC Anesthesiology 2006 6:13

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  23. Content type: Research article

    A considerable number of patients require opioids during recovery after laparoscopic sterilization. This implies nausea, dizziness and sedation and increases the number of unplanned admissions. Gabapentin has ...

    Authors: Jens Bartholdy, Karen L Hilsted, Nils C Hjortsoe, Jens Engbaek and Joergen B Dahl

    Citation: BMC Anesthesiology 2006 6:12

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  24. Content type: Case report

    Systemic sclerosis (SSc), a progressive disease characterized by excessive accumulation of connective tissue components. Although most patients have long survival, some of them progress rapidly to death. Pulmo...

    Authors: Gülcan Erk, Vildan taşpınar, Ferah Dönmez and Dilşen örnek

    Citation: BMC Anesthesiology 2006 6:11

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  25. Content type: Research article

    Epidural anaesthesia is used extensively for cardiothoracic and vascular surgery in some centres, but not in others, with argument over the safety of the technique in patients who are usually extensively antic...

    Authors: Wilhelm Ruppen, Sheena Derry, Henry J McQuay and R Andrew Moore

    Citation: BMC Anesthesiology 2006 6:10

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  26. Content type: Research article

    To study the effect of administration of tranexamic acid on the use of blood and blood products, return to theatre for post-operative bleeding and the length of intensive care stay after primary cardiac surger...

    Authors: Alain Vuylsteke, Palanikumar Saravanan, Caroline Gerrard and Fay Cafferty

    Citation: BMC Anesthesiology 2006 6:9

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  27. Content type: Research article

    To compare the effect of a sustained inflation followed by an incremental mean airway pressure trial during conventional and high-frequency oscillatory ventilation on oxygenation and hemodynamics in a large po...

    Authors: Ralf M Muellenbach, Markus Kredel, Bernd Zollhoefer, Christian Wunder, Norbert Roewer and Joerg Brederlau

    Citation: BMC Anesthesiology 2006 6:8

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  28. Content type: Research article

    Kinetics of inhaled agents are often described by physiological models. However, many pharmacokinetic concepts, such as context-sensitive half-times, have been developed for drugs described by classical compar...

    Authors: Jan FA Hendrickx, Hendrikus JM Lemmens and Steven L Shafer

    Citation: BMC Anesthesiology 2006 6:7

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  29. Content type: Research article

    When patients are asked what they find most anxiety provoking about having surgery, the top concerns almost always include postoperative nausea and vomiting (PONV). Only until recently have there been any publ...

    Authors: Alex Macario, Louis Claybon and Joseph V Pergolizzi

    Citation: BMC Anesthesiology 2006 6:6

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  30. Content type: Research article

    Thoracotomy is associated with severe pain that may persist for years. Acupuncture is a complementary therapy with a proven role in pain control. A randomized trial showed that acupuncture was effective in con...

    Authors: Andrew J Vickers, Valerie W Rusch, Vivek T Malhotra, Robert J Downey and Barrie R Cassileth

    Citation: BMC Anesthesiology 2006 6:5

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  31. Content type: Research article

    This animal study was conducted to assess the combined effects of high frequency oscillatory ventilation (HFOV) and prone positioning on pulmonary gas exchange and hemodynamics.

    Authors: Joerg Brederlau, Ralf Muellenbach, Markus Kredel, Clemens Greim and Norbert Roewer

    Citation: BMC Anesthesiology 2006 6:4

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  32. Content type: Research article

    Induction of the COX-2 isoenzyme appears to play a major role in the genesis of central sensitization after nociceptive stimulation. This study aimed to investigate the efficacy of a single, oral dose of the s...

    Authors: David Burns, Lindsay Hill, Michael Essandoh, Tomasz M Jarzembowski, H Gregg Schuler and Piotr K Janicki

    Citation: BMC Anesthesiology 2006 6:3

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  33. Content type: Research article

    Chronic alveolar hypoxia results in sustained arterial constriction, and increase in pulmonary vascular resistance leading to pulmonary artery hypertension (PAHT). The aim of this study was to investigate the ...

    Authors: Nazinigouba Ouédraogo, Boutchi Mounkaïla, Huguette Crevel, Roger Marthan and Etienne Roux

    Citation: BMC Anesthesiology 2006 6:2

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  34. Content type: Research article

    Cervicogenic headache (CEH) is a unilateral headache localised in the neck or occipital region, projecting to the frontal and temporal regions. Since the pathogenesis of this syndrome appears to have an anatom...

    Authors: Sara RS Haspeslagh, Hans A Van Suijlekom, Inge E Lamé, Alfons GH Kessels, Maarten van Kleef and Wim EJ Weber

    Citation: BMC Anesthesiology 2006 6:1

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  35. Content type: Research article

    Postoperative epidural fibrosis may contribute to between 5% to 60% of the poor surgical outcomes following decompressive surgery. Correlations have been reported between epidural scarring and radicular pain, ...

    Authors: Laxmaiah Manchikanti, Mark V Boswell, Jose J Rivera, Vidya Sagar Pampati, Kim S Damron, Carla D McManus, Doris E Brandon and Sue R Wilson

    Citation: BMC Anesthesiology 2005 5:10

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  36. Content type: Debate

    Surgical treatment and its consequences expose patients to stress, and here we investigated the importance of the psychological component of postoperative pain based on reports in the clinical literature.

    Authors: Paul Svedman, Martin Ingvar and Torsten Gordh

    Citation: BMC Anesthesiology 2005 5:9

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  37. Content type: Research article

    Malignant hyperthermia (MH) is triggered by halogenated anaesthetics and depolarising muscle relaxants, leading to an uncontrolled hypermetabolic state of skeletal muscle. An uncontrolled sarcoplasmic Ca2+ releas...

    Authors: Frank Schuster, Rainer Müller, Edmund Hartung, Norbert Roewer and Martin Anetseder

    Citation: BMC Anesthesiology 2005 5:8

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  38. Content type: Research article

    Inadvertent hypothermia is not uncommon in the immediate postoperative period and it is associated with impairment and abnormalities in various organs and systems that can lead to adverse outcomes. The aim of ...

    Authors: Fernando J Abelha, Maria A Castro, Aida M Neves, Nuno M Landeiro and Cristina C Santos

    Citation: BMC Anesthesiology 2005 5:7

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  39. Content type: Research article

    Desflurane and enflurane have been reported to produce substantial amounts of carbon monoxide (CO) in desiccated sodalime. Isoflurane is said to produce less CO and sevoflurane and halothane should produce no ...

    Authors: Christiaan Keijzer, Roberto SGM Perez and Jaap J De Lange

    Citation: BMC Anesthesiology 2005 5:6

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  40. Content type: Research article

    Propofol is widely used for both short-term anesthesia and long-term sedation. It has unusual pharmacokinetics because of its high lipid solubility. The standard approach to describing the pharmacokinetics is ...

    Authors: David G Levitt and Thomas W Schnider

    Citation: BMC Anesthesiology 2005 5:4

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  41. Content type: Research article

    The possibility exists for major complications to occur when individuals are intoxicated with alcohol prior to anesthetization. Halothane is an anesthetic that can be metabolized by the liver into a highly rea...

    Authors: Geoffrey M Thiele, Gary E Hill, Jacqueline A Pavlik, Thomas L Freeman, Dean J Tuma, Michael J Duryee and Lynell W Klassen

    Citation: BMC Anesthesiology 2005 5:3

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  42. Content type: Technical advance

    Despite preclinical evidence suggesting a synergistic interaction between ketamine and opioids promoting analgesia, several clinical trials have not identified dosing regimens capable of eliciting a benefit in...

    Authors: Adam P Tucker, Yong Ik Kim, Raymond Nadeson and Colin S Goodchild

    Citation: BMC Anesthesiology 2005 5:2

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  43. Content type: Research article

    Although several potential risk factors have been discussed, risk factors associated with bacterial colonization or even infection of catheters used for regional anaesthesia are not very well investigated.

    Authors: Astrid M Morin, Klaus M Kerwat, Martina Klotz, Roswitha Niestolik, Veronika E Ruf, Hinnerk Wulf, Stefan Zimmermann and Leopold HJ Eberhart

    Citation: BMC Anesthesiology 2005 5:1

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  44. Content type: Research article

    Cuff pressure in endotracheal (ET) tubes should be in the range of 20–30 cm H2O. We tested the hypothesis that the tube cuff is inadequately inflated when manometers are not used.

    Authors: Papiya Sengupta, Daniel I Sessler, Paul Maglinger, Spencer Wells, Alicia Vogt, Jaleel Durrani and Anupama Wadhwa

    Citation: BMC Anesthesiology 2004 4:8

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