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  1. Postoperative complications occur frequently, despite progress in anesthetic pharmacology and surgical techniques. Although habits, such as alcohol and tobacco use, and mental health have been studied individu...

    Authors: Yoshinori Myoga, Haruhiko Manabe and Yoneatsu Osaki

    Citation: BMC Anesthesiology 2021 21:245

    Content type: Research

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  2. For the detection of cardiac surgery-associated acute kidney injury (CS-AKI), the performance of urine tissue inhibitor of metalloproteinase 2 insulin-like growth factor-binding protein 7 (TIMP2 IGFBP7) has ne...

    Authors: Karim Lakhal, Edith Bigot-Corbel, Emilie Sacchetto, Floris Chabrun, Thomas Senage, Lucile Figueres, Maxime Leroy, Arnaud Legrand and Bertrand Rozec

    Citation: BMC Anesthesiology 2021 21:244

    Content type: Research

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  3. Radical nephrectomy with thrombectomy is the mainstay treatment for patients with renal cell carcinoma with vena cava thrombus. But the procedure is full of challenge, with high incidence of major complication...

    Authors: Yi-Bin Hua, Xue Li and Dong-Xin Wang

    Citation: BMC Anesthesiology 2021 21:243

    Content type: Research

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  4. Evidence regarding the relationship between the type of anaesthesia and length of hospital stay is controversial. Therefore, the objective of this research was to investigate whether the type of anaesthesia wa...

    Authors: Xuan JI and Weiqi KE

    Citation: BMC Anesthesiology 2021 21:242

    Content type: Research

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  5. Central venous catheter (CVC) placement is a routine procedure but is potentially associated with severe complications. Relatively small studies investigated if the use of ultrasound is effective in bridging t...

    Authors: Alessandro De Cassai, Federico Geraldini, Laura Pasin, Annalisa Boscolo, Francesco Zarantonello, Martina Tocco, Chiara Pretto, Matteo Perona, Michele Carron and Paolo Navalesi

    Citation: BMC Anesthesiology 2021 21:241

    Content type: Research

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  6. Better protection can be provided during neurosurgery due to the establishment of somatosensory-evoked potential (SEP) and motor-evoked potential (MEP) monitoring technologies. However, some studies have showe...

    Authors: Bingbing Xiang, Shulan Jiao, Yulong Zhang, Lu Wang, Yuting Yao, Feng Yuan, Rui Chen and Qijun Zhou

    Citation: BMC Anesthesiology 2021 21:240

    Content type: Research

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  7. Preoxygenation and application of apneic oxygenation are standard to prevent patients from desaturation e.g. during emergency intubation. The time before desaturation occurs can be prolonged by applying high f...

    Authors: W. A. Wetsch, H. Herff, D. C. Schroeder, D. Sander, B. W. Böttiger and S. R. Finke

    Citation: BMC Anesthesiology 2021 21:239

    Content type: Research

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  8. Although general anesthetics depress spontaneous respiration, the comprehensive effect of general anesthetics on respiratory function remains unclear. We aimed to investigate the effects of general anesthetics...

    Authors: Xuechao Hao, Mengchan Ou, Yu Li and Cheng Zhou

    Citation: BMC Anesthesiology 2021 21:238

    Content type: Research

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  9. Uvulopalatopharyngoplasty(UPPP) is the most prevalent surgical treatment of obstructive sleep apnea, but postoperative pharyngeal pain may affect patient comfort. The enhanced recovery after surgery pathway ha...

    Authors: Fei Huang, Minxue Wang, Huixin Chen, Nan Cheng, Yanling Wang, Di Wu and Shaoli Zhou

    Citation: BMC Anesthesiology 2021 21:237

    Content type: Research

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  10. Primary graft dysfunction (PGD) is the main cause of death in the first 30 days after heart transplantation (HTX), accounting for approximately 40% of mortality. The study’s primary aim was to assess the incid...

    Authors: Anna Kędziora, Jacek Piątek, Hubert Hymczak, Grzegorz Wasilewski, Bartłomiej Guzik, Rafał Drwiła, Bogusław Kapelak, Dorota Sobczyk, Janusz Konstanty-Kalandyk and Karol Wierzbicki

    Citation: BMC Anesthesiology 2021 21:236

    Content type: Research

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  11. Nasal bleeding is the most common complication during nasotracheal intubation (NTI). To reduce nasal bleeding, the nasal mucosa is treated with vasoconstrictors (epinephrine [E] or tramazoline [T]) prior to NT...

    Authors: Aiji Sato-Boku, Yoshiki Sento, Yuji Kamimura, Eisuke Kako, Masahiro Okuda, Naoko Tachi, Yoko Okumura, Mayumi Hashimoto, Hiroshi Hoshijima, Fumihito Suzuki and Kazuya Sobue

    Citation: BMC Anesthesiology 2021 21:235

    Content type: Research

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  12. Postoperative nausea and vomiting (PONV) as a clinically most common postoperative complication requires multimodal antiemetic medications targeting at a wide range of neurotransmitter pathways. Lacking of neu...

    Authors: Nana Li, Lu Liu, Menghan Sun, Ruiliang Wang, Wenjie Jin, Cunming Liu and Youli Hu

    Citation: BMC Anesthesiology 2021 21:234

    Content type: Research

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  13. Peripheral injection of dexmedetomidine (DEX) has been widely used in regional anesthesia to prolong the duration of analgesia. However, the optimal perineural dose of DEX is still uncertain. It is important t...

    Authors: Hai Cai, Xing Fan, Pengjiu Feng, Xiaogang Wang and Yubo Xie

    Citation: BMC Anesthesiology 2021 21:233

    Content type: Research

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  14. Midazolam is frequently used for sedation during spinal anesthesia. However, external environmental factors, such as bright surgical lights, may hamper patient relaxation, which may lead to an increase in the ...

    Authors: Seon Woo Yoo, Min-Jong Ki, Dal Kim, Yu Jin Oh and Jeongwoo Lee

    Citation: BMC Anesthesiology 2021 21:232

    Content type: Research

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  15. To investigate the effects of different plasma target concentrations of remifentanil on the minimum alveolar concentration (MAC) for blocking adrenergic response (BAR) of sevoflurane in children with laparosco...

    Authors: Dan Wang, Juan Xu, Xiao-Lin Yang, Yan-Xia Guo, Ping-Ping Jiang and Guo-Yuan Zhang

    Citation: BMC Anesthesiology 2021 21:231

    Content type: Research Article

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  16. Citation: BMC Anesthesiology 2021 21:230

    Content type: Retraction Note

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  17. Whether epidural administered sufentanil combined with low-concentration ropivacaine affected labor progress as well as maternal and neonatal outcomes still remained unknown. The aim of this study was to asses...

    Authors: Le Zhang, Chengjie Xu and Yue Li

    Citation: BMC Anesthesiology 2021 21:229

    Content type: Research

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  18. Parathyroidectomy has been proposed as a method for reducing parathyroid hormone levels. We evaluated the effects of ultrasound-guided bilateral superficial cervical plexus block (BSCPB) on the quality of reco...

    Authors: Shenghong Hu, Teng Shu, Siqi Xu, Xia Ju, Shengbin Wang and Li Ma

    Citation: BMC Anesthesiology 2021 21:228

    Content type: Research Article

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  19. Down syndrome (DS) is associated with intellectual disability. DS patients may be unable to cooperate and often require general anesthesia even for minor surgeries. Rapid recovery significantly contributes to ...

    Authors: Emmanouil Gkliatis, Alexandros Makris and Chryssoula Staikou

    Citation: BMC Anesthesiology 2021 21:227

    Content type: Research

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  20. Hemodynamic instability is a frequent adverse effect following administration of dexmedetomidine (DMED). In this study, we evaluated the incidence of DMED-induced hemodynamic instability and its predictive fac...

    Authors: A Ram Doo, Hyungseok Lee, Seon Ju Baek and Jeongwoo Lee

    Citation: BMC Anesthesiology 2021 21:207

    Content type: Research

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  21. A comparison of different anesthetic techniques to evaluate short term outcomes has yet to be performed for patients undergoing outpatient knee replacements. The aim of this investigation was to compare short ...

    Authors: Mark C. Kendall, Alexander D. Cohen, Stephanie Principe-Marrero, Peter Sidhom, Patricia Apruzzese and Gildasio De Oliveira

    Citation: BMC Anesthesiology 2021 21:226

    Content type: Research

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  22. An increasing number of patients older than 80 years are undergoing anesthesia, but little information is available regarding pharmacodynamic effects of myorelaxants in this population. This study aims to comp...

    Authors: Denis Schmartz, Raouf Sghaier, Paul Bernard, Jean François Fils and Thomas Fuchs-Buder

    Citation: BMC Anesthesiology 2021 21:225

    Content type: Research

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  23. Many patients with acute respiratory distress syndrome (ARDS) suffer from cognitive impairment after hospital discharge. Different mechanisms have been implicated as potential causes for this impairment, inter...

    Authors: Jens Kamuf, Andreas Garcia Bardon, Alexander Ziebart, Robert Ruemmler, Johannes Schwab, Mobin Dib, Andreas Daiber, Serge C. Thal and Erik K. Hartmann

    Citation: BMC Anesthesiology 2021 21:224

    Content type: Research

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  24. Dexmedetomidine promotes normal sleep architecture; the drug also improves analgesia. We therefore tested the hypothesis that supplementing intravenous analgesia with dexmedetomidine reduces delirium in older ...

    Authors: Hong Hong, Da-Zhi Zhang, Mo Li, Geng Wang, Sai-Nan Zhu, Yue Zhang, Dong-Xin Wang and Daniel I. Sessler

    Citation: BMC Anesthesiology 2021 21:223

    Content type: Research

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  25. Continuous infusion of propofol has been used to achieve sedation in children. However, the relationship between the effect-site concentration (Ce) of propofol and sedation scale has not been previously examined....

    Authors: Young-Eun Jang, Sang-Hwan Ji, Ji-Hyun Lee, Eun-Hee Kim, Jin-Tae Kim and Hee-Soo Kim

    Citation: BMC Anesthesiology 2021 21:222

    Content type: Research

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  26. Spondylolisthesis is a common degenerative spinal deformity. At the level of spondylolisthesis, the anatomy of the interlaminar space may differ from normal spine, in which case optimal angle of the needle ins...

    Authors: Youngwon Kim, Seokha Yoo, Sun-Kyung Park, Hansu Bae, Young-Jin Lim and Jin-Tae Kim

    Citation: BMC Anesthesiology 2021 21:221

    Content type: Research

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  27. Malnutrition in intensive care unit (ICU) patients is associated with adverse clinical outcomes. The modified nutrition risk in the critically ill score (mNUTRIC) was proposed as an appropriate nutritional ass...

    Authors: Na Wang, Mei-Ping Wang, Li Jiang, Bin Du, Bo Zhu and Xiu-Ming Xi

    Citation: BMC Anesthesiology 2021 21:220

    Content type: Research

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  28. Circulatory failure frequently occurs after out-of-hospital cardiac arrest (OHCA) and is part of post-cardiac arrest syndrome (PCAS). The aim of this study was to investigate circulatory disturbances in PCAS ...

    Authors: Halvor Langeland, Daniel Bergum, Trond Nordseth, Magnus Løberg, Thomas Skaug, Knut Bjørnstad, Ørjan Gundersen, Nils-Kristian Skjærvold and Pål Klepstad

    Citation: BMC Anesthesiology 2021 21:219

    Content type: Research

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  29. Anterior cruciate ligament (ACL) reconstruction is an invasive surgical procedure for the knee. Quadruple nerve blocks including continuous femoral nerve block and single-injection sciatic, obturator, and late...

    Authors: Yuki Aoyama, Shinichi Sakura, Shoko Abe, Erika Uchimura and Yoji Saito

    Citation: BMC Anesthesiology 2021 21:218

    Content type: Research

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  30. Emergence delirium (ED) is common in pediatric anesthesia. This dissociative state in which the patient is confused from their surroundings and flailing can be self-injurious and traumatic for parents. Treatme...

    Authors: Adam C. Adler, Brian H. Nathanson and Arvind Chandrakantan

    Citation: BMC Anesthesiology 2021 21:217

    Content type: Research

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  31. The effects of circadian rhythms on drug metabolism and efficacy are being increasingly recognized. However, the extent to which they affect general anesthesia remains unclear. This study aims to investigate t...

    Authors: Jiang-hua Shen, Min Ye, Qian Chen, Yan Chen, Hai-lin Zhao, Ameena Khan, Bin Yi, Jiao-lin Ning, Kai-zhi Lu and Jian-teng Gu

    Citation: BMC Anesthesiology 2021 21:215

    Content type: Research

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  32. The dead space washout and provision of some level of positive airway pressure by nasal high-flow (NHF) cannula could improve the efficiency of ventilation, oxygenation and maintenance of the upper airway in p...

    Authors: Amorn Vijitpavan and Yanin Kooncharoensuk

    Citation: BMC Anesthesiology 2021 21:214

    Content type: Research

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  33. Sevoflurane (Sev) has been reported to inhibit cancer development, and sevoflurane treatment in cancers is implicated with the deregulation of specific non-coding RNAs (ncRNAs). This study aimed to investigate...

    Authors: Xiaofang Kang, Hongxia Li and Zaiwang Zhang

    Citation: BMC Anesthesiology 2021 21:213

    Content type: Research Article

    Published on:

  34. The mechanism of volatile anesthetics on vascular smooth muscle (VSM) contraction in the setting of diabetes mellitus (DM) remains unclear. The current study was designed to determine the effects of sevofluran...

    Authors: Shaozhong Yang, Yu Liu, Shanshan Huang, Feihong Jin and Feng Qi

    Citation: BMC Anesthesiology 2021 21:212

    Content type: Research

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  35. Postoperative nausea and vomiting and postoperative ileus are common after major digestive surgery and represent one of the significant problems in Acute Care Surgery.

    Authors: Valerio Cozza, Lorenzo Barberis, Gaia Altieri, Mario Donatelli, Gabriele Sganga and Antonio La Greca

    Citation: BMC Anesthesiology 2021 21:211

    Content type: Research

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  36. Caudal block is one of the most preferred regional anesthesia for sub-umbilical region surgeries in the pediatric population. However, few studies are available on caudal block performed in laparoscopic-assist...

    Authors: Zhixiong Lin, Yifan Fang, Lei Yan, Yu Lin, Mingkun Liu, Bing Zhang, Yuanbing He, Yong Shen, Dianming Wu and Longxin Zhang

    Citation: BMC Anesthesiology 2021 21:209

    Content type: Research Article

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  37. Lung separation may be achieved through the use of double lumen tubes or endobronchial blockers. The use of lung separation techniques carries the risk of airway injuries which range from minor complications l...

    Authors: Shuwen Oo, Rachel Hui Xuan Chia, Yue Li, Hari Kumar Sampath, Sophia Bee Leng Ang, Suresh Paranjothy, John Kit Chung Tam and Chang Chuan Melvin Lee

    Citation: BMC Anesthesiology 2021 21:208

    Content type: Case report

    Published on:

  38. Residual neuromuscular block at the end of surgery may compromise the patient’s safety. The risk of airway complications can be minimized through monitoring of neuromuscular function and reversal of neuromuscu...

    Authors: Ákos I. Fábián, Edömér Tassonyi, Vera Csernoch, Marianna Fedor, Tamás Sohajda, Lajos Szente and Béla Fülesdi

    Citation: BMC Anesthesiology 2021 21:206

    Content type: Research

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  39. Anesthesia leads to impairments in central and peripheral thermoregulatory responses. Inadvertent perioperative hypothermia is hence a common perioperative complication, and is associated with coagulopathy, in...

    Authors: Wenjun Koh, Murali Chakravarthy, Edgard Simon, Raveenthiran Rasiah, Somrat Charuluxananan, Tae-Yop Kim, Sophia T. H. Chew, Anselm Bräuer and Lian Kah Ti

    Citation: BMC Anesthesiology 2021 21:205

    Content type: Research

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  40. Cerebral ischemia/reperfusion injury (CIRI) is a complication of surgical procedure associated with high mortality. The protective effect of dexmedetomidine (DEX) on CIRI has been explored in previous works, y...

    Authors: Wenyi Liu, Cuihua Shao, Chuanshan Zang, Jian Sun, Min Xu and Yuna Wang

    Citation: BMC Anesthesiology 2021 21:203

    Content type: Research Article

    Published on:

  41. Administration of an optimal dose of anesthetic agent to ensure adequate depth of hypnosis with the lowest risk of adverse effects to the fetus is highly important in cesarean section. Sodium thiopental (STP) ...

    Authors: Golnar Sabetian, Farid Zand, Fatemeh Mirhadi, Mohammad Reza Hadavi, Elham Asadpour, Laleh Dehghanpisheh, Zeinabsadat Fattahi Saravi and Seyed Mostajab Razavi

    Citation: BMC Anesthesiology 2021 21:201

    Content type: Research

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  42. Lung protective ventilation with low tidal volume (TV) and increased positive end-expiratory pressure (PEEP) can have unfavorable effects on the cardiovascular system. We aimed to investigate whether lung prot...

    Authors: Sidse Høyer, Frank H. Mose, Peter Ekeløf, Jørgen B. Jensen and Jesper N. Bech

    Citation: BMC Anesthesiology 2021 21:200

    Content type: Research Article

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  43. A few studies have reported that administration of lidocaine and dexmedetomidine relieves the incidence of postoperative nausea and vomiting (PONV). We explored whether combined infusion of lidocaine plus dexm...

    Authors: Siqi Xu, Shengbin Wang, Shenghong Hu, Xia Ju, Qing Li and Yuanhai Li

    Citation: BMC Anesthesiology 2021 21:199

    Content type: Research

    Published on:

  44. Arytenoid dislocation is a rare laryngeal injury that may follow endotracheal intubation. We aimed to determine the incidence and risk factors for arytenoid dislocation after surgery under general anaesthesia.

    Authors: Eun-A Jang, Kyung Yeon Yoo, Seongheon Lee, Seung Won Song, Eugene Jung, Joungmin Kim and Hong-Beom Bae

    Citation: BMC Anesthesiology 2021 21:198

    Content type: Research

    Published on:

  45. Liposomal bupivacaine (LB) is a long-acting formulation of bupivacaine. The safety and efficacy of LB has been demonstrated across surgical procedures. However, pharmacokinetic (PK) parameters and safety of LB...

    Authors: Bernard MY Cheung, Pauline Yeung Ng, Ying Liu, Manman Zhou, Vincent Yu, Julia Yang and Natalie Q. Wang

    Citation: BMC Anesthesiology 2021 21:197

    Content type: Research

    Published on:

  46. Multifunction surveillance alerting systems have been found to be beneficial for the operating room and labor and delivery. This paper describes a similar system developed for in-hospital acute care environmen...

    Authors: Douglas A. Colquhoun, Ryan P. Davis, Theodore T. Tremper, Jenny J. Mace, Jan M. Gombert, William D. Sheldon, Joseph J. Connolly, Justin F. Adams and Kevin K. Tremper

    Citation: BMC Anesthesiology 2021 21:196

    Content type: Software

    Published on:

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