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  1. Liposomal bupivacaine (LB) is a long-acting formulation of bupivacaine. The safety and efficacy of LB has been demonstrated across surgical procedures. However, pharmacokinetic (PK) parameters and safety of LB...

    Authors: Bernard MY Cheung, Pauline Yeung Ng, Ying Liu, Manman Zhou, Vincent Yu, Julia Yang and Natalie Q. Wang

    Citation: BMC Anesthesiology 2021 21:197

    Content type: Research

    Published on:

  2. Multifunction surveillance alerting systems have been found to be beneficial for the operating room and labor and delivery. This paper describes a similar system developed for in-hospital acute care environmen...

    Authors: Douglas A. Colquhoun, Ryan P. Davis, Theodore T. Tremper, Jenny J. Mace, Jan M. Gombert, William D. Sheldon, Joseph J. Connolly, Justin F. Adams and Kevin K. Tremper

    Citation: BMC Anesthesiology 2021 21:196

    Content type: Software

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  3. Preterm neonates are at higher risk of developing inguinal hernia, and have an increased risk of perioperative adverse events. Laryngeal mask airway (LMA) is claimed to be associated to decreasing perioperativ...

    Authors: Miao-Pei Su, Ping-Yang Hu, Jao-Yu Lin, Shu-Ting Yang, Kuang-I Cheng and Chia-Heng Lin

    Citation: BMC Anesthesiology 2021 21:195

    Content type: Research Article

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  4. This study aims to investigate the risk factors of perioperative neurocognitive disorders (PNDs) mainly including postoperative cognitive dysfunction (POCD) in elderly patients with gastrointestinal tumors, an...

    Authors: Yong-Li Li, Hui-Fan Huang and Yuan Le

    Citation: BMC Anesthesiology 2021 21:193

    Content type: Research

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  5. Effective postoperative analgesia is needed to prevent the negative effects of postoperative pain on patient outcomes. To compare the effectiveness of hydromorphone hydrochloride and sufentanil, combined with ...

    Authors: Yongying Pan, Yimin Wang, Dongxu Lie, Di Liu, Xi Chen, Zeyan Wu, Liumei Chen, Huaizhen Wang, Liangming Peng, Huiying Liang, Xingrong Song and Baisong Zhao

    Citation: BMC Anesthesiology 2021 21:192

    Content type: Research Article

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  6. In the recent years, an increasing number of patients with multiple comorbidities (e.g. coronary artery disease, diabetes, hypertension) presents to the operating room. The clinical risk factors are accompanie...

    Authors: Volker Schick, Marc Boensch, Milan van Edig, Jonas Alfitian, Tülay Pola, Hannes Ecker, Falko Lindacher, Kija Shah-Hosseini, Wolfgang A. Wetsch, Bernhard Riedel and Robert Schier

    Citation: BMC Anesthesiology 2021 21:190

    Content type: Research

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  7. Cardiac output (CO) is a key measure of adequacy of organ and tissue perfusion, especially in critically ill or complex surgical patients. CO monitoring technology continues to evolve. Recently developed CO mo...

    Authors: Ramakrishna Mukkamala, Benjamin A. Kohl and Aman Mahajan

    Citation: BMC Anesthesiology 2021 21:189

    Content type: Research

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  8. Patients often suffer moderate or even severe pain after total hip arthroplasty; such pain seriously affects early postoperative recovery. This study aimed to investigate the analgesic efficacy of ultrasound-g...

    Authors: Qin Xia, Wenping Ding, Chao Lin, Jiayi Xia, Yahui Xu and Mengxing Jia

    Citation: BMC Anesthesiology 2021 21:188

    Content type: Research Article

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  9. Fluid extravasation from the shoulder compartment and subsequent absorption into adjacent soft tissue is a well-documented phenomenon in arthroscopic shoulder surgery. We aimed to determine if a qualitative di...

    Authors: Jason K. Panchamia, Ram Jagannathan, Bridget P. Pulos, Adam W. Amundson, Joaquin Sanchez-Sotelo, David P. Martin and Hugh M. Smith

    Citation: BMC Anesthesiology 2021 21:187

    Content type: Research

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  10. In line with aging populations and increased application of anesthesia and surgery, perioperative neurocognitive disorder (PND) has received growing attention worldwide. Considerable researches into PND are be...

    Authors: Xinning Mi, Xiaoxiao Wang, Ning Yang, Yongzheng Han, Yue Li, Taotao Liu, Dengyang Han, Yi Yuan, Yiyun Cao, Chengmei Shi, Xiangyang Guo, Yang Zhou and Zhengqian Li

    Citation: BMC Anesthesiology 2021 21:186

    Content type: Research

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  11. Hypotension after neuraxial anaesthesia is one of the most common complications during caesarean section. Vasopressors are the most effective method to improve hypotension, but which of these drugs is best for...

    Authors: Tingting Wang, Limei Liao, Xiaohui Tang, Bin Li and Shaoqiang Huang

    Citation: BMC Anesthesiology 2021 21:185

    Content type: Research

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  12. Post-operative pulmonary complications (PPC) can develop in up to 13% of patients undergoing neurosurgical procedures and may adversely affect clinical outcome. The use of intraoperative lung protective ventil...

    Authors: Federico Longhini, Laura Pasin, Claudia Montagnini, Petra Konrad, Andrea Bruni, Eugenio Garofalo, Paolo Murabito, Corrado Pelaia, Valentina Rondi, Fabrizio Dellapiazza, Gianmaria Cammarota, Rosanna Vaschetto, Marcus J. Schultz and Paolo Navalesi

    Citation: BMC Anesthesiology 2021 21:184

    Content type: Research

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  13. Monitored Anesthesia Care (MAC) is an anesthetic service involving the titration of sedatives/analgesics to achieve varying levels of sedation while avoiding general anesthesia (GA) and airway instrumentation....

    Authors: Sang Kim, Brian A. Chang, Amreen Rahman, Hung-Mo Lin, Samuel DeMaria Jr, Jeron Zerillo and David B. Wax

    Citation: BMC Anesthesiology 2021 21:183

    Content type: Research

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  14. Secondary lung injury is the most common non-neurological complication after traumatic brain injury (TBI). Lung-protective ventilation (LPV) has been proven to improve perioperative oxygenation and lung compli...

    Authors: Lulu Jiang, Yujuan Wu, Yang Zhang, Dahao Lu, Keshi Yan and Ju Gao

    Citation: BMC Anesthesiology 2021 21:182

    Content type: Research

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  15. During laparoscopic gynecological surgery, increased peak airway pressure (PAWP) can cause airway leak upon ventilation with the LMA® ProSeal™. We hypothesized that compared with the use of volume-controlled v...

    Authors: Toshiyuki Nakanishi, Seishi Sakamoto, Manabu Yoshimura and Takashi Toriumi

    Citation: BMC Anesthesiology 2021 21:181

    Content type: Research

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  16. Neuroprotection strategies after cardiac arrest (CA)/cardiopulmonary resuscitation (CPR) remain key areas of basic and clinical research. This study was designed to investigate the neuroprotective effects of d...

    Authors: Guangqian Li, LeiQian, Pan Gu and Dan Fan

    Citation: BMC Anesthesiology 2021 21:180

    Content type: Research Article

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  17. Our objective was to evaluate the impact of multimodal analgesia based enhanced recovery protocol on quality of recovery after laparoscopic gynecological surgery.

    Authors: Zhiyu Geng, Hui Bi, Dai Zhang, Changji Xiao, Han Song, Ye Feng, Xinni Cao and Xueying Li

    Citation: BMC Anesthesiology 2021 21:179

    Content type: Research Article

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  18. Point-of-care lung ultrasound (LU) is an established tool in the first assessment of patients with coronavirus disease (COVID-19). Purpose of this study was to evaluate the value of lung ultrasound in COVID-19...

    Authors: Stephanie-Susanne Stecher, Sofia Anton, Alessia Fraccaroli, Jeremias Götschke, Hans Joachim Stemmler and Michaela Barnikel

    Citation: BMC Anesthesiology 2021 21:178

    Content type: Research Article

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  19. Recent studies indicate that ultrasound can detect changes in tracheal diameter during endotracheal tube (ETT) cuff inflation. We sought to assess the accuracy of ultrasound measurement of tracheal diameter, a...

    Authors: Ran Ye, Feifei Cai, Chengnan Guo, Xiaocheng Zhang, Dan Yan, Chengshui Chen and Bin Chen

    Citation: BMC Anesthesiology 2021 21:177

    Content type: Research Article

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  20. There are many factors affecting the success rate of awake orotracheal intubation via fiberoptic bronchoscope. We performed this study was to investigate the effects of head positions on awake Fiberoptic bronc...

    Authors: Zhuo Liu, Li Zhao, Zhongfeng Ma, Meiqi Liu, Xiaohang Qi, Qianqian Jia, Shujuan Liang and Xiaochun Yang

    Citation: BMC Anesthesiology 2021 21:176

    Content type: Research Article

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  21. Open cardiac surgical patients may experience severe acute poststernotomy pain. The ultrasound-guided Pecto-intercostal Fascial Block (PIFB) can cover anterior branches of intercostal nerves from T2 to T6. The...

    Authors: Yang Zhang, Haixia Gong, Biming Zhan and Shibiao Chen

    Citation: BMC Anesthesiology 2021 21:175

    Content type: Research Article

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  22. The number of caesarean deliveries has been increasing. Although intrathecal morphine (ITM) can relieve pain and is widely applied in caesarean deliveries, it is associated with many side effects. Transversus ...

    Authors: Tao-ran Yang, Xue-mei He, Xue-han Li and Ru-rong Wang

    Citation: BMC Anesthesiology 2021 21:174

    Content type: Research

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  23. Megaloblastic anemia or bone marrow changes could occur after prolonged nitrous oxide inhalation via vitamin B12 inactivation related DNA synthesis impairment. Previous researches have studied hematological chang...

    Authors: Ruoxi Wang, Ling Lan, Li Xu, Bo Zhu and Yuguang Huang

    Citation: BMC Anesthesiology 2021 21:171

    Content type: Research

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  24. Transoral thyroidectomy can be performed using nasal or oral intubation. Recently, we encountered two cases of vocal cord granuloma that were suspected to result from intraoperative compression by the oral end...

    Authors: Tsung-Jung Liang, Nai-Yu Wang, Shiuh-Inn Liu and I-Shu Chen

    Citation: BMC Anesthesiology 2021 21:170

    Content type: Case report

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  25. Continuous peripheral nerve catheters (CPNCs) have been used for postoperative pain relief. A common problem encountered with CPNCs is pericatheter leakage, which can lead to dressing adhesive failure. Frequen...

    Authors: Theerawat Chalacheewa, Vanlapa Arnuntasupakul, Lisa Sangkum, Rungrawan Buachai and Jiravud Chanvitayapongs

    Citation: BMC Anesthesiology 2021 21:169

    Content type: Research Article

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  26. There was no “gold standard” to assess the success or failure of thoracic paravertebral block (TPVB). Measurement of skin temperature with infrared thermography (IT) would be a reliable method to evaluate the ...

    Authors: Shuang Zhang, Yong Liu, Xiaohu Liu, Tianzhu Liu, Pengcheng Li and Wei Mei

    Citation: BMC Anesthesiology 2021 21:168

    Content type: Research

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  27. The Surgical Pleth Index (SPI) is an objective tool that can reflect nociception-antinociception balance and guide the use of intraoperative analgesics. Multimodal analgesia has been neglected in many previous...

    Authors: Jian Guo, Weigang Zhu, Qinye Shi, Fangping Bao and Jianhong Xu

    Citation: BMC Anesthesiology 2021 21:167

    Content type: Research

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  28. No previous study investigated the dexmedetomidine-based opioid-free anesthesia (OFA) protocol in cardiac surgery. The main objective of this study was to evaluate the feasibility and the postoperative opioid-...

    Authors: Clément Aguerreche, Gaspard Cadier, Antoine Beurton, Julien Imbault, Sébastien Leuillet, Alain Remy, Cédrick Zaouter and Alexandre Ouattara

    Citation: BMC Anesthesiology 2021 21:166

    Content type: Research

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  29. Although regional cerebral oxygen saturation (rScO2) monitoring has been widely used in clinical practice, the relationship between hemoglobin (dHB) content and rScO2 is incompletely understood. The aim of this s...

    Authors: Lin Liu, Zhipeng Qiang, Jianmin Zhang, Yi Ren, Xin Zhao, Wenya Fu, Zhong Xin, Zenghua Xu, Fang Wang, Lijing Li, Nan Zou, Xuemei Zhang, Lei Feng and Shuxuan Ma

    Citation: BMC Anesthesiology 2021 21:165

    Content type: Research

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  30. Pulmonary artery catheter insertion is a routine practice in high-risk patients undergoing cardiac surgery. However, pulmonary artery catheter insertion is associated with numerous complications that can be de...

    Authors: Hoon Choi, Joon Pyo Jeon, Jaewon Huh, Youme Kim and Wonjung Hwang

    Citation: BMC Anesthesiology 2021 21:73

    Content type: Case report

    Published on:

  31. An increase in blood flow in the forearm arteries has been reported after brachial plexus block (BPB). However, few studies have quantitatively analysed the blood flow of the forearm arteries after BPB or have...

    Authors: Yang Xu, Derong Cui, Junfeng Zhang, Qian Ding, Jing Dong and Yan Wang

    Citation: BMC Anesthesiology 2021 21:164

    Content type: Research Article

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  32. Fluid warming, recommended for fluid rates of > 500 ml h-1, is an integral part of patient temperature management strategies. Fluid warming devices using an uncoated aluminium containing heating element have been...

    Authors: Thorsten Perl, N. Kunze-Szikszay, A. Bräuer, M. Quintel, T. Roy, K. Kerpen and U. Telgheder

    Citation: BMC Anesthesiology 2021 21:163

    Content type: Research

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  33. Nicolaides-Baraitser syndrome (NCBRS) is a rare disease caused by mutations in the SMRCA2 gene, which affects chromatin remodelling and leads to a wide range of symptoms including microcephaly, distinct facial...

    Authors: Marie Goehring, Suma Choorapoikayil, Kai Zacharowski and Leila Messroghli

    Citation: BMC Anesthesiology 2021 21:162

    Content type: Case report

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  34. Exhaled propofol concentrations correlate with propofol concentrations in adult human blood and the brain tissue of rats, as well as with electroencephalography (EEG) based indices of anesthetic depth. The pha...

    Authors: Sebastian Heiderich, Tara Ghasemi, Nils Dennhardt, Robert Sümpelmann, Vanessa Rigterink, Katja Nickel, Oliver Keil, Dietmar Böthig and Christiane E. Beck

    Citation: BMC Anesthesiology 2021 21:161

    Content type: Research

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  35. Unrelieved postoperative pain afflicts millions each year in low and middle income countries (LMIC). Despite substantial advances in the study of pain, this area remains neglected. Current systematic review wa...

    Authors: Gauhar Afshan, Robyna Irshad Khan, Aliya Ahmed, Ali Sarfraz Siddiqui, Azhar Rehman, Syed Amir Raza, Rozina Kerai and Khawaja Mustafa

    Citation: BMC Anesthesiology 2021 21:160

    Content type: Research Article

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  36. The effect of a combination of a goal-directed fluid protocol and preoperative carbohydrate loading on postoperative complications in elderly patients still remains unknown. Therefore, we designed this trial t...

    Authors: Xia Liu, Peng Zhang, Meng Xue Liu, Jun Li Ma, Xin Chuan Wei and Dan Fan

    Citation: BMC Anesthesiology 2021 21:157

    Content type: Research Article

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  37. Remimazolam besylate is a newer benzodiazepine with characteristics of quick onset of effects, short maintenance and recovery times without accumulation in tissues. This trial was conducted to confirm the effi...

    Authors: Xiaoqiang Zhang, Shuang Li and Jing Liu

    Citation: BMC Anesthesiology 2021 21:156

    Content type: Research

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    The Correction to this article has been published in BMC Anesthesiology 2021 21:173

  38. The surge of critically ill patients due to the coronavirus disease-2019 (COVID-19) overwhelmed critical care capacity in areas of northern Italy. Anesthesia machines have been used as alternatives to traditio...

    Authors: Maurizio Bottiroli, Angelo Calini, Riccardo Pinciroli, Ariel Mueller, Antonio Siragusa, Carlo Anelli, Richard D. Urman, Ala Nozari, Lorenzo Berra, Michele Mondino and Roberto Fumagalli

    Citation: BMC Anesthesiology 2021 21:155

    Content type: Research

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  39. The role of dexmedetomidine in preventing postoperative delirium (POD) after cardiac surgery remains controversial because of several recent trials with negative results. We aimed to perform an updated meta-an...

    Authors: Peng Li, Lu-xi Li, Zhen-zhen Zhao, Jian Xie, Cheng-long Zhu, Xiao-ming Deng and Jia-feng Wang

    Citation: BMC Anesthesiology 2021 21:153

    Content type: Research Article

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  40. Measuring blood pressure in patients with obesity is challenging. The ClearSight™ finger cuff (FC) uses the vascular unloading technique to provide continuous non-invasive blood pressure measurements. We aimed...

    Authors: Victoria Eley, Rebecca Christensen, Louis Guy, Kerstin Wyssusek, Anita Pelecanos, Benjamin Dodd, Michael Stowasser and Andre van Zundert

    Citation: BMC Anesthesiology 2021 21:152

    Content type: Research

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  41. Anesthetic management of an adult with failing Fontan physiology is complicated given inherent anatomical and physiological alterations. Neurosurgical interventions including thromboembolectomy may be particul...

    Authors: Caroline Eden, Hugo Clifford, Arthur Wang, Asif Mohammed and Peter Yim

    Citation: BMC Anesthesiology 2021 21:151

    Content type: Case report

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  42. The obstructive sleep apnea syndrome (OSAS) is characterized by intermittent cerebral hypoxia which can cause cognitive alterations. Likewise, hypoxia induced neurocognitive deficits are detectable after gener...

    Authors: Soeren Wagner, Lorenz Sutter, Fabian Wagenblast, Andreas Walther and Jan-Henrik Schiff

    Citation: BMC Anesthesiology 2021 21:150

    Content type: Research Article

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  43. For successful lighted stylet intubation, bending the lighted stylet with an appropriate angle is a prerequisite. The purpose of this study was to compare three different bend angles of 70, 80, and 90 degrees ...

    Authors: Dongwook Won, Jung-Man Lee, Jiwon Lee, Jin-Young Hwang, Tae Kyong Kim, Jee-Eun Chang, Hyerim Kim, Seoyoung Ma and Seong-Won Min

    Citation: BMC Anesthesiology 2021 21:148

    Content type: Research Article

    Published on:

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