Articles

Focused ultrasound enhances the anesthetic effects of topical lidocaine in rats

High-intensity ultrasound has been used to induce acoustic cavitation in the skin and subsequently enhances skin permeability to deliver hydrophobic topical medications including lidocaine. In contrast, instea...

Authors: Hyun-Chul Kim, Wonhye Lee, Mark Böhlke, Kyungho Yoon and Seung-Schik Yoo

Preoperative carbohydrate loading and intraoperative goal-directed fluid therapy for elderly patients undergoing open gastrointestinal surgery: a prospective randomized controlled trial

The effect of a combination of a goal-directed fluid protocol and preoperative carbohydrate loading on postoperative complications in elderly patients still remains unknown. Therefore, we designed this trial t...

Authors: Xia Liu, Peng Zhang, Meng Xue Liu, Jun Li Ma, Xin Chuan Wei and Dan Fan

Efficacy and safety of remimazolam besylate versus propofol during hysteroscopy: single-centre randomized controlled trial

Remimazolam besylate is a newer benzodiazepine with characteristics of quick onset of effects, short maintenance and recovery times without accumulation in tissues. This trial was conducted to confirm the effi...

Authors: Xiaoqiang Zhang, Shuang Li and Jing Liu

The repurposed use of anesthesia machines to ventilate critically ill patients with coronavirus disease 2019 (COVID-19)

The surge of critically ill patients due to the coronavirus disease-2019 (COVID-19) overwhelmed critical care capacity in areas of northern Italy. Anesthesia machines have been used as alternatives to traditio...

Authors: Maurizio Bottiroli, Angelo Calini, Riccardo Pinciroli, Ariel Mueller, Antonio Siragusa, Carlo Anelli, Richard D. Urman, Ala Nozari, Lorenzo Berra, Michele Mondino and Roberto Fumagalli

Residual paralysis caused by 50 mg rocuronium after reversal with 4 mg/kg sugammadex: a case report

Rocuronium-induced neuromuscular blockade can be quickly and completely reversed by administration of an optimal dose of sugammadex. Sugammadex antagonizes rocuronium-induced neuromuscular blockade by encapsul...

Authors: Kohji Uzawa, Hiroyuki Seki and Tomoko Yorozu

Dexmedetomidine reduces the incidence of postoperative delirium after cardiac surgery: a meta-analysis of randomized controlled trials

The role of dexmedetomidine in preventing postoperative delirium (POD) after cardiac surgery remains controversial because of several recent trials with negative results. We aimed to perform an updated meta-an...

Authors: Peng Li, Lu-xi Li, Zhen-zhen Zhao, Jian Xie, Cheng-long Zhu, Xiao-ming Deng and Jia-feng Wang

ClearSight™ finger cuff versus invasive arterial pressure measurement in patients with body mass index above 45 kg/m²

Measuring blood pressure in patients with obesity is challenging. The ClearSight™ finger cuff (FC) uses the vascular unloading technique to provide continuous non-invasive blood pressure measurements. We aimed...

Authors: Victoria Eley, Rebecca Christensen, Louis Guy, Kerstin Wyssusek, Anita Pelecanos, Benjamin Dodd, Michael Stowasser and Andre van Zundert

Carotid approach to anterior circulation thromboembolectomy in an adult with failing fontan physiology: a case report

Anesthetic management of an adult with failing Fontan physiology is complicated given inherent anatomical and physiological alterations. Neurosurgical interventions including thromboembolectomy may be particul...

Authors: Caroline Eden, Hugo Clifford, Arthur Wang, Asif Mohammed and Peter Yim

Short term cognitive function after sevoflurane anesthesia in patients suspect to obstructive sleep apnea syndrome: an observational study

The obstructive sleep apnea syndrome (OSAS) is characterized by intermittent cerebral hypoxia which can cause cognitive alterations. Likewise, hypoxia induced neurocognitive deficits are detectable after gener...

Authors: Soeren Wagner, Lorenz Sutter, Fabian Wagenblast, Andreas Walther and Jan-Henrik Schiff

Preoperative anxiety and its association with patients’ desire for support - an observational study in adults

Preoperative anxiety is prevalent and has harmful effects on postoperative outcomes. However, to date, it is still unclear (i) to what extent patients perceive preoperative anxiety as emotionally distressful, ...

Authors: Stefan Salzmann, Stephen Rienmüller, Stefan Kampmann, Frank Euteneuer and Dirk Rüsch

A pilot study comparing three bend angles for lighted stylet intubation

For successful lighted stylet intubation, bending the lighted stylet with an appropriate angle is a prerequisite. The purpose of this study was to compare three different bend angles of 70, 80, and 90 degrees ...

Authors: Dongwook Won, Jung-Man Lee, Jiwon Lee, Jin-Young Hwang, Tae Kyong Kim, Jee-Eun Chang, Hyerim Kim, Seoyoung Ma and Seong-Won Min

Immediate intravenous epinephrine versus early intravenous epinephrine for in-hospital cardiopulmonary arrest

Intravenous epinephrine has been a key treatment in cardiopulmonary arrest since the early 1960s. The ideal timing for the first dose of epinephrinee is uncertain. We aimed to investigate the association of im...

Authors: Abdullah Bakhsh, Maha Safhi, Ashwaq Alghamdi, Amjad Alharazi, Bedoor Alshabibi, Rajwa Alobaidi and Maryam Alnashri

Effect of intravenous oxycodone on the physiologic responses to extubation following general anesthesia

Endotracheal intubation and extubation may cause undesirable hemodynamic changes. Intravenous oxycodone has recently been introduced and used for relieving hemodynamic alterations in response to intubation, bu...

Authors: Menglu Jiang, Jiawei Ji, Xin Li and Zhenqing Liu

A case report of individualized ventilation in a COVID-19 patient – new possibilities and caveats to consider with flow-controlled ventilation

Flow-controlled ventilation (FCV) is a novel ventilation method increasingly being used clinically, particularly during the current COVID-19 pandemic. However, the continuous flow pattern in FCV during inspira...

Authors: Patrick Spraider, Gabriel Putzer, Robert Breitkopf, Julia Abram, Simon Mathis, Bernhard Glodny and Judith Martini

Sufentanil EC50 for endotracheal intubation with aerosol inhalation of carbonated lidocaine by ultrasonic atomizer

Nebulized lidocaine reduced stress response for endotracheal intubation. However, the impact of novel lidocaine aerosol inhalation for intubation by ultrasonic atomizer was unclear. Hence, we designed aerosol ...

Authors: Qiaoqiao Xu, Zhiqiang Zhou, Ling Ai, Jieqiong Liu and Xuebi Tian

Rupture of an epidural filter connector during bolus administration of local anesthetic: a case report

Epidural catheters are routinely placed for many surgical procedures and to treat various pain conditions. Known complications arising from epidural catheter equipment malfunction include epidural pump failure...

Authors: Daniel A. Nahrwold, Aaron R. Muncey, Nasrin N. Aldawoodi, Raymond M. Evans and Jamie P. Hoffman

Perioperative adherence to continuous positive airway pressure and its effect on postoperative nocturnal hypoxemia in obstructive sleep apnea patients: a prospective cohort study

Although continuous positive airway pressure (CPAP) is the first line treatment for obstructive sleep apnea (OSA) patients, the perioperative adherence rate is unclear. The objective of this study was to deter...

Authors: Colin Suen, Jean Wong, Kahiye Warsame, Yamini Subramani, Tony Panzarella, Rida Waseem, Dennis Auckley, Rabail Chaudhry, Sazzadul Islam and Frances Chung

Correction to: Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation

Authors: Yaru Huang, Xiaotong Sun, Zhaodong Juan, Rui Zhang, Ruoguo Wang, Shuqi Meng, Jiajia Zhou, Yan Li, Keyou Xu and Keliang Xie

Routine point-of-care ultrasound (POCUS) assessment of gastric antral content in traumatic emergency surgical patients for prevention of aspiration pneumonitis: an observational clinical trial

Polytrauma patients are at a higher risk of delayed gastric emptying. To assess the gastric volume, a reliable diagnostic tool is needed to prevent the occurrence of aspiration pneumonia, which remains a serio...

Authors: Mohamed S. Shorbagy, Amr A. Kasem, Ahmed A. Gamal Eldin and Ramy Mahrose

The effect of dexmedetomidine on intraoperative blood glucose homeostasis: secondary analysis of a randomized controlled trial

To investigate the effect of dexmedetomidine on intraoperative blood glucose hemostasis in elderly patients undergoing non-cardiac major surgery.

Authors: Chun-Jing Li, Bo-Jie Wang, Dong-Liang Mu and Dong-Xin Wang

Can perioperative hemodilution be monitored with non-invasive measurement of blood hemoglobin?

Trends in non-invasive measurements of blood hemoglobin (Hb) may be useful for identifying the need for transfusion in the perioperative period.

Authors: Robert G. Hahn, Patrick Y. Wuethrich and Joachim H. Zdolsek

Comparison of transversus abdominis plane catheters with thoracic epidurals for cost and length of stay in open colorectal surgeries: a cohort study

Thoracic epidural analgesia has long been a common method of postoperative analgesia for major open abdominal surgeries and is frequently used within enhanced recovery after surgery programs. An alternative po...

Authors: David Miller, Peter Andriakos, Justin VanBacker, Erin Macbeth, Igor Galay, Dilip Sidhu, Divya Cherukupalli, Edward Lee, Brian Valerian, A. David Chismark, Jonathan Canete and Farzana Afroze

Comparison of remifentanil concentrations with and without dexmedetomidine for the prevention of emergence cough after nasal surgery: a randomized double-blinded trial

Preventing emergence cough after nasal surgery is critical. Emergence cough can provoke immediate postoperative bleeding, which leads to upper airway obstruction. In the present study, we compared the effect-s...

Authors: Ha Yeon Kim, Hyun Jeong Kwak, Dongchul Lee, Ji Hyea Lee, Sang Kee Min and Jong Yeop Kim

Mild increases in plasma creatinine after intermediate to high-risk abdominal surgery are associated with long-term renal injury

The potential relationship between a mild acute kidney injury (AKI) observed in the immediate postoperative period after major surgery and its effect on long term renal function remains poorly defined. Accordi...

Authors: Alexandre Joosten, Brigitte Ickx, Zakaria Mokthari, Luc Van Obbergh, Valerio Lucidi, Vincent Collange, Salima Naili, Philippe Ichai, Didier Samuel, Antonio Sa Cunha, Brenton Alexander, Matthieu Legrand, Fabio Silvio Taccone, Anatole Harrois, Jacques Duranteau, Jean-Louis Vincent…

Prophylactic temporary abdominal aortic balloon occlusion for patients with pernicious placenta previa: a retrospective study

Pernicious placenta previa (PPP) can increase the risk of perioperative complications. During caesarean section in patients with adherent placenta, intraoperative blood loss, hysterectomy rate and transfusion ...

Authors: Fei Huo, Hansheng Liang and Yi Feng

Labor epidural analgesia versus without labor epidural analgesia for multiparous women: a retrospective case control study

Labor epidural analgesia (LEA) effectively relieves the labor pain, but it is still not available consistently for multiparous women in many institutions because of their obviously shortened labor length.

Authors: Shuzhi Luo, Zhaowen Chen, Xujian Wang, Changyu Zhu and Shili Su

Modified STOP-Bang for predicting perioperative adverse events in the Thai population

Undiagnosed obstructive sleep apnea (OSA) is associated with adverse perioperative outcomes. The STOP-Bang questionnaire is a validated screening tool for OSA. However, its precision may vary among different p...

Authors: Lisa Sangkum, Chama Wathanavaha, Visasiri Tantrakul, Munthana Pothong and Cherdkiat Karnjanarachata

A randomized controlled trial of ultrasound-assisted technique versus conventional puncture method for saphenous venous cannulations in children with congenital heart disease

The study investigated the success rate of the great saphenous venous catheter placement performed by ultrasound-assisted technique compared with the conventional puncture method in infants and toddlers with c...

Authors: Yong Bian, Yanhui Huang, Jie Bai, Jijian Zheng and Yue Huang

Spinal subdural hematoma and subdural anesthesia following combined spinal–epidural anesthesia: a case report

Subdural anesthesia and spinal subdural hematoma are rare complications of combined spinal-epidural anesthesia. We present a patient who developed both after multiple attempts to achieve combined spinal–epidur...

Authors: Yanmei Bi and Junying Zhou

Longitudinal assessment of preoperative dexamethasone administration on cognitive function after cardiac surgery: a 4-year follow‐up of a randomized controlled trial

The pathogenesis of postoperative cognitive decline (POCD) is still poorly understood; however, the inflammatory response to surgical procedures seems likely to be involved. In addition, our recent randomized ...

Authors: Sandro Glumac, Goran Kardum, Lidija Sodic, Cristijan Bulat, Ivan Covic, Mladen Carev and Nenad Karanovic

Analysis of risk factors for unplanned reoperation following primary repair of gastrointestinal disorders in neonates

The aim of our study was to identify the factors associated with unplanned reoperations among neonates who had undergone primary repair of gastrointestinal disorders.

Authors: Yu Cui, Rong Cao, Jia Li and Ling-mei Deng

Effects of comprehensive geriatric care models on postoperative outcomes in geriatric surgical patients: a systematic review and meta-analysis

The elderly population is highly susceptible to develop post-operative complications after major surgeries. It is not clear whether the comprehensive geriatric care models are effective in reducing adverse eve...

Authors: Aparna Saripella, Sara Wasef, Mahesh Nagappa, Sheila Riazi, Marina Englesakis, Jean Wong and Frances Chung

Maxillary sinusitis developed as sequelae of accidental middle turbinectomy that occurred during nasotracheal intubation: a case report

Nasotracheal intubation is a very useful technique for orofacial or dental surgery. However, the technique itself can be more traumatic than that of orotracheal intubation. Complications such as turbinectomy o...

Authors: Joungmin Kim, Taehee Pyeon, Hyun Jung Lee and Hyung Chae Yang

Development and validation of a difficult laryngoscopy prediction model using machine learning of neck circumference and thyromental height

Predicting difficult airway is challengeable in patients with limited airway evaluation. The aim of this study is to develop and validate a model that predicts difficult laryngoscopy by machine learning of nec...

Authors: Jong Ho Kim, Haewon Kim, Ji Su Jang, Sung Mi Hwang, So Young Lim, Jae Jun Lee and Young Suk Kwon

Risk factors for pediatric surgical site infection following neurosurgical procedures for hydrocephalus: a retrospective single-center cohort study

Infection is a major complication following cerebral spinal fluid (CSF) diversion procedures for hydrocephalus. However, pediatric risk factors for surgical site infection (SSI) are currently not well defined....

Authors: Miho Shibamura-Fujiogi, Jennifer Ormsby, Mark Breibart, Benjamin Warf, Gregory P. Priebe, Sulpicio G. Soriano, Thomas J. Sandora and Koichi Yuki

Integrated pulmonary index can predict respiratory compromise in high‐risk patients in the post‐anesthesia care unit: a prospective, observational study

Respiratory compromise (RC) including hypoxia and hypoventilation is likely to be missed in the postoperative period. Integrated pulmonary index (IPI) is a comprehensive respiratory parameter evaluating ventil...

Authors: Yasutoshi Kuroe, Yuko Mihara, Shuji Okahara, Kenzo Ishii, Tomoyuki Kanazawa and Hiroshi Morimatsu

The effect of preoperative aminophylline on the recovery profile after major pelvic-abdominal surgeries: a randomized controlled double-blinded study

This study compared the effects of premedication with different doses of aminophylline on the recovery profile after general anaesthesia.

Authors: Samaa A. Kasim, Mahmoud Hussein Bahr, Mohamed Abdelkader and Doaa Abu Elkassim Rashwan

A rare case of difficult airway management in a Klippel-Feil syndrome pediatric patient with osseous torticollis undergone orthopedic surgery

Orthopedic surgery for cervical torticollis poses potential threat to airway management both in tracheal intubation and extubation. Klippel-Feil syndrome (KFS) is a complex syndrome of osseous and visceral ano...

Authors: Xiaoqing Zhang, Jun Wang, Yajie Liu, Zhengqian Li and Bin Han

Evaluation of early postoperative intravenous opioid rescue as a novel quality measure in patients who receive thoracic epidural analgesia: a retrospective cohort analysis and prospective performance improvement intervention

In this study, we explored the utility of intravenous opioid rescue analgesia in the post anesthesia care unit (PACU-OpResc) as a single marker of thoracic epidural analgesia (TEA) failure and evaluated the re...

Authors: Nadav Levy, Peter Santer, Liana Zucco, Sarah Nabel, Galina Korsunsky and Satya Krishna Ramachandran

Malignant hyperthermia when dantrolene is not readily available

Malignant hyperthermia is a rare but life-threatening pharmacogenetic muscle disorder characterized by abnormal hypermetabolic reactions and commonly triggered in susceptible individuals by volatile anesthetic...

Authors: Xiaodan Gong

Intraoperative transfusion practice in burned children in a university hospital over four years: a retrospective analysis

Patient blood management programs should be applied to the pediatric population, but little is known about the current transfusion practice of pediatric burn injury patients. This retrospective study was perfo...

Authors: Eva Wittenmeier, Astor Katharina, Irene Schmidtmann, Eva-Verena Griemert, Marc Kriege, Tatjana König and Pirlich Nina

Case report and review of literature of a rare congenital disorder: Adams-Oliver syndrome

Adams-Oliver syndrome is characterized by the combination of congenital scalp defects and terminal transverse limb defects. In some instances, cardiovascular malformations and orofacial malformations have been...

Authors: Edwin Suarez, Mia J. Bertoli, Jean Daniel Eloy and Shridevi Pandya Shah

A prediction model using machine-learning algorithm for assessing intrathecal hyperbaric bupivacaine dose during cesarean section

The intrathecal hyperbaric bupivacaine dosage for cesarean section is difficult to predetermine. This study aimed to develop a decision-support model using a machine-learning algorithm for assessing intratheca...

Authors: Chang-na Wei, Li-ying Wang, Xiang-yang Chang and Qing-he Zhou

Development and validation of a 3D printed antiviral ventilator filter - a comparative study

The current coronavirus infectious disease 2019 (COVID-19) pandemic has caused unexpected pressure on medical supplies, interrupting supply chains and increasing prices. The supply of antiviral filters which f...

Authors: Ruth Shaylor, Mathew Francis, Esther Shaylor, Solomon Dadia and Barak Cohen

Effect of preoperative versus postoperative use of transversus abdominis plane block with plain 0.25 % bupivacaine on postoperative opioid use: a retrospective study

Enhanced recovery protocols optimize pain control via multimodal approaches that include transversus abdominis plane (TAP) block. The aim of this study was to evaluate the effect of preoperative vs. postoperat...

Authors: Richard Kalu, Peter Boateng, Lauren Carrier, Jaime Garzon, Amy Tang, Craig Reickert and Amalia Stefanou

Dexmedetomidine decreased the post‐thyroidectomy bleeding by reducing cough and emergence agitation – a randomized, double‐blind, controlled study

Bleeding after thyroidectomy occurs due to violent coughing during emergence. Dexmedetomidine is helpful for the smooth emergence and suppression of cough. The purpose of the present study was to compare the e...

Authors: Sang Hun Kim, Yoo Seok Kim, Seongcheol Kim and Ki Tae Jung

Correction to: Induction techniques that reduce redistribution hypothermia: a prospective, randomized, controlled, single blind effectiveness study

An amendment to this paper has been published and can be accessed via the original article.

Authors: Jonathan V. Roth, Leonard E. Braitman and Lacy H. Hunt

Preoperative X-ray C₂C₆AR is applicable for prediction of difficult laryngoscopy in patients with cervical spondylosis

Airway management is one of the most important techniques in anesthesia practice and inappropriate airway management is related with airway injury, brain hypoxia, and even death. The patients with cervical spo...

Authors: Yang Zhou, Yongzheng Han, Zhengqian Li, Yuqing Zhao, Ning Yang, Taotao Liu, Min Li, Jun Wang, Xiangyang Guo and Mao Xu

Effect of intraoperative blood transfusion on Treg and FOXP3 in patients with digestive tract malignancies and different ABO blood types

Blood transfusion can cause immunosuppression and lead to worse outcomes in patients with digestive tract malignancies; however, the specific mechanism behind this is not completely understood. One theory is t...

Authors: Yajun Liu, Junzhi Sun, Yun Xia, Michael R. Lyaker and Jianshe Yu

Lidocaine coinfusion alleviates vascular pain induced by hypertonic saline infusion: a randomized, placebo-controlled trial

Hypertonic saline solution has been frequently utilized in clinical practice. However, due to the nonphysiological osmolality, hypertonic saline infusion usually induces local vascular pain. We conducted this ...

Authors: Zhiping Song, Shibiao Chen, Yang Zhang, Xiaoyun Shi, Na Zhao and Zhengyu Liao