Perioperative medicine and outcome

Section edited by Laura Pasin

This section considers manuscripts concerning anesthesia in the pre-, intra- and post-operative settings. Studies concerning the outcome of patients when this is related to operative anesthesia will also be considered.

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  1. Research article

    Recovery and prediction of postoperative muscle power – is it still a problem?

    In the postoperative period, immediate recovery of muscular power is essential for patient safety, but this can be affected by anaesthetic drugs, opioids and neuromuscular blocking agents (NMBA). In this cohor...

    Martin Zoremba, Dennis Kornmann, Benjamin Vojnar, Rene Burchard, Thomas Wiesmann, Hinnerk Wulf and Thomas Kratz

    BMC Anesthesiology 2017 17:108

    Published on: 22 August 2017

  2. Research article

    A novel thermal compression device for perioperative warming: a randomized trial for feasibility and efficacy

    Inadvertent perioperative hypothermia (IPH) leads to surgical complications and increases length of stay. IPH rates are high with the current standard of care, forced air warming (FAW). Our hypothesis is that ...

    Peter Luke Santa Maria, Chloe Santa Maria, Andreas Eisenried, Nathalia Velasquez, Brian Thomas Kannard, Abhinav Ramani, David Mark Kahn, Amanda Jane Wheeler and John Gerhard Brock-Utne

    BMC Anesthesiology 2017 17:102

    Published on: 11 August 2017

  3. Research article

    Randomized comparison of sevoflurane versus propofol-remifentanil on the cardioprotective effects in elderly patients with coronary heart disease

    It is skeptical about cardioprotective property of sevoflurane in patients undergoing noncardiac surgery, especially in the elderly patients with coronary heart disease. We hypothesized that long duration of s...

    Yunlong Zhang, Wendong Lin, Sheliang Shen, Hongfa Wang, Xiaona Feng and Jiehao Sun

    BMC Anesthesiology 2017 17:104

    Published on: 11 August 2017

  4. Research article

    Surgical frailty assessment: a missed opportunity

    Preoperative frailty predicts adverse postoperative outcomes. Despite the advantages of incorporating frailty assessment into surgical settings, there is limited research on surgical healthcare professionals’ ...

    Gilgamesh Eamer, Jennifer A. Gibson, Chelsia Gillis, Amy T. Hsu, Marian Krawczyk, Emily MacDonald, Reid Whitlock and Rachel G. Khadaroo

    BMC Anesthesiology 2017 17:99

    Published on: 24 July 2017

  5. Research article

    End-of-life perceptions among physicians in intensive care units managed by anesthesiologists in Germany: a survey about structure, current implementation and deficits

    Structural aspects and current practice about end-of-life (EOL) decisions in German intensive care units (ICUs) managed by anesthesiologists are unknown. A survey among intensive care anesthesiologists has bee...

    Manfred Weiss, Andrej Michalsen, Anke Toenjes, Franz Porzsolt, Thomas Bein, Marc Theisen, Alexander Brinkmann, Heinrich Groesdonk, Christian Putensen, Friedhelm Bach and Dietrich Henzler

    BMC Anesthesiology 2017 17:93

    Published on: 11 July 2017

  6. Research article

    Risk factors for pulmonary complications after hepatic resection: role of intraoperative hemodynamic instability and hepatic ischemia

    Postoperative operative pulmonary complications (PPCs) after hepatic surgery are associated with increased length of hospital stays. Intraoperative blood transfusion, extensive resection and different comorbid...

    Victoria Lepere, Antoine Vanier, Yann Loncar, Louis Lemoine, Jean Christophe Vaillant, Antoine Monsel, Eric Savier, Pierre Coriat and Daniel Eyraud

    BMC Anesthesiology 2017 17:84

    Published on: 20 June 2017

  7. Research article

    Lipid emulsion mitigates impaired pulmonary function induced by limb ischemia/reperfusion in rats through attenuation of local cellular injury and the subsequent systemic inflammatory

    Limb ischemia/reperfusion causes inflammation and elicits oxidative stress that may lead to local tissue damage and remote organ such as lung injury. This study investigates pulmonary function after limb ische...

    Fangfang Xia, Yun Xia, Sisi Chen, Lulu Chen, Weijuan Zhu, Yuanqing Chen, Thomas J. Papadimos, Xuzhong Xu and Le Liu

    BMC Anesthesiology 2017 17:83

    Published on: 19 June 2017

  8. Research article

    Sensitivity to Sevoflurane anesthesia is decreased in mice with a congenital deletion of Guanylyl Cyclase-1 alpha

    Volatile anesthetics increase levels of the neurotransmitter nitric oxide (NO) and the secondary messenger molecule cyclic guanosine monophosphate (cGMP) in the brain. NO activates the enzyme guanylyl cyclase ...

    Yasuko Nagasaka, Martin Wepler, Robrecht Thoonen, Patrick Y. Sips, Kaitlin Allen, Jan A. Graw, Vincent Yao, Sara M. Burns, Stefan Muenster, Peter Brouckaert, Keith Miller, Ken Solt, Emmanuel S. Buys, Fumito Ichinose and Warren M. Zapol

    BMC Anesthesiology 2017 17:76

    Published on: 14 June 2017

  9. Research article

    Dose-dependent effects of intravenous methoxamine infusion during hip-joint replacement surgery on postoperative cognitive dysfunction and blood TNF-α level in elderly patients: a randomized controlled trial

    Postoperative cognitive dysfunction (POCD), common in elderly patients, is thought to be closely associated with intraoperative instability of hemodynamics and excessive excretion of tumor necrosis factor-α (T...

    Shenghui Sun, Defeng Sun, Lin Yang, Jun Han, Ruochuan Liu and Lijie Wang

    BMC Anesthesiology 2017 17:75

    Published on: 9 June 2017

  10. Research article

    A pragmatic multi-center trial of goal-directed fluid management based on pulse pressure variation monitoring during high-risk surgery

    Intraoperative fluid therapy guided by mechanical ventilation-induced pulse-pressure variation (PPV) may improve outcomes after major surgery. We tested this hypothesis in a multi-center study.

    Luiz Marcelo Sá Malbouisson, João Manoel Silva Jr., Maria José Carvalho Carmona, Marcel Rezende Lopes, Murilo Santucci Assunção, Jorge Luís dos Santos Valiatti, Claudia Marques Simões and José Otavio Costa Auler Jr.

    BMC Anesthesiology 2017 17:70

    Published on: 30 May 2017

  11. Research article

    Does an electronic cognitive aid have an effect on the management of severe gynaecological TURP syndrome? A prospective, randomised simulation study

    Lack of familiarity with the content of current guidelines is a major factor associated with non-compliance by clinicians. It is conceivable that cognitive aids with regularly updated medical content can guide...

    Michael St.Pierre, Georg Breuer, Dieter Strembski, Christopher Schmitt and Bjoern Luetcke

    BMC Anesthesiology 2017 17:72

    Published on: 30 May 2017

  12. Research article

    Development and validation of a Score for Preoperative Prediction of Obstructive Sleep Apnea (SPOSA) and its perioperative outcomes

    Postoperative respiratory complications (PRCs) are associated with significant morbidity, mortality, and hospital costs. Obstructive sleep apnea (OSA), often undiagnosed in the surgical population, may be a co...

    Christina H. Shin, Stephanie D. Grabitz, Fanny P. Timm, Noomi Mueller, Khushi Chhangani, Karim Ladha, Scott Devine, Tobias Kurth and Matthias Eikermann

    BMC Anesthesiology 2017 17:71

    Published on: 30 May 2017

  13. Research article

    Combination of gabapentin and ramosetron for the prevention of postoperative nausea and vomiting after gynecologic laparoscopic surgery: a prospective randomized comparative study

    As a drug originally introduced for its anticonvulsant effects, gabapentin has been recently shown to be effective in the treatment of nausea and vomiting in various clinical settings. This study compared the ...

    Kyung Mi Kim, Jin Huh, Soo Kyung Lee, Eun Young Park, Jung Min Lee and Hyo Ju Kim

    BMC Anesthesiology 2017 17:65

    Published on: 19 May 2017

  14. Research article

    Continuous femoral nerve blockade and single-shot sciatic nerve block promotes better analgesia and lower bleeding for total knee arthroplasty compared to intrathecal morphine: a randomized trial

    Knee arthroplasty leads to postoperative pain. This study compares analgesia and postoperative bleeding achieved by intrathecal morphine with a continuous femoral plus single-shot sciatic nerve block.

    Nora Elizabeth Rojas Álvarez, Rosemberg Jairo Gomez Ledesma, Adilson Hamaji, Marcelo Waldir Mian Hamaji and Joaquim Edson Vieira

    BMC Anesthesiology 2017 17:64

    Published on: 12 May 2017

  15. Research article

    Effects of colloid pre-loading on thromboelastography during elective intracranial tumor surgery in pediatric patients: hydroxyethyl starch 130/0.4 versus 5% human albumin

    Volume replacement therapy with colloid is still worth studying in major pediatric surgery with potential risk of bleeding. This study assessed the effects of 6% hydroxyethyl starch (HES) 130/0.4 and 5% Human ...

    Yuanzhi Peng, Jianer Du, Xuan Zhao, Xueyin Shi and Yingwei Wang

    BMC Anesthesiology 2017 17:62

    Published on: 27 April 2017

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