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Perioperative medicine and outcome

Section edited by Laura Pasin

This section considers manuscripts concerning anesthesia in the pre-, intra- and post-operative settings. Studies concerning the outcome of patients when this is related to operative anesthesia will also be considered.

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  1. Content type: Research article

    Intravenous dexmedetomidine is known to attenuate stress response in patients undergoing laparoscopic surgery. We investigated whether the addition of the highly selective alpha-2 adrenergic agonist dexmedetom...

    Authors: Zhaojun Qin, Chunyan Xiang, Hongbo Li, Tingting Liu, Leyun Zhan, Zhengyuan Xia, Min Zhang and Jianping Lai

    Citation: BMC Anesthesiology 2019 19:181

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  2. Content type: Research article

    Delayed gastric emptying and the resultant “full stomach” is the most important risk factor for perioperative pulmonary aspiration. Using point-of-care gastric sonography, we aimed to investigate the prevalenc...

    Authors: Li Zhou, Yi Yang, Lei Yang, Wei Cao, Heng Jing, Yan Xu, Xiaojuan Jiang, Danfeng Xu, Qianhui Xiao, Chunling Jiang and Lulong Bo

    Citation: BMC Anesthesiology 2019 19:179

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  3. Content type: Research article

    Postoperative Nausea and Vomiting (PONV) is a dreadful and uncomfortable experience that significantly detracts patients’ quality of life after surgery. This study aimed to examine the antiemetic effect of a s...

    Authors: Sylvanus Kampo, Alfred Parker Afful, Shiraj Mohammed, Michael Ntim, Alexis D. B. Buunaaim and Thomas Winsum Anabah

    Citation: BMC Anesthesiology 2019 19:177

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  4. Content type: Research article

    Patients with left ventricular (LV) hypertrophy may suffer ischemia-reperfusion injuries at the time of cardiac surgery with impairment in left ventricular function. Using transesophageal echocardiography (TEE...

    Authors: Marc Licker, John Diaper, Tornike Sologashvili and Christoph Ellenberger

    Citation: BMC Anesthesiology 2019 19:175

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  5. Content type: Research article

    Since inadequate heparin anticoagulation and insufficient reversal can result in complications during cardiopulmonary bypass (CPB) surgery, heparin anticoagulation monitoring by point-of-care (POC) activated c...

    Authors: Daniel Dirkmann, Elisabeth Nagy, Martin W. Britten and Jürgen Peters

    Citation: BMC Anesthesiology 2019 19:174

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  6. Content type: Research article

    Acute kidney injury (AKI) is a common complication following non-cardiac surgery with adverse short- and long- term morbidity and mortality. Evidence shows that hypoalbuminemia is associated with increased AKI...

    Authors: Nan Li, Hong Qiao, Jing-Fei Guo, Hong-Yun Yang, Xue-Ying Li, Shuang-Ling Li, Dong-Xin Wang and Li Yang

    Citation: BMC Anesthesiology 2019 19:171

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  7. Content type: Research article

    Nasotracheal intubation can potentially result in microbial contamination from the upper respiratory tract to the lower respiratory tracts. However, an ideal nasotracheal disinfection method is yet to be deter...

    Authors: Aiji Sato-Boku, Keiji Nagano, Yoshiaki Hasegawa, Yuji Kamimura, Yoshiki Sento, MinHye So, Eisuke Kako, Masahiro Okuda, Naoko Tachi, Hidekazu Ito, Yushi Adachi and Kazuya Sobue

    Citation: BMC Anesthesiology 2019 19:168

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  8. Content type: Research article

    Intravenous use of sufentanil can elicit cough. This study aimed to evaluate the inhibitory effect of pre-injection of a mall dose of remifentanil on sufentanil-induced cough during the induction of general an...

    Authors: Wendong Lin, Jiehao Sun and Shuying Fu

    Citation: BMC Anesthesiology 2019 19:164

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  9. Content type: Research article

    Postoperative pulmonary complications (PPCs) represent the most frequent complications after esophagectomy. The aim of this study was to identify modifiable risk factors for PPCs and 90-days mortality related ...

    Authors: Kai B. Kaufmann, Wolfgang Baar, Torben Glatz, Jens Hoeppner, Hartmut Buerkle, Ulrich Goebel and Sebastian Heinrich

    Citation: BMC Anesthesiology 2019 19:162

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  10. Content type: Research article

    General (GA)- and epidural-anesthesia may cause a drop in body-core-temperature (BCTdrop), and hypothermia, which may alter tissue oxygenation (StO2) and microperfusion after cytoreductive surgery for ovarian can...

    Authors: L. Kaufner, P. Niggemann, T. Baum, S. Casu, J. Sehouli, A. Bietenbeck, M. Boschmann, C. D. Spies, A. Henkelmann and C. von Heymann

    Citation: BMC Anesthesiology 2019 19:161

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  11. Content type: Case report

    Myasthenia gravis (MG) is a challenge for anesthesia management. This report shows that the use of rocuronium-sugammadex is not free from flaws and highlights the importance of cholinesterase inhibitors manage...

    Authors: Hermann dos Santos Fernandes, Jorge Luiz Saraiva Ximenes, Daniel Ibanhes Nunes, Hazem Adel Ashmawi and Joaquim Edson Vieira

    Citation: BMC Anesthesiology 2019 19:160

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  12. Content type: Research article

    Hysterectomy is a widely performed surgery and neuraxial anesthesia with intrathecal morphine provides superior quality of recovery. Postoperative nausea and vomiting (PONV) is a frequent problem with intrathe...

    Authors: Guilherme Oliveira Campos, Marcelo de Jesus Martins, Gabriel Nascimento Jesus, Paulo Roberto Rios de Oliveira, Caio Nogueira Lessa, João Carlos Macêdo Fernandes de Oliveira Junior, Lucas Jorge Santana de Castro Alves, Rodrigo Leal Alves and Norma Sueli Pinheiro Módolo

    Citation: BMC Anesthesiology 2019 19:159

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  13. Content type: Research article

    Enhanced recovery after surgery programs (ERAS) using thoracic epidural anesthesia and perioperative patient conditioning with omega-3 fatty acids (n3FA), glucose control (GC) and on-demand fluid therapy, resp...

    Authors: Christopher Uhlig, Thomas Rössel, Axel Denz, Sven Seifert, Thea Koch and Axel Rüdiger Heller

    Citation: BMC Anesthesiology 2019 19:156

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  14. Content type: Case report

    Limb-girdle muscular dystrophies (LGMDs) belong to few neuromuscular disorders mainly involving pelvic and shoulder girdle muscles. Also, cardiac or pulmonary complications, increased rhabdomyolysis risk when ...

    Authors: X. Q. Cao, K. Joypaul, F. Cao, L. L. Gui, J. T. Hu and W. Mei

    Citation: BMC Anesthesiology 2019 19:155

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  15. Content type: Review

    Patients undergoing emergency surgery may present with the acute respiratory distress syndrome (ARDS) or develop this syndrome postoperatively. The incidence of ARDS in the postoperative period is relatively l...

    Authors: Denise Battaglini, Chiara Robba, Patricia Rieken Macêdo Rocco, Marcelo Gama De Abreu, Paolo Pelosi and Lorenzo Ball

    Citation: BMC Anesthesiology 2019 19:153

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  16. Content type: Case report

    Respiratory adverse events are not uncommon in the post-anesthesia care unit (PACU) following general anesthesia. In this regard, hyperventilation leading to apnea and desaturation is a rare entity. Here we ha...

    Authors: Parineeta Thapa, Asish Subedi, Anjali Poudel and Pankaj Baral

    Citation: BMC Anesthesiology 2019 19:152

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  17. Content type: Research article

    Real-time photoacoustic gas monitoring is used for personnel exposure and environmental monitoring, but its accuracy varies when organic solvents such as alcohol contaminate measurements. This is problematic f...

    Authors: Jennifer Herzog-Niescery, Thomas Steffens, Martin Bellgardt, Andreas Breuer-Kaiser, Philipp Gude, Heike Vogelsang, Thomas Peter Weber and Hans-Martin Seipp

    Citation: BMC Anesthesiology 2019 19:148

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  18. Content type: Research article

    Emergence-delirium is the most frequent brain dysfunction in children recovering from general anaesthesia, though the pathophysiological background remains unclear. The presented study analysed an association ...

    Authors: Susanne Koch, Anna-Maria Stegherr, Leopold Rupp, Jochen Kruppa, Christine Prager, Sylvia Kramer, Astrid Fahlenkamp and Claudia Spies

    Citation: BMC Anesthesiology 2019 19:146

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  19. Content type: Research article

    The use of the bispectral index (BIS) is widespread in pediatric anesthesia, but few studies have attempted to perform a detailed evaluation of how BIS varies according to age in children under propofol anesth...

    Authors: Fang Wang, Jianmin Zhang, Jie Yu, Muyang Tian, Xiaohuan Cui and Anshi Wu

    Citation: BMC Anesthesiology 2019 19:145

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  20. Content type: Research article

    Complete avoidance of residual neuromuscular blockade (RNMB) during the postoperative period has not yet been achieved in current anesthesia practice. Evidently, compliance with NMB monitoring is persistently ...

    Authors: Gonzalo Domenech, Matías A. Kampel, María E. García Guzzo, Delfina Sánchez Novas, Sergio A. Terrasa and Gustavo Garcia Fornari

    Citation: BMC Anesthesiology 2019 19:143

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  21. Content type: Research article

    The reliability of pulse pressure variation (PPV) and stroke volume variation (SVV) is controversial under pneumoperitoneum. In addition, the usefulness of these indices is being called into question with the ...

    Authors: Joo-Hyun Jun, Rack Kyung Chung, Hee Jung Baik, Mi Hwa Chung, Joon-Sang Hyeon, Young-Goo Lee and Sung-Ho Park

    Citation: BMC Anesthesiology 2019 19:142

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  22. Content type: Review

    Electrical impedance tomography (EIT) is a non-invasive radiation-free monitoring technique that provides images based on tissue electrical conductivity of the chest. Several investigations applied EIT in the ...

    Authors: Elena Spinelli, Tommaso Mauri, Alberto Fogagnolo, Gaetano Scaramuzzo, Annalisa Rundo, Domenico Luca Grieco, Giacomo Grasselli, Carlo Alberto Volta and Savino Spadaro

    Citation: BMC Anesthesiology 2019 19:140

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    The Correction to this article has been published in BMC Anesthesiology 2019 19:172

  23. Content type: Research article

    Intraoperative hypotension increases 30-day mortality and the risks of myocardial injury and acute renal failure. Patients with inadequate volume reserve before the induction of anesthesia are highly exposed. ...

    Authors: Marcell Szabó, Anna Bozó, Katalin Darvas, Alexandra Horváth and Zsolt Dániel Iványi

    Citation: BMC Anesthesiology 2019 19:139

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  24. Content type: Research article

    No study has been conducted to demonstrate the feasibility of an opioid-free anesthesia (OFA) protocol in cardiac surgery to improve patient care. The aim of the present study was to evaluate the effect of OFA...

    Authors: Pierre-Grégoire Guinot, Alexandra Spitz, Vivien Berthoud, Omar Ellouze, Anis Missaoui, Tiberiu Constandache, Sandrine Grosjean, Mohamed Radhouani, Jean-Baptiste Anciaux, Jean-Philippe Parthiot, Jean-Pierre Merle, Nicolas Nowobilski, Maxime Nguyen and Belaid Bouhemad

    Citation: BMC Anesthesiology 2019 19:136

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  25. Content type: Research article

    Right hepatectomy is a complex procedure that carries inherent risks of perioperative morbidity. To evaluate outcome differences between a low central venous pressure fluid intervention strategy and a goal dir...

    Authors: Laurence Weinberg, Lois Mackley, Alexander Ho, Steven Mcguigan, Damian Ianno, Matthew Yii, Jonathan Banting, Vijayragavan Muralidharan, Chong Oon Tan, Mehrdad Nikfarjam and Chris Christophi

    Citation: BMC Anesthesiology 2019 19:135

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  26. Content type: Research article

    Postoperative pulmonary complications (PPCs) increase morbidity and mortality of surgical patients, duration of hospital stay and costs. Postoperative atelectasis of dorsal lung regions as a common PPC has bee...

    Authors: Maria Bauer, Anne Opitz, Jörg Filser, Hendrik Jansen, Rainer H. Meffert, Christoph T. Germer, Norbert Roewer, Ralf M. Muellenbach and Markus Kredel

    Citation: BMC Anesthesiology 2019 19:132

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  27. Content type: Research article

    The efficacy of tranexamic acid (TXA) to reduce perioperative blood loss and allogeneic blood transfusion in cardiac surgeries has been proved in previous studies, but its adverse effects especially seizure ha...

    Authors: Jingfei Guo, Xurong Gao, Yan Ma, Huran Lv, Wenjun Hu, Shijie Zhang, Hongwen Ji, Guyan Wang and Jia Shi

    Citation: BMC Anesthesiology 2019 19:129

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  28. Content type: Research article

    We previously reported that each 100 mg dL− 1 reduction in blood glucose over the range from ≈90 to > 300 mg dL− 1 decreases the shivering threshold (triggering core temperature) in rabbits by 1 °C. However, the ...

    Authors: Keiichi Wada, Taishi Masamune, Hirofumi Ino, Kenta Ueda, Tadahiko Ishiyama, Daniel I. Sessler and Takashi Matsukawa

    Citation: BMC Anesthesiology 2019 19:126

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  29. Content type: Research article

    Renal dysfunction following intraoperative arterial hypotension is mainly caused by an insufficient renal blood flow. It is associated with higher mortality and morbidity rates. We hypothesised that the intrao...

    Authors: Patrick Schäfer, Astrid Fahlenkamp, Rolf Rossaint, Mark Coburn and Ana Kowark

    Citation: BMC Anesthesiology 2019 19:125

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  30. Content type: Research article

    Pharyngeal packing (PP) is commonly performed to reduce the incidence of perioperative blood ingestion (PBI) in nasal surgery (NS), and thus the incidence and severity of postoperative nausea and vomiting (PON...

    Authors: M. Emrah Temel, Tolga Totoz, Kerem Erkalp, Gulen Safiye Temel and Aysin Selcan

    Citation: BMC Anesthesiology 2019 19:121

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  31. Content type: Research article

    Quick and complete recovery of cognitive function after general anesthesia is desirable, particularly for working-age patients. Desflurane is less likely to have long-term effects than older-generation inhalat...

    Authors: Ayako Tojo, Kazuhiro Uchimoto, Gaku Inagawa and Takahisa Goto

    Citation: BMC Anesthesiology 2019 19:119

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  32. Content type: Research article

    Patients undergoing complex spine surgery present with multilevel spinal involvement, advanced age, and multiple comorbidities. Surgery is associated with significant blood loss and remarkable hemodynamic chan...

    Authors: Feng-Cheng Chang, Jr-Rung Lin and Fu-Chao Liu

    Citation: BMC Anesthesiology 2019 19:117

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  33. Content type: Case report

    Maternal cardiac arrest during cesarean section (CS) is an extremely rare but devastating complication. Preventing emergency events from developing into maternal cardiac arrest is one of the most challenging c...

    Authors: Shouming Chen, Lan Wu and Xiaoqin Jiang

    Citation: BMC Anesthesiology 2019 19:116

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  34. Content type: Research article

    Patient satisfaction is a well-established indicator to evaluate the quality of medical care and there is an increasing support for the use of patient-reported experience measures (PREMs) to evaluate satisfact...

    Authors: Wouter Droog, Sanne E. Hoeks, G. Peter van Aggelen, D-Yin Lin, J. Henk Coert, Robert Jan Stolker and Eilish M. Galvin

    Citation: BMC Anesthesiology 2019 19:115

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  35. Content type: Research article

    Several studies have investigated the effects of dexamethasone on post-operative cognitive dysfunction (POCD) or post-operative delirium (POD); however, their conclusions have been inconsistent. Thus, we condu...

    Authors: Li-Qin Li, Cong Wang, Mei-Dan Fang, Hong-Yu Xu, Hong-Liu Lu and Hou-Zhong Zhang

    Citation: BMC Anesthesiology 2019 19:113

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  36. Content type: Research article

    Sevoflurane is one of the most frequently used inhaled anesthetics for general anesthesia. Previously it has been reported that at clinically used doses of sevoflurane, cerebral vasoreactivity is maintained. H...

    Authors: Marianna Juhász, Levente Molnár, Béla Fülesdi, Tamás Végh, Dénes Páll and Csilla Molnár

    Citation: BMC Anesthesiology 2019 19:109

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  37. Content type: Research article

    Terlipressin, in general, is a vasopressor which acts via V1 receptors. Its infusion elevates mean blood pressure and can reduce bleeding which has a splanchnic origin. The primary outcome was to assess the im...

    Authors: Magdy Mohammed Mahdy, Mostafa Samy Abbas, Emad Zarief Kamel, Mohamed Fathy Mostafa, Ragaa Herdan, Shimaa Abbas Hassan, Ramy Hassan, Ahmed M. Taha, Tameem M. Ibraheem, Bashir A. Fadel, Mohammed Geddawy, Jehan Ahmed Sayed and Osama Ali Ibraheim

    Citation: BMC Anesthesiology 2019 19:106

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  38. Content type: Research article

    The safety and efficiency of intravenous administration of tranexamic acid (TXA) in coronary artery bypass grafting (CABG) remains unconfirmed. Therefore, we conducted a meta-analysis on this topic.

    Authors: Yanting Zhang, Yun Bai, Minmin Chen, Youfa Zhou, Xin Yu, Haiyan Zhou and Gang Chen

    Citation: BMC Anesthesiology 2019 19:104

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  39. Content type: Research article

    Ultrasound guidance might decrease the incidence of local anesthetics systemic toxicity (LAST) for many peripheral nerve blocks compared with nerve stimulator guidance. However, it remains uncertain whether ul...

    Authors: Xu-hao Zhang, Yu-jie Li, Wen-quan He, Chun-yong Yang, Jian-teng Gu, Kai-zhi Lu and Bin Yi

    Citation: BMC Anesthesiology 2019 19:103

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  40. Content type: Research article

    Whether thoracic paravertebral block (PVB) is useful in patients undergoing off-pump coronary artery bypass grafting (OPCABG) remains unknown. This study aimed to investigate the feasibility of bilateral PVB c...

    Authors: Lixin Sun, Qiujie Li, Qiang Wang, Fuguo Ma, Wei Han and Mingshan Wang

    Citation: BMC Anesthesiology 2019 19:101

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  41. Content type: Research article

    Acute kidney injury after cardiac surgery significantly associates with morbidity and mortality. Despite not requiring cardiopulmonary bypass, transcatheter aortic valve replacement patients have an incidence ...

    Authors: Akeel M. Merchant, Javier A. Neyra, Abu Minhajuddin, Lauren E. Wehrmann, Richard A. Mills, Sarah K. Gualano, Dharam J. Kumbhani, Lynn C. Huffman, Michael E. Jessen and Amanda A. Fox

    Citation: BMC Anesthesiology 2019 19:99

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  42. Content type: Research article

    Most centres use fresh frozen plasma (FFP) based protocols to prevent or treat haemostatic disturbances during liver transplantation. In the present study, we used a rotational thrombelastometry (ROTEM™, TEM, ...

    Authors: Matthias Hartmann, Caroline Walde, Daniel Dirkmann and Fuat H. Saner

    Citation: BMC Anesthesiology 2019 19:97

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  43. Content type: Research article

    Insertion of a flexible laryngeal mask airway (LMA Flexible) is known to be more difficult than that of a conventional laryngeal mask airway. The 90° rotation technique can improve the success rate with a conv...

    Authors: Bon-Wook Koo, Ah-Young Oh, Jung-Won Hwang, Hyo-Seok Na and Seong-Won Min

    Citation: BMC Anesthesiology 2019 19:95

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  44. Content type: Research article

    Increased lung water and the resultant atelectasis are significant pulmonary complications after cardiopulmonary bypass (CPB) in children undergoing cardiac surgery; these complications are observed after CPB ...

    Authors: Mohamed Elayashy, Mai A. Madkour, Ahmed Abdelaal Ahmed Mahmoud, Hisham Hosny, Amr Hussein, Ahmed Nabih, Ahmed Lofty, Hamza Mohamed Hamza, Passaint Hassan, Mohamed Wagih and Ahmed Kareem Mohamed

    Citation: BMC Anesthesiology 2019 19:93

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  45. Content type: Research article

    Hemostasis is the dynamic equilibrium between coagulation and fibrinolysis. During pregnancy, the balance shifts toward a hypercoagulative state; however placental abruption and abnormal placentations may lead...

    Authors: Alessandra Spasiano, Carola Matellon, Daniele Orso, Alessandro Brussa, Maria Cafagna, Anna Marangone, Teresa Dogareschi, Tiziana Bove, Roberta Giacomello, Desrè Fontana, Luigi Vetrugno and Giorgio Della Rocca

    Citation: BMC Anesthesiology 2019 19:90

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  46. Content type: Research article

    Although serum creatinine concentration has been traditionally used as an index of renal function in clinical practice, it is considered relatively inaccurate, especially in patients with mild renal dysfunctio...

    Authors: Myung-Soo Jang, Jae-Sik Nam, Jun-Young Jo, Chang-Hwa Kang, Seung Ah. Ryu, Eun-Ho Lee and In-Cheol Choi

    Citation: BMC Anesthesiology 2019 19:88

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  47. Content type: Research article

    Patient monitoring is critical for perioperative patient safety as anesthesiologists routinely make crucial therapeutic decisions from the information displayed on patient monitors. Previous research has shown...

    Authors: David W. Tscholl, Lucas Handschin, Julian Rössler, Mona Weiss, Donat R. Spahn and Christoph B. Nöthiger

    Citation: BMC Anesthesiology 2019 19:87

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