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Pain management and analgesia

Section edited by Patrice Forget

This section considers manuscripts relating to the management of pain in all settings.

Page 1 of 2

  1. Content type: Research article

    Continuous epidural infusion (CEI) has some disadvantages, such as increased local anesthetic consumption and limited area of anesthetic distribution. Programmed intermittent bolus (PIB) is a technique of epid...

    Authors: M. Higashi, K. Shigematsu, E. Nakamori, S. Sakurai and K. Yamaura

    Citation: BMC Anesthesiology 2019 19:107

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  3. Content type: Research article

    It is still unknown whether newborn infant parasympathetic evaluation (NIPE), based on heart rate variability (HRV) as a reflection of parasympathetic nerve tone, can predict the hemodynamic response to a noci...

    Authors: Kan Zhang, Siyuan Wang, Lei Wu, Yun’an Song, Meihua Cai, Mazhong Zhang and Jijian Zheng

    Citation: BMC Anesthesiology 2019 19:98

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  4. Content type: Research article

    Postoperative visceral pain is common after surgery and previous studies have demonstrated that oxycodone is an effective treatment. In this study, we compared the effects of preemptive oxycodone to equal dose...

    Authors: Yi An, Lei Zhao, Tianlong Wang, Jiapeng Huang, Wei Xiao, Ping Wang, Lixia Li, Zhongjia Li and Xiaoxu Chen

    Citation: BMC Anesthesiology 2019 19:96

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  5. Content type: Research article

    The ultrasound-guided proximal intercostal block (PICB) is performed at the proximal intercostal space (ICS) between the internal intercostal membrane (IIM) and the endothoracic fascia/parietal pleura (EFPP) c...

    Authors: Nantthasorn Zinboonyahgoon, Panya Luksanapruksa, Sitha Piyaselakul, Pawinee Pangthipampai, Suphalerk Lohasammakul, Choopong Luansritisakul, Sunsanee Mali-ong, Nawaporn Sateantantikul, Theera Chueaboonchai and Kamen Vlassakov

    Citation: BMC Anesthesiology 2019 19:94

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  6. Content type: Research article

    The purpose of this study was to compare the effects of scalp nerve block (SNB) and local anesthetic infiltration (LA) with 0.75% ropivacaine on postoperative inflammatory response, intraoperative hemodynamic ...

    Authors: Xi Yang, Jing Ma, Ke Li, Lei Chen, Rui Dong, Yayuan Lu, Zongze Zhang and Mian Peng

    Citation: BMC Anesthesiology 2019 19:91

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  7. Content type: Research article

    Previous studies have demonstrated that dexmedetomidine improves the quality of postoperative analgesia. In the present study, we performed a meta-analysis of randomized controlled trials to quantify the effec...

    Authors: Miaomiao Feng, Xuhui Chen, Tongtong Liu, Chuanhan Zhang, Li Wan and Wenlong Yao

    Citation: BMC Anesthesiology 2019 19:81

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  8. Content type: Research article

    Buprenorphine, a partial opioid agonist, displaces full opioid agonists from receptors and may impede surgical pain management. We report the effects of a sublingual formulation of buprenorphine-naloxone, Subo...

    Authors: Yvette N. Martin, Atousa Deljou, Toby N. Weingarten, Darrell R. Schroeder and Juraj Sprung

    Citation: BMC Anesthesiology 2019 19:68

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  9. Content type: Research article

    Mismanagement of remifentanil leads to severe side effects such as opioid-induced tolerance and hyperalgesia. Recently studies revealed an alternative withdrawal method to limit these side effects. A gradual w...

    Authors: Sarah Saxena, Kimberly Gonsette, Willy Terram, Isabelle Huybrechts, Daniel A. Nahrwold, Matteo Cappello, Luc Barvais and Edgard Engelman

    Citation: BMC Anesthesiology 2019 19:60

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  11. Content type: Research article

    Breast cancer surgery is one of the most common surgeries among the female population. Nearly half of the patients suffer chronic pain following breast cancer surgery, and 24% of them categorizing their pain a...

    Authors: Başak Altıparmak, Melike Korkmaz Toker, Ali İhsan Uysal and Semra Gümüş Demirbilek

    Citation: BMC Anesthesiology 2019 19:31

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  12. Content type: Research article

    This preclinical study in humans was designed to selectively induce delayed nociceptive pain responses to individually titrated laser stimulation, enabling separate bedside intensity scoring of both immediate ...

    Authors: Anna Sellgren Engskov, Agneta Troilius Rubin and Jonas Åkeson

    Citation: BMC Anesthesiology 2019 19:29

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  13. Content type: Research article

    Standardizing concentrations of intravenous infusions enables pre-preparation and is effective in improving patient safety by avoiding large deviations from the prescribed concentration that can occur when inf...

    Authors: Asia N Rashed, Cate Whittlesea, Caroline Davies, Ben Forbes and Stephen Tomlin

    Citation: BMC Anesthesiology 2019 19:26

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  14. Content type: Research article

    Quadratus lumborum (QL) block is increasingly being used as a new abdominal nerve block technique. In some studies of mid and lower abdominal and hip analgesia, continuous QL block achieved favorable outcomes ...

    Authors: Qiang Zhu, Li Li, Zhaoyun Yang, Jinmei Shen, Rong Zhu, Yu Wen, Wenwu Cai and Lei Liu

    Citation: BMC Anesthesiology 2019 19:23

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  15. Content type: Research article

    Although pain treatment is an important objective in prehospital emergency medicine the incidence of oligoanalgesia is still high in prehospital patients. Given that prehospital emergency medicine in Germany i...

    Authors: Stefan J. Schaller, Felix P. Kappler, Claudia Hofberger, Jens Sattler, Richard Wagner, Gerhard Schneider, Manfred Blobner and Karl-Georg Kanz

    Citation: BMC Anesthesiology 2019 19:18

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  16. Content type: Research article

    It has been reported that postoperative cognitive dysfunction (POCD) is correlated with the degeneration of the central nervous system, oxidative stress, inflammation, and endocrine and immune dysfunction. Inc...

    Authors: Yuan Zhang, Hong-Guang Bao, Yun-Luo Lv, Yan-Na Si, Liu Han, Hong-Yu Wang, Yu-Jie Gao, Wei-Qing Jiang and Chen Zhang

    Citation: BMC Anesthesiology 2019 19:6

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  17. Content type: Case report

    This report describes one case of paravertebral haemorrhage after ultrasound-guided thoracic paravertebral block (TPVB) that may have been attributed to the inadvertent puncture of the posterior intercostal ar...

    Authors: Linlin Song, Yin Zhou and Da Huang

    Citation: BMC Anesthesiology 2018 18:196

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  18. Content type: Research article

    To compare the analgesic effects of patient-controlled intravenous analgesia (PCA) with hydromorphone and sufentanil after thoracic surgery on postoperative pulmonary complications (PPCs).

    Authors: Guangming Yan, Jie Chen, Guiying Yang, Guangyou Duan, Zhiyong Du, Zubin Yu, Jing Peng, Wei Liao and Hong Li

    Citation: BMC Anesthesiology 2018 18:192

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  19. Content type: Research article

    Multiorifice catheters have been shown to provide superior analgesia and significantly reduce local anesthetic consumption compared with end-hole catheters in epidural studies. This prospective, blinded, rando...

    Authors: Alessandra Novello-Siegenthaler, Mehdi Hamdani, Irène Iselin-Chaves and Roxane Fournier

    Citation: BMC Anesthesiology 2018 18:191

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  20. Content type: Research article

    Surgery for aortic coarctation requires special care during anesthesia due to severe pain during the lateral thoracotomy incision, intraoperative hemodynamic instability and the need for large doses of intra- ...

    Authors: Amany H. Saleh, Passaint F. Hassan, Mohamed Elayashy, Hamza M. Hamza, Mona H. Abdelhamid, Mai A. Madkour, Pierre Z. Tawadros, Heba Omar, Mohamed M. Kamel, Marwa Zayed and Mohamed Helmy

    Citation: BMC Anesthesiology 2018 18:178

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  21. Content type: Research article

    Epidural catheter re-siting in parturients receiving labour epidural analgesia is distressing to the parturient and places them at increased complications from a repeat procedure. The aim of this study was to ...

    Authors: John Song En Lee, Rehena Sultana, Nian Lin Reena Han, Alex Tiong Heng Sia and Ban Leong Sng

    Citation: BMC Anesthesiology 2018 18:176

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  22. Content type: Research article

    In-wound catheters for infusion of local anaesthetic for post-caesarean section analgesia are well tolerated in parturients. Few studies have examined continuous in-wound infusion of a combination of local ana...

    Authors: Jozica Wagner-Kovacec, Petra Povalej-Brzan and Dusan Mekis

    Citation: BMC Anesthesiology 2018 18:165

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  23. Content type: Research article

    The purpose of this study was to investigate the feasibility, accuracy and efficiency of the facet joint injections in the lumbar spine by ultrasound guided versus lose dose computed tomography (CT) guidance.

    Authors: Ling Ye, Chuanbing Wen and Hui Liu

    Citation: BMC Anesthesiology 2018 18:160

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  24. Content type: Research article

    Continuous epidural infusion (CEI) is the standard application setting for epidural infusion. A new mode, the programmed intermittent epidural bolus (PIEB) technique, showed reduced local anesthetic (LA) consu...

    Authors: Thomas Wiesmann, Lilli Hoff, Lara Prien, Alexander Torossian, Leopold Eberhart, Hinnerk Wulf and Carsten Feldmann

    Citation: BMC Anesthesiology 2018 18:154

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  25. Content type: Research article

    We performed a randomized, blinded pilot study in 12 volunteers to assess the feasibility to reposition an intentionally displaced suture-method catheter for two different insertion techniques for adductor can...

    Authors: Zarah Maria Jordahn, Tobias Stenbjerg Lyngeraa, Ulrik Grevstad, Christian Rothe, Lars Hyldborg Lundstrøm and Kai Henrik Wiborg Lange

    Citation: BMC Anesthesiology 2018 18:150

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  26. Content type: Research article

    Postoperative pain is one of the most common symptoms after surgery, which brings physical discomfort to patients. In addition, it may cause a series of complications, and even affect the long-term quality of ...

    Authors: Fuxi Song, Chunmiao Ye, Feng Qi, Ping Zhang, Xuexiang Wang, Yanfeng Lü, Alejandro Fernandez-Escobar, Chao Zheng and Liang Li

    Citation: BMC Anesthesiology 2018 18:145

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    The Retraction Note to this article has been published in BMC Anesthesiology 2019 19:20

  27. Content type: Research article

    Proximal brachial plexus blocks can lead to an extended period of motor paralysis and delay the return of motor function. This could influence patient satisfaction, and extend hospitalizations. The aim of the ...

    Authors: Weijuan Zhu, Riyong Zhou, Lulu Chen, Yuanqing Chen, Lvdan Huang, Yun Xia, Thomas J. Papadimos and Xuzhong Xu

    Citation: BMC Anesthesiology 2018 18:143

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  28. Content type: Research article

    Morphine and oxycodone are considered as wide-spreadly used opioids for moderate/severe cancer pain. However, debate exists about the evidence regarding their relative tolerability and underlying results.

    Authors: Kai-Kai Guo, Cheng-Qi Deng, Gui-Jun Lu and Guo-Li Zhao

    Citation: BMC Anesthesiology 2018 18:132

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    The Correction to this article has been published in BMC Anesthesiology 2018 18:173

  29. Content type: Research article

    Patients undergoing craniotomy operations are prone to various noxious stimuli, many strategies are commenced to provide state of analgesia, for better control of the stress response and to overcome its undesi...

    Authors: Ahmed Abdalla Mohamed, Tarek Ahmed Radwan, Mohamed Mahmoud Mohamed, Hatem Abdellatif Mohamed, Mohamed Farid Mohamed Elemady, Safinaz Hassan Osman, Tamer Fayez Safan, Tamer Mohamed Khair, Norhan Abdelaleem Ali, Rania Samir Fahmy, Mohamed Ibrahim Belita, Shady Rady Abdalla, Ahmed Abdelaziz Seleem, Ehab Mohi Atta, Osama Ismail Zaid, Ahmed Shaker Ragab…

    Citation: BMC Anesthesiology 2018 18:129

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  30. Content type: Research article

    Neurodegeneration is associated with changes in basal cellular function due to the dysregulation of autophagy. A recent study introduced the involvement of autophagy during spinal nerve ligation (SNL). Nefopam...

    Authors: Seon-Hee Oh, Myung Ha Yoon, Kyung Joon Lim, Byung Sik Yu, In Gook Jee and Ki Tae Jung

    Citation: BMC Anesthesiology 2018 18:97

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  31. Content type: Research article

    Due to its potential beneficial effects, intra- and postoperative application of intravenous lidocaine has become increasingly accepted over the last couple of years, e.g. in patients undergoing laparoscopic s...

    Authors: Christian P. Both, Jörg Thomas, Philipp K. Bühler, Achim Schmitz, Markus Weiss and Tobias Piegeler

    Citation: BMC Anesthesiology 2018 18:88

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  32. Content type: Research article

    Interleukin 2 (IL-2) influences the development and severity of pain due to its antinociceptive and immunomodulatory effects. Its production is influenced by the increased expression of c-Cbl (Casitas B-lineag...

    Authors: Ji Seon Jeong, Ha Yeon Kim, Byung Seop Shin, Ae Ryoung Lee, Ji Hyun Yoon, Tae Soo Hahm and Ja Eun Lee

    Citation: BMC Anesthesiology 2018 18:87

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  33. Content type: Research article

    The main objective of this review is to perform a systematic review and meta-analysis of the existing evidence related to the analgesic efficacy with the use of conventional, upper arm intravenous regional ane...

    Authors: Valerie Dekoninck, Yasmine Hoydonckx, Marc Van de Velde, Jean-Paul Ory, Jasperina Dubois, Luc Jamaer, Hassanin Jalil and Björn Stessel

    Citation: BMC Anesthesiology 2018 18:86

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  34. Content type: Research article

    Current pain assessment and treatment does not address every patient’s requirements. Although the Polish national guidelines for post-operative pain management have been published, many patients experience sev...

    Authors: Michał Borys, Klaudia Zyzak, Agata Hanych, Michał Domagała, Piotr Gałkin, Katarzyna Gałaszkiewicz, Agata Kłaput, Kai Wróblewski, Justyna Miękina, Dariusz Onichimowski and Mirosław Czuczwar

    Citation: BMC Anesthesiology 2018 18:83

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  35. Content type: Research article

    Studies have shown that dexmedetomidine (Dex) can prolong the duration of analgesia when added to local anaesthetic as an adjuvant in a central or peripheral nerve block. We hypothesized that intrathecal Dex c...

    Authors: Feng Xia, Xiangyang Chang, Yinfa Zhang, Lizhong Wang and Fei Xiao

    Citation: BMC Anesthesiology 2018 18:74

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  36. Content type: Research article

    Spinal block is a common procedure for lower limbs surgery. Fentanyl, a synthetic opioid and dexmedetomidine, a selective α2 agonist have been used as adjuvants in spinal anesthesia to prolong intraoperative a...

    Authors: Poupak Rahimzadeh, Seyed Hamid Reza Faiz, Farnad Imani, Pooya Derakhshan and Saeed Amniati

    Citation: BMC Anesthesiology 2018 18:62

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  37. Content type: Research article

    While opioids are the mainstay for post-operative analgesia after lower segment caesarean section, they are associated with various untoward effects. Ultrasound guided transversus abdominis plane (TAP) block h...

    Authors: Ashok Jadon, Priyanka Jain, Swastika Chakraborty, Mayur Motaka, Sudhansu Sekhar Parida, Neelam Sinha, Amit Agrawal and Asit Kumar Pati

    Citation: BMC Anesthesiology 2018 18:53

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  38. Content type: Research article

    Enhanced Recovery After Surgery (ERAS) pathways have been shown in multiple surgical disciplines to improve outcomes, including reduced opioid consumption, length of stay, and post-operative nausea and vomitin...

    Authors: Catherine Chiu, Pedram Aleshi, Laura J. Esserman, Christina Inglis-Arkell, Edward Yap, Elizabeth L. Whitlock and Monica W. Harbell

    Citation: BMC Anesthesiology 2018 18:41

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  39. Content type: Research article

    Radical surgery for colorectal cancer, associated with moderate to severe postoperative pain, needs multimodal analgesia with opioid for analgesia. Despite considerable advancements, the psychological implicat...

    Authors: Yanqing Yang, Jianping Wu, Huiling Li, Sujuan Ye, Xiaoying Xu, Ling Cheng, Lina Zhu, Zhiyou Peng and Zhiying Feng

    Citation: BMC Anesthesiology 2018 18:37

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  41. Content type: Research article

    The primary goal of this study was to determine whether administration of intrathecal morphine reduces postoperative pain. The secondary goal was to determine the effect of intrathecal morphine upon circulatin...

    Authors: Martin Kaczocha, Syed Azim, James Nicholson, Mario J. Rebecchi, Yong Lu, Tian Feng, Jamie L. Romeiser, Ruth Reinsel, Sabeen Rizwan, Shivam Shodhan, Nora D. Volkow and Helene Benveniste

    Citation: BMC Anesthesiology 2018 18:27

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  42. Content type: Research article

    Percutaneous nephrolithotomy (PCNL) is a minimally invasive surgical procedure for renal calculi, and nephrostomy tubes lead to postoperative pain after PCNL. Regional techniques (e.g., epidural analgesia and ...

    Authors: Zehra Hatipoglu, Ersel Gulec, Mediha Turktan, Volkan Izol, Atilla Arıdogan, Yasemin Gunes and Dilek Ozcengiz

    Citation: BMC Anesthesiology 2018 18:24

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  44. Content type: Research article

    Although the safety and effectiveness of the short-axis in-plane method has been confirmed for lumbar plexus block, the operation is difficult and has a high rate of epidural spread at the plane of the articul...

    Authors: Rui Lu, Chengcheng Shen, Chunyong Yang, Yan Chen, Juanjuan Li and Kaizhi Lu

    Citation: BMC Anesthesiology 2018 18:17

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  45. Content type: Research article

    Optimal patient positioning is perceived as an essential factor to increase the success of performing neuraxial blockade. The primary objective of this study was to evaluate the benefit of using a visual image...

    Authors: Usha Gurunathan, Shakeel Meeran Kunju, Karen Elizabeth Hay and Sharyn van Alphen

    Citation: BMC Anesthesiology 2018 18:11

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  46. Content type: Research article

    This pilot study was designed to compare the efficacy of ultramicronized palmitoylethanolamide (um-PEA) as add-on therapy to tapentadol (TP) with TP therapy only in patients suffering from chronic low back pai...

    Authors: Maria Beatrice Passavanti, Marco Fiore, Pasquale Sansone, Caterina Aurilio, Vincenzo Pota, Manlio Barbarisi, Daniela Fierro and Maria Caterina Pace

    Citation: BMC Anesthesiology 2017 17:171

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  47. Content type: Research article

    Duloxetine, Etoricoxib and opioid are of the commonly administered drugs in Lumbar laminectomy. The aim of this study is to assess the effect of perioperative use of Duloxetine in combination with Etoricoxib o...

    Authors: Josef Zekry Attia and Haidy Salah Mansour

    Citation: BMC Anesthesiology 2017 17:162

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  48. Content type: Research article

    Persistent post-surgical pain is a difficult clinical problem. In this study, we intend to explore the mechanism underlying the persistent post-surgical pain in SMIR (skin/muscle incision and retraction) rats.

    Authors: Zhisong Li, Yaru Li, Jing Cao, Xuemin Han, Weihua Cai, Weidong Zang, Jitian Xu and Wei Zhang

    Citation: BMC Anesthesiology 2017 17:150

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  50. Content type: Research article

    Dexmedetomidine is a highly selective adrenergic receptor agonist, which has a dose-dependent sedative hypnotic effect. Furthermore, it also has pharmacological properties, and the ability to inhibit sympathet...

    Authors: Wan-Wei Jiang, Qing-Hui Wang, Ya-Jing Liao, Pai Peng, Min Xu and Li-Xin Yin

    Citation: BMC Anesthesiology 2017 17:130

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