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Critical care

Section edited by Todd Sarge

This section deals with all manuscripts related to critical care and ICU medicine.

Page 1 of 4

  1. Content type: Research article

    Hypophosphatemia generally occurs in Intensive Care Units (ICUs), but its impact is often ignored. The aim of this study was to investigate whether hypophosphatemia can be a risk factor for ICU 28-day mortality.

    Authors: Lichun Wang, Chaoxing Xiao, Lei Chen, Xiaofei Zhang and Qiuye Kou

    Citation: BMC Anesthesiology 2019 19:86

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  2. Content type: Case report

    In patients with paroxysmal nocturnal hemoglobinuria (PNH), the membrane-attack complex (MAC) formed on red blood cells (RBCs) causes hemolysis due to the patient’s own activated complement system by an infect...

    Authors: Yuko Kawamoto, Tasuku Nishihara, Aisa Watanabe, Kazuo Nakanishi, Taisuke Hamada, Amane Konishi, Naoki Abe, Sakiko Kitamura, Keizo Ikemune, Yuichiro Toda and Toshihiro Yorozuya

    Citation: BMC Anesthesiology 2019 19:83

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  3. Content type: Research article

    This study investigated the associations of fluctuations in serum chloride (Cl−) levels with 30-day mortality after intensive care unit (ICU) admission among critically ill patients.

    Authors: Hyo Jin Kim, Tak Kyu Oh, In-Ae Song and Jae Ho Lee

    Citation: BMC Anesthesiology 2019 19:79

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  4. Content type: Research article

    Extracorporeal membrane oxygenation (ECMO) is often used in critical patients with severe myocardial failure. However, the mortality rate of patients on ECMO is often high. Recent studies have suggested that e...

    Authors: Tsung-Yu Tsai, Kun-Hua Tu, Feng-Chun Tsai, Yu-Yun Nan, Pei-Chun Fan, Chih-Hsiang Chang, Ya-Chung Tian, Ji-Tseng Fang, Chih-Wei Yang and Yung-Chang Chen

    Citation: BMC Anesthesiology 2019 19:73

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  5. Content type: Research article

    Acute kidney injury (AKI) is strongly associated with high morbidity and mortality of critically ill patients. In the last years several different biological markers with higher sensitivity and specificity for...

    Authors: Laura Pasin, Sabrina Boraso and Ivo Tiberio

    Citation: BMC Anesthesiology 2019 19:62

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  6. Content type: Research article

    Sepsis and other infectious complications are major causes of mortality and morbidity in patients after cardiac surgery. Whereas conventional blood culture (BC) suffers from low sensitivity as well as a report...

    Authors: Kevin Pilarczyk, Peter-Michael Rath, Joerg Steinmann, Matthias Thielmann, Stephan A. Padosch, Max Dürbeck, Heinz Jakob and Fabian Dusse

    Citation: BMC Anesthesiology 2019 19:59

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  7. Content type: Research article

    A common postoperative complication found among patients who are critically ill is delirium, which has a high mortality rate. A predictive model is needed to identify high-risk patients in order to apply strat...

    Authors: Onuma Chaiwat, Mellada Chanidnuan, Worapat Pancharoen, Kittiya Vijitmala, Praniti Danpornprasert, Puriwat Toadithep and Chayanan Thanakiattiwibun

    Citation: BMC Anesthesiology 2019 19:39

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    The Correction to this article has been published in BMC Anesthesiology 2019 19:58

  8. Content type: Research article

    Extra Corporeal Membrane Oxygenation (ECMO) has become an accepted treatment option for severely ill patients. Due to a limited availability of ECMO support therapy, patients must often be transported to a spe...

    Authors: Stefan Felix Ehrentraut, Barbara Schroll, Stefan Lenkeit, Heidi Ehrentraut, Christian Bode, Stefan Kreyer, Florian Kögl, Felix Lehmann, Thomas Muders, Martin Scholz, Claudia Strater, Folkert Steinhagen, Nils Ulrich Theuerkauf, Carsten Weißbrich, Christian Putensen and Jens-Christian Schewe

    Citation: BMC Anesthesiology 2019 19:19

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  9. Content type: Research article

    Hemorrhage and blood loss are still among the main causes of preventable death. Global hemostatic assays are useful point-of-care test (POCT) devices to rapidly detect cumulative effects of plasma factors and ...

    Authors: H.-G. Topf, E. R. Strasser, G. Breuer, W. Rascher, M. Rauh and F. B. Fahlbusch

    Citation: BMC Anesthesiology 2019 19:10

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  10. Content type: Research article

    This study aimed at developing and validating a scoring model to stratify critically ill patients after cardiac surgery based on risk for dysphagia, a common but often neglected complication.

    Authors: Xiao-Dong Zhou, Wei-Hua Dong, Chu-Huan Zhao, Xia-Fei Feng, Wei-Wei Wen, Wen-Yi Tu, Meng-Xing Cai, Tian-Cheng Xu and Qiang-Li Xie

    Citation: BMC Anesthesiology 2019 19:7

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  11. Content type: Research article

    Muscle wasting in critically ill patients is associated with negative clinical outcomes. Ultrasound quadriceps femoris muscle assessment may constitute a convenient tool to evaluate muscle wasting. Nevertheless, ...

    Authors: Emmanuel Pardo, Hanen El Behi, Priscilla Boizeau, Franck Verdonk, Corinne Alberti and Thomas Lescot

    Citation: BMC Anesthesiology 2018 18:205

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  12. Content type: Review

    Fluids are by far the most commonly administered intravenous treatment in patient care. During critical illness, fluids are widely administered to maintain or increase cardiac output, thereby relieving overt t...

    Authors: Claude Martin, Andrea Cortegiani, Cesare Gregoretti, Ignacio Martin-Loeches, Carole Ichai, Marc Leone, Gernot Marx and Sharon Einav

    Citation: BMC Anesthesiology 2018 18:200

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  13. Content type: Technical advance

    Perioperative bleeding and transfusion are important causes of morbidity and mortality in patients undergoing liver transplantation. The aim of this study is to assess whether viscoelastic tests-guided therapy...

    Authors: Raffael P. C. Zamper, Thiago C. Amorim, Veronica N. F. Queiroz, Jordana D. O. Lira, Luiz Guilherme V. Costa, Flavio Takaoka, Nicole P. Juffermans and Ary S. Neto

    Citation: BMC Anesthesiology 2018 18:198

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  14. Content type: Research article

    An anesthesiologists’ work presents with numerous occupational risks owing to the large amount of time spent inside the operating room where constant noise, anesthetic vapors, ionizing radiation, infectious ag...

    Authors: Daniel Dongiu Kim, Aldemar Kimura Jr, Dayanne Karla Lopes Pontes, Maycon Luiz Silva Oliveira and Debora Oliveira Cumino

    Citation: BMC Anesthesiology 2018 18:193

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  15. Content type: Research article

    Central venous oxygen saturation (ScvO2), venous-arterial blood carbon dioxide partial pressures difference (Pv-aCO2), venous-arterial blood carbon dioxide partial pressures difference/arterial-venous oxygen diff...

    Authors: Xiang-yu Wan, Li-li Wei, Yan Jiang, Ping Li and Bo Yao

    Citation: BMC Anesthesiology 2018 18:187

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  16. Content type: Research article

    Weaning post-cardiac surgery patients from mechanical ventilation (MV) poses a big challenge to these patients. Optimized left ventricular-arterial coupling (VAC) may be crucial for reducing the MV duration of...

    Authors: Xu Wang, Yun Long, Huaiwu He, Guangliang Shan, Rui Zhang, Na Cui, Hao Wang, Xiang Zhou, Xi Rui and Wanglin Liu

    Citation: BMC Anesthesiology 2018 18:184

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  17. Content type: Research article

    Successful resuscitation from asystole induced by bupivacaine requires the reestablishment of a sufficient coronary flow (CF) quickly. This study was designed to test whether levosimendan was superior to epine...

    Authors: Hongfei Chen, Fangfang Xia, Zhousheng Jin, Kejian Shi, Yun Xia, Le Liu, Thomas J. Papadimos, Xuzhong Xu and Limei Chen

    Citation: BMC Anesthesiology 2018 18:174

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  18. Content type: Research article

    Mortality in patients with acute respiratory distress syndrome (ARDS) remains high. These patients require mechanical ventilation strategies that include high positive end-expiratory pressure (PEEP). It remain...

    Authors: Lanqi Guo, Jianfeng Xie, Yingzi Huang, Chun Pan, Yi Yang, Haibo Qiu and Ling Liu

    Citation: BMC Anesthesiology 2018 18:172

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  19. Content type: Research article

    Tenascin-C is a pro-inflammatory glycoprotein with various biological functions. High expression of tenascin-C is found in inflammation, tissue remodeling, and autoimmune diseases. However, its expression and ...

    Authors: Weifang Yuan, Wei Zhang, Xiaofang Yang, Liyuan Zhou, Ziwei Hanghua and Kailiang Xu

    Citation: BMC Anesthesiology 2018 18:170

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  20. Content type: Research article

    Cavity effusion is common in patients with infectious diseases. However, the incidence rate and characteristics of serous cavity effusions (SCE) in septic patients are not clear to date. The objective of this ...

    Authors: Ling-Yu Xing, Jun Yin, Mian Shao, Yi-Lin Yang, Ke-Yong Li, Ming-Ming Xue, Su-Cheng Mu, Zhan Sun, Ya-Ping Zhang, Chen-Ling Yao, Xun Chu, Chao-Yang Tong and Zhen-Ju Song

    Citation: BMC Anesthesiology 2018 18:169

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  21. Content type: Research article

    Fluid overloading is detrimental to organ function and results in a poor prognosis. It is necessary to evaluate fluid responsiveness before fluid loading. We performed a systematic meta-analysis to evaluate th...

    Authors: Bo Yao, Jian-yu Liu and Yun-bo Sun

    Citation: BMC Anesthesiology 2018 18:168

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  22. Content type: Research article

    ECMO support is a final treatment modality for patients in the refractory cardiogenic arrest and postcardiotomy cardiogenic shock with an utmost importance. Eventhough it is linked to high mortality, its usage...

    Authors: İbrahim Mungan, Dilek Kazancı, Şerife Bektaş, Derya Ademoglu and Sema Turan

    Citation: BMC Anesthesiology 2018 18:152

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  23. Content type: Research article

    In Burkina Faso, demographics are changing and we are seeing a growing prevalence of older patients in intensive care units. Elderly people have increased health care needs but there is a lack of geriatric spe...

    Authors: M. Lankoandé, P. Bonkoungou, A. Simporé, G. Somda and R. A. F. Kabore

    Citation: BMC Anesthesiology 2018 18:118

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  25. Content type: Research article

    Patients undergoing liver transplantation (LT) can develop acute heart failure (HF) in the postoperative period despite having had a normal cardiac evaluation prior to surgery. End-stage liver disease is often...

    Authors: Sonal Sharma, Kunal Karamchandani, Ryan Wilson, Sean Baskin and Dmitri Bezinover

    Citation: BMC Anesthesiology 2018 18:102

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  27. Content type: Research article

    A major challenge in sepsis intervention is unclear risk stratification. We postulated that a panel of biomarkers of lymphocyte apoptosis and immune function, termed the “lymphocyte apoptosis model,” would be ...

    Authors: Wenqiang Jiang, Wenhong Zhong, Yiyu Deng, Chunbo Chen, Qiaosheng Wang, Maohua Zhou, Xusheng Li, Cheng Sun and Hongke Zeng

    Citation: BMC Anesthesiology 2018 18:89

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  28. Content type: Research article

    Acute liver injury in patients with ARDS decreases survival but early stages may be easily missed due to the lack of sufficient biomarkers signalling its onset. Accordingly, we tested in ARDS patients the hypo...

    Authors: Tim Rahmel, Katharina Rump, Michael Adamzik, Jürgen Peters and Ulrich H. Frey

    Citation: BMC Anesthesiology 2018 18:75

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  29. Content type: Case report

    Acute liver failure (ALF) is a life-threatening entity particularly when infectious complications worsen the clinical course. Urgent liver transplantation (LT) is frequently the only curative treatment. Howeve...

    Authors: Matthias Buechter, Guido Gerken, Dieter P. Hoyer, Stefanie Bertram, Jens M. Theysohn, Viktoria Thodou and Alisan Kahraman

    Citation: BMC Anesthesiology 2018 18:71

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  30. Content type: Research article

    Acute ethanol intoxication has been shown to have contrasting effects on outcomes in sepsis. The aim of this study was to explore the effects of acute ethanol intoxication on hemodynamics, renal function, brai...

    Authors: Koji Hosokawa, Fuhong Su, Fabio Silvio Taccone, Emiel Hendrik Post, Jacques Creteur and Jean-Louis Vincent

    Citation: BMC Anesthesiology 2018 18:70

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  31. Content type: Research article

    Intra-abdominal pressure (IAP) can be measured by several indirect methods; however, the urinary bladder is largely preferred. The aim of this study was to compare intra-bladder pressure (IBP) at different lev...

    Authors: Abdulla Ahmed Al-Abassi, Azan Saleh Al Saadi and Faisal Ahmed

    Citation: BMC Anesthesiology 2018 18:69

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  32. Content type: Research article

    Contribution of the small intestine to systemic inflammation after cardiac arrest (CA) is poorly understood. The objective was to evaluate whether an in vivo rat model of 6 min CA is suitable to initiate intes...

    Authors: Daniel C. Schroeder, Alexandra C. Maul, Esther Mahabir, Isabell Koxholt, Xiaowei Yan, Stephan A. Padosch, Holger Herff, Insa Bultmann-Mellin, Anja Sterner-Kock, Thorsten Annecke, Tim Hucho, Bernd W. Böttiger and Maria Guschlbauer

    Citation: BMC Anesthesiology 2018 18:61

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  33. Content type: Research article

    Functional hemodynamic parameters such as stroke volume and pulse pressure variation (SVV and PPV) have been shown to be reliable predictors of fluid responsiveness in mechanically ventilated patients. Today, ...

    Authors: Michael T. Ganter, Martin Geisen, Sonja Hartnack, Omer Dzemali and Christoph K. Hofer

    Citation: BMC Anesthesiology 2018 18:55

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  34. Content type: Research article

    The association of troponin-I levels and outcome in medical-surgical ICU patients has been studied before in populations with low to moderate prevalence of cardiovascular risk factors. The objective in this ar...

    Authors: Abdulaleem Alatassi, Mohamad Habbal, Hani Tamim, Musharaf Sadat, Eman Al Qasim and Yaseen M. Arabi

    Citation: BMC Anesthesiology 2018 18:54

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  36. Content type: Editorial

    Although significant advances in clinical monitoring technology and clinical practice development have taken place in the last several decades, in this editorial we argue that much more still needs to be done....

    Authors: D. John Doyle, Ashraf A. Dahaba and Yannick LeManach

    Citation: BMC Anesthesiology 2018 18:39

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    The Correction to this article has been published in BMC Anesthesiology 2018 18:58

  37. Content type: Research article

    The morbidity and mortality of acute respiratory distress syndrome (ARDS) remains high, and the strategic focus of ARDS research has shifted toward identifying patients at high risk of mortality early in the c...

    Authors: I-Chen Chen, Chew-Teng Kor, Ching-Hsiung Lin, Jane Kuo, Jang-Zern Tsai, Wen-Je Ko and Cheng-Deng Kuo

    Citation: BMC Anesthesiology 2018 18:34

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  38. Content type: Research article

    Stressful patient experiences during the intensive care unit (ICU) stay is associated with reduced satisfaction in High Income Countries (HICs) but has not been explored in Lower and Middle Income Countries (L...

    Authors: Lalitha Pieris, Ponsuge Chathurani Sigera, Ambepitiyawaduge Pubudu De Silva, Sithum Munasinghe, Aasiyah Rashan, Priyantha Lakmini Athapattu, Kosala Saroj Amarasiri Jayasinghe, Kerstein Samarasinghe, Abi Beane, Arjen M. Dondorp and Rashan Haniffa

    Citation: BMC Anesthesiology 2018 18:30

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  39. Content type: Research article

    Accurate measurement of esophageal pressure (Pes) depends on proper filling of the balloon. Esophageal wall elastance (Ees) may also influence the measurement. We examined the estimation of balloon-surrounding...

    Authors: Xiu-Mei Sun, Guang-Qiang Chen, Hua-Wei Huang, Xuan He, Yan-Lin Yang, Zhong-Hua Shi, Ming Xu and Jian-Xin Zhou

    Citation: BMC Anesthesiology 2018 18:21

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  40. Content type: Research article

    Argatroban or lepirudin anticoagulation therapy in patients with heparin induced thrombocytopenia (HIT) or HIT suspect is typically monitored using the activated partial thromboplastin time (aPTT). Although aP...

    Authors: Martin Beiderlinden, Patrick Werner, Astrid Bahlmann, Johann Kemper, Tobias Brezina, Maximilian Schäfer, Klaus Görlinger, Holger Seidel, Peter Kienbaum and Tanja A. Treschan

    Citation: BMC Anesthesiology 2018 18:18

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  41. Content type: Research article

    Ion channels play a crucial role in the development of ischemic brain injury. Recent studies have reported that the blockade of various types of ion channels improves outcomes in experimental stroke models. Am...

    Authors: Masakazu Kotoda, Tadahiko Ishiyama, Kazuha Mitsui, Sohei Hishiyama and Takashi Matsukawa

    Citation: BMC Anesthesiology 2017 17:168

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  42. Content type: Research article

    Previous studies have reported that the quality of cardiopulmonary resuscitation (CPR) is closely associated with patient outcomes. The aim of this study was to compare patient CPR outcomes across resident, em...

    Authors: Tak Kyu Oh, Young Mi Park, Sang-Hwan Do, Jung-Won Hwang and In-Ae Song

    Citation: BMC Anesthesiology 2017 17:166

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  43. Content type: Research article

    Although mortality after cardiac surgery has significantly decreased in the last decade, patients still experience clinically relevant postoperative complications. Among others, atrial fibrillation (AF) is a c...

    Authors: Hristo Todorov, Inka Janssen, Stefanie Honndorf, Daniela Bause, Antje Gottschalk, Silke Baasner, Thomas Volkert, Valentin Faerber, John F. Stover, Martin Westphal and Björn Ellger

    Citation: BMC Anesthesiology 2017 17:163

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  45. Content type: Research article

    Lung protective mechanical ventilation with limited peak inspiratory pressure has been shown to affect cardiac output in patients with ARDS. However, little is known about the impact of lung protective mechani...

    Authors: Rudolf Hering, Stefan Kreyer and Christian Putensen

    Citation: BMC Anesthesiology 2017 17:149

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  46. Content type: Editorial

    While the long-term negative effects of obesity on health is a well-studied phenomenon, its effects on acute illnesses seem to be the contrary. Several studies have indicated the possibility of an ‘obesity par...

    Authors: Pauline Yeung Ng and Matthias Eikermann

    Citation: BMC Anesthesiology 2017 17:147

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  47. Content type: Technical advance

    Hemodynamic resuscitation in septic shock requires aggressive fluid replacement and appropriate use of vasopressors to optimize arterial pressure (AP) and cardiac output (CO). Because responses to these drugs ...

    Authors: Kazunori Uemura, Toru Kawada, Can Zheng, Meihua Li and Masaru Sugimachi

    Citation: BMC Anesthesiology 2017 17:145

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  48. Content type: Research article

    Traditionally, technical proficiency for spinal anesthesia has been assessed using observational scales such as global rating scales or task specific checklists. However more objective metrics are required in ...

    Authors: Marcia A. Corvetto, Carlos Fuentes, Andrea Araneda, Pablo Achurra, Pablo Miranda, Paola Viviani and Fernando R. Altermatt

    Citation: BMC Anesthesiology 2017 17:131

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  49. Content type: Research article

    The majority of critically ill patients experience distress during their stay in the Intensive Care Unit (ICU), resulting from systemic illness, multiple interventions and environmental factors. Providing huma...

    Authors: Katarzyna Kotfis, Małgorzata Zegan-Barańska, Maciej Żukowski, Krzysztof Kusza, Mariusz Kaczmarczyk and E. Wesley Ely

    Citation: BMC Anesthesiology 2017 17:120

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  50. Content type: Research article

    The role of increased body mass index (BMI) in sepsis is controversial. We aimed to evaluate the associations between overweight (25 kg/m2 < BMI ≤ 29.9 kg/m2), obese (30 kg/m2 < BMI ≤ 39.9 kg/m2) and morbidly obe...

    Authors: Sicong Wang, Xu Liu, Qixing Chen, Can Liu, Changshun Huang and Xiangming Fang

    Citation: BMC Anesthesiology 2017 17:118

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