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Critical care

This section deals with all manuscripts related to critical care and ICU medicine.

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  1. The feasibility and safety of administrating a small amount of oral fluid to children in the early recovery period following tonsillectomy under general anesthesia to reduce the thirst and its associated restl...

    Authors: Meng-Hang Wu, Chang-qing Liu, Xiao-qi Zeng, An-na Jia and Xiao-rong Yin

    Citation: BMC Anesthesiology 2021 21:13

    Content type: Research article

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  2. Pneumonia induced by 2019 Coronavirus (COVID-19) is characterized by hypoxemic respiratory failure that may present with a broad spectrum of clinical phenotypes. At the beginning, patients may have normal lung...

    Authors: Michela Rauseo, Lucia Mirabella, Rosa Roberta Caporusso, Leonarda Pia Cantatore, Marco Paolo Perrini, Paolo Vetuschi, Daniela La Bella, Livio Tullo and Gilda Cinnella

    Citation: BMC Anesthesiology 2021 21:9

    Content type: Case report

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  3. In critically ill patients continuous EEG (cEEG) is recommended in several conditions. Recently, a new wireless EEG headset (CerebAir®,Nihon-Kohden) is available. It has 8 electrodes, and its positioning seems...

    Authors: Anselmo Caricato, Giacomo Della Marca, Eleonora Ioannoni, Serena Silva, Tiziana Benzi Markushi, Eleonora Stival, Daniele Guerino Biasucci, Nicola Montano, Camilla Gelormini and Isabella Melchionda

    Citation: BMC Anesthesiology 2020 20:298

    Content type: Research article

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  4. There are several scores used for in-hospital mortality prediction in critical illness. Their application in a local scenario requires validation to ensure appropriate diagnostic accuracy. Moreover, their use ...

    Authors: Szymon Czajka, Katarzyna Ziębińska, Konstanty Marczenko, Barbara Posmyk, Anna J. Szczepańska and Łukasz J. Krzych

    Citation: BMC Anesthesiology 2020 20:296

    Content type: Research article

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  5. It is not clear whether there are valuable inflammatory markers for prognosis judgment in the intensive care unit (ICU). We therefore conducted a multicenter, prospective, observational study to evaluate the p...

    Authors: Rong Qu, Linhui Hu, Yun Ling, Yating Hou, Heng Fang, Huidan Zhang, Silin Liang, Zhimei He, Miaoxian Fang, Jiaxin Li, Xu Li and Chunbo Chen

    Citation: BMC Anesthesiology 2020 20:292

    Content type: Research article

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  6. Up to 70% of septic patients develop a diffuse brain dysfunction named “septic associated encephalopathy” which is often solely based on clinical impressions. However, the diagnosis of septic associated enceph...

    Authors: Benedikt Zujalovic, Benjamin Mayer, Sebastian Hafner, Florian Balling and Eberhard Barth

    Citation: BMC Anesthesiology 2020 20:287

    Content type: Research article

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  7. Thiamine, an essential vitamin for aerobic metabolism and glutathione cycling, may decrease the effects of critical illnesses. The objective of this study was to determine whether intravenous thiamine administ...

    Authors: Suttasinee Petsakul, Sunthiti Morakul, Viratch Tangsujaritvijit, Parinya Kunawut, Pongsasit Singhatas and Pitsucha Sanguanwit

    Citation: BMC Anesthesiology 2020 20:280

    Content type: Research article

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  8. Early diagnosis of sepsis is very important. It is necessary to find effective and adequate biomarkers in order to diagnose sepsis. In this study, we compared the value of sialic acid and procalcitonin for dia...

    Authors: Bo Yao, Wen-juan Liu, Di Liu, Jin-yan Xing and Li-juan Zhang

    Citation: BMC Anesthesiology 2020 20:277

    Content type: Research article

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  9. In acute respiratory distress syndrome (ARDS), lung recruitment maneuvers can recruit collapsed alveoli in gravity-dependent lung regions, improving the homogeneity of ventilation distribution. This study used...

    Authors: Feiping Xia, Chun Pan, Lihui Wang, Ling Liu, Songqiao Liu, Fengmei Guo, Yi Yang and Yingzi Huang

    Citation: BMC Anesthesiology 2020 20:266

    Content type: Research article

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  10. The prognosis of hospitalized patients after emergent endotracheal intubation (ETI) remains poor. Our aim was to evaluate the 30-d hospitalization mortality of subjects undergoing ETI during daytime or off-hou...

    Authors: Jun-Le Liu, Jian-Wen Jin, Zhong-Meng Lai, Jie-Bo Wang, Jian-Sheng Su, Guo-Hua Wu, Wen-Hua Chen and Liang-Cheng Zhang

    Citation: BMC Anesthesiology 2020 20:265

    Content type: Research article

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  11. We sought to evaluate the effect of mild hypercapnia on brain tissue oxygen tension (Pbto2) and diffusion limitation (impaired ability of oxygen extraction) in a porcine post asphyxial cardiac arrest model.

    Authors: Dawei Zhou, Zhimin Li, Shaolan Zhang, Lei Wu, Yiyuan Li, Guangzhi Shi and Jianxin Zhou

    Citation: BMC Anesthesiology 2020 20:252

    Content type: Research article

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  12. Capillary refill time (CRT) is a non-invasive technique to evaluate tissue perfusion, and quantitative CRT (Q-CRT) adapted to pulse oximetry was developed with patients with sepsis and compared to blood lactat...

    Authors: Miyuki Yamamoto, Kent Doi, Naoki Hayase, Toshifumi Asada, Nobuhisa Akamatsu, Junichi Kaneko, Kiyoshi Hasegawa and Naoto Morimura

    Citation: BMC Anesthesiology 2020 20:251

    Content type: Research article

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  13. Most trauma patients admitted to the hospital alive and die later on, decease during the initial care in the emergency department or the intensive care unit (ICU). However, a number of patients pass away after...

    Authors: Uwe Hamsen, Niklas Drotleff, Rolf Lefering, Julius Gerstmeyer, Thomas Armin Schildhauer and Christian Waydhas

    Citation: BMC Anesthesiology 2020 20:243

    Content type: Research article

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  14. Sepsis often accompanies gastrointestinal motility disorder that contributes to the development of sepsis in turn. Propofol and dexmedetomidine, as widely used sedatives in patients with sepsis, are likely to ...

    Authors: Haiqing Chang, Shuang Li, Yansong Li, Hao Hu, Bo Cheng, Jiwen Miao, Hui Gao, Hongli Ma, Yanfeng Gao and Qiang Wang

    Citation: BMC Anesthesiology 2020 20:227

    Content type: Research article

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  15. Based on the previous investigation in our institution, the incidence of intraoperative hypothermia in neonates was high. Since September 1st, 2019, the recommendation had been launched to utilize ≤1 L/min fre...

    Authors: Yu Cui, Yu Wang, Rong Cao, Gen Li, Lingmei Deng and Jia Li

    Citation: BMC Anesthesiology 2020 20:223

    Content type: Research article

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  16. Arteriovenous fistulae (AVF) are the hemodialysis access modality of choice for patients with end-stage renal disease. However, they have a high early failure rate. Good vascular access is essential to manage ...

    Authors: Chen Gao, Chunyan Weng, Chenghai He, Jingli Xu and Liqiang Yu

    Citation: BMC Anesthesiology 2020 20:219

    Content type: Research article

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  17. Acute respiratory distress syndrome (ARDS) is a life-threatening condition and the identification of the underlying direct (pulmonary) or indirect (non-pulmonary) cause is mandatory for a successful treatment....

    Authors: Nils Theuerkauf, Tobias Weismüller, Carsten Weißbrich, Jens-Christian Schewe, Christian Putensen and Christian Bode

    Citation: BMC Anesthesiology 2020 20:182

    Content type: Case report

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  19. The objectives of the present study was to evaluate the effect of fluid challenge (FC) on ventriculo-arterial (V-A) coupling, its determinants: arterial elastance and ventricular elastance, and ability to pred...

    Authors: Pierre Huette, Osama Abou-Arab, Dan Longrois and Pierre-Grégoire Guinot

    Citation: BMC Anesthesiology 2020 20:171

    Content type: Research article

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  20. Individualized treatment is a common principle in hospitals. Treatment decisions are made based on the patient’s condition, including comorbidities. This principle is equally relevant out-of-hospital. Furtherm...

    Authors: Kristin Tønsager, Marius Rehn, Andreas J. Krüger, Jo Røislien and Kjetil G. Ringdal

    Citation: BMC Anesthesiology 2020 20:167

    Content type: Research article

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  21. The control of endothelial progenitor cells (CD133+/CD34+ EPCs) migrating from bone marrow to peripheral blood is not completely understood. Emerging evidence suggests that stromal cell-derived factor-1α (SDF-...

    Authors: Antonella Cotoia, Olga Cela, Gaetano Palumbo, Sabrina Altamura, Flavia Marchese, Nicoletta Mangialetto, Daniela La Bella, Vincenzo Lizzi, Nazzareno Capitanio and Gilda Cinnella

    Citation: BMC Anesthesiology 2020 20:158

    Content type: Research article

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  22. Peripheral perfusion index (PPI) is an indicator reflecting perfusion. Patients undergoing long time surgeries are more prone to hypoperfusion and increased lactate. Few studies focusing on investigating the a...

    Authors: Xinge Shi, Ming Xu, Xu Yu and Yibin Lu

    Citation: BMC Anesthesiology 2020 20:153

    Content type: Research article

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  23. There has been a global increase in the incidence of acute kidney injury (AKI), including among critically-ill surgical patients. AKI prediction score provides an opportunity for early detection of patients wh...

    Authors: Konlawij Trongtrakul, Jayanton Patumanond, Suneerat Kongsayreepong, Sunthiti Morakul, Tanyong Pipanmekaporn, Osaree Akaraborworn and Sujaree Poopipatpab

    Citation: BMC Anesthesiology 2020 20:140

    Content type: Research article

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  24. With the following report we want to present an unusual case of a patient suffering from acute respiratory distress syndrome with early discovery of bacterial pathogens in bronchoalveolar liquid samples that d...

    Authors: Stefanie Prohaska, Philipp Henn, Svetlana Wenz, Leonie Frauenfeld, Peter Rosenberger and Helene A. Haeberle

    Citation: BMC Anesthesiology 2020 20:107

    Content type: Case report

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  25. RESP score and PRESERVE score have been validated for veno-venous Extracorporeal Membrane Oxygenation in severe ARDS to assume individual mortality risk. ARDS patients with low-flow Extracorporeal Carbon Dioxi...

    Authors: Jan Petran, Thorsten Muelly, Rolf Dembinski, Niklas Steuer, Jutta Arens, Gernot Marx and Ruedger Kopp

    Citation: BMC Anesthesiology 2020 20:102

    Content type: Research article

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  26. INTELLiVENT-ASV® (I-ASV) is a closed-loop ventilation mode that automatically controls the ventilation settings. Although a number of studies have reported the usefulness of I-ASV, the clinical situations in whic...

    Authors: Shinshu Katayama, Ken Tonai, Jun Shima, Kansuke Koyama and Shin Nunomiya

    Citation: BMC Anesthesiology 2020 20:94

    Content type: Research article

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  28. Reports of anaesthetic management of paraganglioma resection in patients with isolated L-transposition of the great arteries (L-TGA) are rare. We focus on the preoperative evaluation, intraoperative management...

    Authors: Ling Lan, Penghao Liu, Yuan Tian, Bo Zhu, Le Shen and Yuguang Huang

    Citation: BMC Anesthesiology 2020 20:79

    Content type: Case report

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  29. There are many prognostic models and scoring systems in use to predict mortality in ICU patients. The only general ICU scoring system developed and validated for patients after cardiac surgery is the APACHE-IV...

    Authors: Abraham Schoe, Ferishta Bakhshi-Raiez, Nicolette de Keizer, Jaap T. van Dissel and Evert de Jonge

    Citation: BMC Anesthesiology 2020 20:65

    Content type: Research article

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  30. The “END-of-Life ScorING-System” (ENDING-S) was previously developed to identify patients at high-risk of dying in the ICU and to facilitate a practical integration between palliative and intensive care. The a...

    Authors: Gianluca Villa, Timothy Amass, Rosa Giua, Iacopo Lanini, Cosimo Chelazzi, Lorenzo Tofani, Rory McFadden, A. Raffaele De Gaudio, Sean OMahony, Mitchell M. Levy and Stefano Romagnoli

    Citation: BMC Anesthesiology 2020 20:63

    Content type: Research article

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  31. Catecholamines are the first-line vasopressors used in patients with septic shock. However, the search for novel drug candidates is still of great importance due to the development of adrenergic hyposensitivit...

    Authors: Lili Huang, Shi Zhang, Wei Chang, Feiping Xia, Songqiao Liu, Yi Yang and Haibo Qiu

    Citation: BMC Anesthesiology 2020 20:58

    Content type: Research article

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  32. The requirement of prolonged mechanical ventilation (PMV) is associated with increased medical care demand and expenses, high early and long-term mortality, and worse life quality. However, no study has assess...

    Authors: Yueming Sun, Shuangling Li, Shupeng Wang, Chen Li, Gang Li, Jiaxuan Xu, Hongzhi Wang, Fei Liu, Gaiqi Yao, Zhigang Chang, Yalin Liu, Meixia Shang and Dongxin Wang

    Citation: BMC Anesthesiology 2020 20:44

    Content type: Research article

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  33. There is little knowledge, whether in patients with sepsis neutrophil extracellular trap (NET) formation and NET degrading nuclease activity are altered. Thus, we tested the hypotheses that 1) NET formation fr...

    Authors: Linda E. Cox, Kai Walstein, Lena Völlger, Friederike Reuner, Alexandra Bick, Annika Dötsch, Andrea Engler, Jürgen Peters, Maren von Köckritz-Blickwede and Simon T. Schäfer

    Citation: BMC Anesthesiology 2020 20:15

    Content type: Research article

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  34. Intradialytic hypotension is a serious complication during renal replacement therapy in critically ill patients. Early prediction of intradialytic hypotension could allow adequate prophylactic measures. In thi...

    Authors: Hanan Mostafa, Mohamed Shaban, Ahmed Hasanin, Hassan Mohamed, Shymaa Fathy, Hossam M. Abdelreheem, Ahmed Lotfy, Ayman Abougabal, Ahmed Mukhtar and Akram El-adawy

    Citation: BMC Anesthesiology 2019 19:242

    Content type: Research article

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  35. Point-of-care (POC) hemoglobin testing has the potential to revolutionize massive transfusion strategies. No prior studies have compared POC and central laboratory testing of hemoglobin in patients undergoing ...

    Authors: Justin Herman, Brian Park, Bharat Awsare, Frances West, Denine Crittendon, Lilah Evans, Mary Harach, Julie Karp, Alexis Peedin, Marianna LaNoue, Barbara Goldsmith, Eugene Warnick and Michael Baram

    Citation: BMC Anesthesiology 2019 19:240

    Content type: Research article

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  36. Surgery and diseases modify inflammatory responses and the immune system. Anesthetic agents also have effects on the human immune system but the responses they induce may be altered or masked by the surgical p...

    Authors: Minna Kallioinen, Annalotta Scheinin, Mikael Maksimow, Jaakko Långsjö, Kaike Kaisti, Riikka Takala, Tero Vahlberg, Katja Valli, Marko Salmi, Harry Scheinin and Anu Maksimow

    Citation: BMC Anesthesiology 2019 19:222

    Content type: Research article

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  37. Some studies have been performed to assess the effects of levosimendan on cardiac function when administered to cardiac surgery patients with low cardiac output syndrome (LCOS) in the immediate postoperative p...

    Authors: Jose Luis Guerrero Orriach, I. Navarro Arce, P. Hernandez Rodriguez, A. Raigón Ponferrada, A. Malo Manso, M. Ramirez Aliaga, A. Ramirez Fernandez, J. J. Escalona Belmonte, I. Bellido Estevez, A. Gomez Luque, R. Barrera Serrano, C. S. Toledo Medina, M. Rubio Navarro and J. Cruz Mañas

    Citation: BMC Anesthesiology 2019 19:212

    Content type: Research article

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  38. Secondary infection has a higher incidence in septic patients and affects clinical outcomes. This study aims to investigate the clinical characteristics, risk factors, immune status and prognosis of secondary ...

    Authors: Yao Chen, Yanyan Hu, Jin Zhang, Yue Shen, Junling Huang, Jun Yin, Ping Wang, Ying Fan, Jianli Wang, Su Lu, Yilin Yang, Lei Yan, Keyong Li, Zhenju Song, Chaoyang Tong and Shilin Du

    Citation: BMC Anesthesiology 2019 19:185

    Content type: Research article

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  39. Central arterial pressure can be derived from analysis of the peripheral artery waveform. The aim of this study was to compare central arterial pressures measured from an intra-aortic catheter with peripheral ...

    Authors: Sabino Scolletta, Antoine Herpain, Salvatore Mario Romano, Fabio Silvio Taccone, Katia Donadello, Boris Lubicz, Federico Franchi, Keitiane Michele Kaefer, Enrico Polati, Jean-Louis Vincent and Daniel De Backer

    Citation: BMC Anesthesiology 2019 19:173

    Content type: Research article

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  40. The current study investigates the effect of bronchoscopy-guided percutaneous dilatational tracheostomy (PDT) on the evolution of respiratory acidosis depending on endotracheal tube (ET) sizes. In addition, th...

    Authors: Christian Karagiannidis, Michaela L. Merten, Leo Heunks, Stephan E. Strassmann, Simone Schäfer, Friederike Magnet and Wolfram Windisch

    Citation: BMC Anesthesiology 2019 19:147

    Content type: Research article

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  41. Risk of over-immunosuppression or immunization may mitigate the overall and long-term renal outcomes of kidney transplant recipients (KTR) admitted to the ICU in the modern era but remain poorly described. Thu...

    Authors: Damien Guinault, Arnaud Del Bello, Laurence Lavayssiere, Marie-Béatrice Nogier, Olivier Cointault, Nicolas Congy, Laure Esposito, Anne-Laure Hebral, Olivier Roques, Nassim Kamar and Stanislas Faguer

    Citation: BMC Anesthesiology 2019 19:130

    Content type: Research article

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  42. Hypophosphatemia generally occurs in Intensive Care Units (ICUs), but its impact is often ignored. The aim of this study was to investigate whether hypophosphatemia can be a risk factor for ICU 28-day mortality.

    Authors: Lichun Wang, Chaoxing Xiao, Lei Chen, Xiaofei Zhang and Qiuye Kou

    Citation: BMC Anesthesiology 2019 19:86

    Content type: Research article

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  43. In patients with paroxysmal nocturnal hemoglobinuria (PNH), the membrane-attack complex (MAC) formed on red blood cells (RBCs) causes hemolysis due to the patient’s own activated complement system by an infect...

    Authors: Yuko Kawamoto, Tasuku Nishihara, Aisa Watanabe, Kazuo Nakanishi, Taisuke Hamada, Amane Konishi, Naoki Abe, Sakiko Kitamura, Keizo Ikemune, Yuichiro Toda and Toshihiro Yorozuya

    Citation: BMC Anesthesiology 2019 19:83

    Content type: Case report

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  44. This study investigated the associations of fluctuations in serum chloride (Cl−) levels with 30-day mortality after intensive care unit (ICU) admission among critically ill patients.

    Authors: Hyo Jin Kim, Tak Kyu Oh, In-Ae Song and Jae Ho Lee

    Citation: BMC Anesthesiology 2019 19:79

    Content type: Research article

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  45. Extracorporeal membrane oxygenation (ECMO) is often used in critical patients with severe myocardial failure. However, the mortality rate of patients on ECMO is often high. Recent studies have suggested that e...

    Authors: Tsung-Yu Tsai, Kun-Hua Tu, Feng-Chun Tsai, Yu-Yun Nan, Pei-Chun Fan, Chih-Hsiang Chang, Ya-Chung Tian, Ji-Tseng Fang, Chih-Wei Yang and Yung-Chang Chen

    Citation: BMC Anesthesiology 2019 19:73

    Content type: Research article

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  46. Acute kidney injury (AKI) is strongly associated with high morbidity and mortality of critically ill patients. In the last years several different biological markers with higher sensitivity and specificity for...

    Authors: Laura Pasin, Sabrina Boraso and Ivo Tiberio

    Citation: BMC Anesthesiology 2019 19:62

    Content type: Research article

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  47. Sepsis and other infectious complications are major causes of mortality and morbidity in patients after cardiac surgery. Whereas conventional blood culture (BC) suffers from low sensitivity as well as a report...

    Authors: Kevin Pilarczyk, Peter-Michael Rath, Joerg Steinmann, Matthias Thielmann, Stephan A. Padosch, Max Dürbeck, Heinz Jakob and Fabian Dusse

    Citation: BMC Anesthesiology 2019 19:59

    Content type: Research article

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  48. A common postoperative complication found among patients who are critically ill is delirium, which has a high mortality rate. A predictive model is needed to identify high-risk patients in order to apply strat...

    Authors: Onuma Chaiwat, Mellada Chanidnuan, Worapat Pancharoen, Kittiya Vijitmala, Praniti Danpornprasert, Puriwat Toadithep and Chayanan Thanakiattiwibun

    Citation: BMC Anesthesiology 2019 19:39

    Content type: Research article

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    The Correction to this article has been published in BMC Anesthesiology 2019 19:58

  49. Extra Corporeal Membrane Oxygenation (ECMO) has become an accepted treatment option for severely ill patients. Due to a limited availability of ECMO support therapy, patients must often be transported to a spe...

    Authors: Stefan Felix Ehrentraut, Barbara Schroll, Stefan Lenkeit, Heidi Ehrentraut, Christian Bode, Stefan Kreyer, Florian Kögl, Felix Lehmann, Thomas Muders, Martin Scholz, Claudia Strater, Folkert Steinhagen, Nils Ulrich Theuerkauf, Carsten Weißbrich, Christian Putensen and Jens-Christian Schewe

    Citation: BMC Anesthesiology 2019 19:19

    Content type: Research article

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  50. This study aimed at developing and validating a scoring model to stratify critically ill patients after cardiac surgery based on risk for dysphagia, a common but often neglected complication.

    Authors: Xiao-Dong Zhou, Wei-Hua Dong, Chu-Huan Zhao, Xia-Fei Feng, Wei-Wei Wen, Wen-Yi Tu, Meng-Xing Cai, Tian-Cheng Xu and Qiang-Li Xie

    Citation: BMC Anesthesiology 2019 19:7

    Content type: Research article

    Published on:

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