Table 4 Univariate analysis of pediatric acute respiratory distress syndrome

Weight(kg)

7.3 (2.2)

7.5 (2.1)

0.075

Age(month)

9.1 (6.3)

9.9 (6.3)

0.038

Sex: n (%)

0.453

Male

29 (25.0)

87 (75.0)

Female

26 (27.7)

68 (72.3)

Intraoperative HMGB1(pg/mL)

11.6 (2.5)

9.1 (2.5)

< 0.001

Intraoperative HMGB1 in tertile(pg/mL)

1st

4 (5.7)

66 (94.3)

2nd

18 (26.1)

51 (73.9)

3rd

33 (46.5)

38 (53.5)

Intraoperative blood loss volume, (mL)

415.8 (176.4)

325.0 (144.8)

0.001

Pretransplant PELD score

20.3 (9.8)

17.2 (11.2)

0.115

Pretransplant hemoglobin (g/L)

94.5 (15.0)

95.8 (14.3)

0.635

Pretransplant creatinine(µmol/L)

14.2 (4.5)

14.6 (6.3)

0.681

Pretransplant albumin(g/L)

33.7 (4.0)

35.3 (5.0)

0.052

Pretransplant total bilirubin(µmol/L)

357.2 (192.8)

233.8 (150.7)

< 0.001

Pretransplant INR

1.6 (0.6)

1.6 (0.9)

0.468

Pretransplant HMGB1: (pg/mL)

0.9 (0.5)

1.0 (0.5)

0.453

Intraoperative anthepatic phase time(min)

47.5 (13.8)

46.8 (13.1)

0.685

Intraoperative fresh plasma transfusions(mL)

251.4 (194.2)

238.1 (183.5)

0.429

Surgery history: n (%)

0.315

 No

1(11.1)

8(88.9)

 Yes

54(26.9)

147(73.1)

Intraoperative RBC transfusions (in unit)

2.6 (1.2)

2.4 (1.0)

0.087

Intraoperative urine volume(mL)

459.3 (298.5)

472.8 (319.8)

0.853

Intraoperative infusion volume(mL)

1223.0 (525.6)

1217.8 (468.4)

0.442

Intraoperative surgery time(min)

503.0 (133.5)

484.1 (87.2)

0.263

Pretransplant WBC (×10⁹)

13.8 (5.9)

13.0 (7.5)

0.232

Graft cold ischemia time(min)

104.1 (34.9)

91.3 (39.6)

0.047

Pretransplant lactic acid(mmol/L)

3.7 (1.1)

3.7 (1.3)

0.863

Pretransplant blood ammonia(µmol/L)

65.9 (26.4)

65.0 (25.1)

0.772