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Table 1 Comparison of characteristics between obese and non-obese patients

From: The effect of positive end-expiratory pressure on intracranial pressure in obese and non-obese severe brain injury patients: a retrospective observational study

 

Total (n = 627)

Non-obese (n = 407)

Obese (n = 220)

P value

Age (years)

54 (38, 66)

54 (35, 66)

54 (44, 65)

0.355

Gender (male)

389 (62)

247 (61)

142 (65)

0.388

Weight (kg)

80 (68, 98)

73 (63, 80)

105 (93, 120)

< 0.001

Height (cm)

173 (165, 180)

171 (165, 180)

173 (165, 183)

0.035

BMI (kg/m2)

27 (24, 32)

25 (22, 27)

34 (32, 38)

< 0.001

Ethnicity

   

0.071

  Caucasian

457 (73)

287 (71)

170 (77)

 

  African American

71 (11)

47 (12)

24 (11)

 

  Hispanic

27 (4)

19 (5)

8 (4)

 

  Native American

8 (1)

4 (1)

4 (2)

 

  Other/Unknown

64 (11)

50 (13)

14 (6)

 

Lung Injury

   

< 0.001

  No

352 (56)

256 (63)

96 (44)

 

  Mild

118 (19)

70 (17)

48 (22)

 

  Moderate

119 (19)

58 (14)

61 (27)

 

  Severe

38 (6)

23 (6)

15 (7)

 

Cause of brain injury

   

0.07

  Traumatic brain injury

180 (29)

129 (32)

51 (23)

 

  Intracranial Hemorrhage

169 (27)

114 (28)

55 (25)

 

  Subarachnoid Hemorrhage

81 (13)

48 (12)

33 (15)

 

  Ischemic Stroke

51 (8)

29 (7)

22 (10)

 

  Brain tumor

30 (5)

16 (4)

14 (6)

 

  Subdural Hematoma

24 (4)

18 (4)

6 (3)

 

  Others

82 (15)

53 (13)

39 (18)

 

Categories of traumatic brain injury (n = 180)

   

0.984

  Head/only

66 (11)

47 (12)

19 (9)

 

  Head/multiple

70 (11)

50 (12)

20 (9)

 

  Head/other

44 (7)

32 (8)

12 (5)

 

GCS on admission

6 (3, 7)

6 (3, 7)

5 (3, 7)

0.791

APACHE IV score

78 (63, 93)

78 (63, 92)

79 (64, 96)

0.491

Invasive ventilation time (days)

7 (3, 13)

6 (3, 12)

7 (4, 13)

0.317

ICP monitoring time (days)

3 (1, 8)

3 (1, 8)

4 (1, 8)

0.535

Hypertonic saline

116 (19)

74 (18)

42 (19)

0.863

Mannitol

121 (19)

79 (19)

42 (19)

0.998

Vasopressors

328 (52)

212 (52)

116 (53)

0.945

ICU length of stay (hours)

250 (106, 424)

247 (105, 421)

253 (116, 425)

0.79

ICU mortality

158 (25)

96 (24)

62 (28)

0.243

Hospital mortality

210 (33)

126 (31)

84 (38)

0.082

  1. Data are median (interquartile range) or no./total (%)
  2. APACHE IV: Acute Physiology and Chronic Health Evaluation IV, BMI: body mass index, GCS: Glasgow Coma Scale, ICP: intracranial pressure, ICU: intensive care unit