Effect of different doses of esketamine compared with fentanyl combined with propofol on hypotension in patients undergoing painless abortion surgery: a prospective, randomized, double-blind controlled clinical trial

Table 3 Surgery time, anesthesia induction time, recovery time and dischargeable time, frequency of additional propofol dose, patient satisfaction, surgeon satisfaction and anesthesiologist satisfaction in the study

	Group F	Group EL	Group EM	Group EH	F/χ²	P-value ^a,b
Sample size, n	45	45	44	44
Mean surgery time (±SD) in (min)	10.33 ± 2.78	10.87 ± 3.20	10.24 ± 2.73	10.64 ± 1.75	0.516	0.672
Mean anesthesia induction time (±SD) in (min)	1.55 ± 0.17	1.51 ± 0.10	1.50 ± 0.11	1.50 ± 0.06	2.496	0.062
Mean recovery time (±SD) in (min)	10.11 ± 1.97	10.09 ± 2.91	9.90 ± 2.25	11.17 ± 1.64^*#$	2.897	0.037
Mean dischargeable time (±SD) in (min)	12.93 ± 1.84	12.67 ± 2.85	11.25 ± 1.31^*#	16.36 ± 2.97^*#$	37.530	0.000
Frequency of additional propofol, n (%)	12 (26.7%)	8 (17.8%)	4 (9.1%)^*	2 (4.5%)^*#	10.254	0.016
1	9 (20.0%)	8 (17.8%)	4 (9.1%)	2 (4.5%)^*#
2	3 (6.7%)	0(0%)	0 (0%)	0 (0%)
Patient satisfaction, n (%)	39 (86.7%)	42 (93.3%)	42 (95.5%)	36 (81.8%)	5.137	0.162
Surgeon satisfaction, n (%)	37 (82.2%)	37 (86.7%)	42 (95.5%)	39 (88.6%)	3.880	0.295
Anesthesiologist satisfaction, n (%)	37 (82.2%)	38(84.4%)	42 (95.5%)	36 (81.8%)	4.517	0.209

Abbreviations: SD Standard deviation, N number, Group F Fentanyl group, Group EL 0.2 mg/kg group Esketamine, Group EM 0.25 mg/kg Esketamine group, Group EH 0.3 mg/kg Esketamine group
^a P-value for group F compared with group EL, group EM and group EH. The symbol ^* Indicates statistically significant difference compared with group F, ^# indicates statistically significant difference compared with group EL, ^$ implies that the difference was statistically significant when compared with group EM
^b F test, Chi-square test and Fisher’s exact test were used for data analysis

ISSN: 1471-2253