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Fig. 3 | BMC Anesthesiology

Fig. 3

From: Glutamatergic neurons in paraventricular nucleus of the thalamus regulate the recovery from isoflurane anesthesia

Fig. 3

Neural dynamics of PVT in response to isoflurane. A Fluorescence calcium signals aligned to isoflurane-induced loss of righting reflex (LORR). B ΔF/F represents change in GCaMPs fluorescence from the mean level before the isoflurane is given. Mean (red trace) ± SEM (shading) indicating the average calcium transients during isoflurane-induced LORR. C Statistical chart of changes in Ca2+ signals in isoflurane -induced LORR. D Fluorescence calcium signals corresponded to isoflurane-induced recovery of righting reflex (RORR). E Mean (red trace) ± SEM (shading) indicating the average calcium transients during RORR. F Statistical chart of changes in Ca2+ signals during RORR. *P < 0.05, **P < 0.01, n = 10

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