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Table 1 Characteristics of the study patients according to the occurrence of postoperative AKI

From: Preoperative NT-proBNP and LVEF for the prediction of acute kidney injury after noncardiac surgery: a single-centre retrospective study

 

Overall

No AKI

AKI

 

Variables *

(n = 3314)

(n = 3091, 93.27%)

(n = 223, 6.72%)

P value

Age, yrs

67 (60, 73)

66 (60, 73)

70 (63, 75)

 < 0.001

Male sex

1729 (52.2)

1588 (51.4)

141 (63.2)

 < 0.001

BMI, kg/m2

22.86 (20.43, 25.40)

22.86 (20.44, 25.39)

22.50 (20.25, 25.62)

0.617

Medical history

 Hypertension

1161 (35.0)

1037 (33.5)

124 (55.6)

 < 0.001

 Diabetes

664 (20.0)

595 (19.2)

69 (30.9)

 < 0.001

 Coronary heart disease

217 (6.5)

175 (5.7)

42 (18.8)

 < 0.001

 Stroke

171 (5.2)

150 (4.9)

21 (9.4)

0.005

 Congestive heart failure

148 (4.5)

102 (3.3)

46 (20.6)

 < 0.001

 Ascites

25 (0.8)

21 (0.7)

4 (1.8)

0.145

 Use of RAAS inhibitors

424 (12.8)

365 (11.8)

59 (26.5)

 < 0.001

Preoperative laboratory findings

 eGFR, mL min−1 1.73 m2

89.40 (74.53, 105.70)

89.80 (75.50, 105.70)

80.80 (61.55, 106.70)

 < 0.001

 aProteinuria (≥ 1 +)

158 (4.8)

125 (4.0)

33 (14.8)

 < 0.001

 Haemoglobin, g l−1

124 .00(110.00, 136.00)

125.00 (110.00, 137.00)

117.00 (101.00, 131.50)

 < 0.001

 Serum albumin, g l−1

37.70 (34.70, 40.60)

37.80 (34.80, 40.60)

37.00 (33.65, 39.50)

0.001

 NT-proBNP, pg ml−1

76.36

(39.86, 178.47)

72.74

(38.84, 164.60)

163.10

(77.75, 913.50)

 < 0.001

 LVEF, %

66.00 (62.00, 70.80)

66.00 (62.00, 71.00)

61.00 (50.00, 67.15)

 < 0.001

Surgical characteristics

 Emergency surgery

82 (2.5)

66 (2.1)

16 (7.2)

 < 0.001

 Type of surgery

   

 < 0.001

 General

1330 (40.1)

1214 (39.3)

116 (52.0)

 

 Orthopaedic

1132 (34.2)

1059 (34.3)

73 (32.7)

 

 Thoracic

786 (23.7)

757 (24.5)

29 (13.0)

 

 Gynaecological

52 (1.6)

49 (1.6)

3 (1.3)

 

 Others

14 (0.4)

12 (0.4)

2 (0.9)

 

 Surgery duration, hrs

2.00 (2.00, 3.00)

2.00 (2.00, 3.00)

2.00 (2.00, 4.00)

0.069

 Major surgery

482 (14.5)

438 (14.2)

44 ( 19.7)

0.030

Type of anaesthesia

 General

2820 (85.1)

2626(85.0)

194 (87.0)

0.466

ASA physical status

 I

374 (11.3)

365 (11.8)

9 (4.0)

 

 II

2397 (72.3)

2273 (73.5)

124 (55.6)

 

 III

507 (15.3)

429 (13.9)

78 (35.0)

 

 IV

36 (1.1)

24 (0.8)

12 (5.4)

 
  1. Abbreviations: AKI Acute kidney injury, ASA American Society of Anesthesiologists, BMI Body mass index, eGFR Estimated glomerular filtration rate, IQR Interquartile range, NT-proBNP N-terminal pro-brain natriuretic peptide, RAAS Renin–angiotensin–aldosterone system
  2. *Categorical variables are shown as counts (percentages), and continuous variables are shown as medians (interquartile ranges)
  3. a Defined by a positive (≥ 1 +) urine dipstick test