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Table 6 Patients data according to MPV cutoff value

From: Mean platelet volume is useful for predicting weaning failure: a retrospective, observational study

Characteristics MPV > 11.3 fl
(n = 55)
MPV ≤ 11.3 fl
(n = 206)
P
Age, year (mean ± SD) 72.89 ± 11.64 70.79 ± 13.22 0.286
Male (n, %) 36(65.5) 114(55.3) 0.178
BMI, kg/m.2(mean ± SD) 24.29 ± 3.68 24.2 ± 4.73 0.894
APACHE II score on admission (mean ± SD) 21.13 ± 6.25 18.69 ± 6.98 0.019
IMV duration prior to weaning, days
[median(25th–75th percentiles)]
4(2–9) 3.5(2–7) 0.129
LOS during ICU, days
[median(25th–75th percentiles)]
17(9–28) 10(3–20) 0.001
LOS during hospital, days
[median(25th–75th percentiles)]
20(15–37) 18(13–28) 0.154
Cause of mechanical ventilation, n (%)
 Exacerbation of chronic respiratory disorders 11(20) 41(19.9) 0.987
 Pneumonia 21(38.2) 56(27.2) 0.112
 Sepsis 8(14.5) 30(14.6) 0.997
 Postoperation 10(18.2) 57(27.7) 0.152
 Congestive heart failure 3(5.5) 4(1.9) 0.164
 Neurological disease 2(3.6) 12(5.8) 0.741
 others 0(0) 6(2.9) 0.348
Comorbidity disease, n (%)
 Hypertension 30(54.5) 114(55.3) 0.916
 Diabetes Mellitus 19(34.5) 55(26.7) 0.251
 Chronic heart disorders 21(38.2) 62(30.1) 0.253
 Chronic respiratory disorders 18(32.7) 59(28.6) 0.555
 Malignancy 15(27.3) 46(22.3) 0.442
 Chronic kidney disease 7(12.7) 22(10.7) 0.668
 Cerebrovascular disease 10(18.2) 33(16.0) 0.701
 Immunosuppression 3(5.5) 1(0.5) 0.030
Vital signs
 RR, breaths/min 20(16–24) 20(16–23) 0.526
 SpO2, % 98(97–100) 99(97.7–100) 0.041
 HR, beats/min 86(75–102) 86(78–98) 0.747
 SPB, mmHg 129(116–138) 130(118–144) 0.440
Arterial blood gas
 PH 7.45(7.42–7.48) 7.45(7.42–7.48) 0.908
 PaCO2, mmHg 41.9(35–48) 38(34–45) 0.076
 PaO2,mmHg 90(76–121) 96(80.8–125.3) 0.162
 PaO2/FiO2, mmHg 265.7(220.6–362.5) 295.3(233.7–295.3) 0.201
 Leukocyte count, × 10.9/L 9.8(7.6–11.8) 9.1(6.7–12.5) 0.613
 Platelet count, × 109/L 152(108–196) 186(140–254) 0.001
 PDW, % 15.2(12.7–17.0) 11.8(10.5–12.9) 0.000
 Larger platelet ratio, % 38.5(34.6–43.4) 27.1(20.98–31.43) 0.000
 CRP, mg/L 72(29–105) 45.5(18–85) 0.025
  1. Continuous variables were presented as median and interquartile range (IQR) or (mean ± standard deviation, SD). Categorical variables were presented as numbers
  2. (n) and percentages (%). Difference of sex, cause of mechanical ventilation, and comorbidity disease between the groups were compared by Chi square (χ2) test. Difference of age, BMI and APACHE II score were compared by Student’s t test. Difference of other variables were compared by Mann–Whitney U-test
  3. Abbreviation: BMI Body Mass Index, APACHE II Acute Physiology And Chronic Health Evaluation II, IMV Invasive Mechanical Ventilation, LOS Length Of Stay, RR Respiratory Rate, HR Heart Rate, SBP Systolic Blood Pressure, SPO2 Peripheral Oxygen Saturation, PaCO2 arterial Carbon Dioxide tension, PaO2 arterial Oxygen tension, FiO2 Fraction of Inspired Oxygen, MPV Mean Platelet Volume, PDW Platelet Distribution Width, CRP C-reactive Protein