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Table 6 Patients data according to MPV cutoff value

From: Mean platelet volume is useful for predicting weaning failure: a retrospective, observational study

Characteristics

MPV > 11.3 fl

(n = 55)

MPV ≤ 11.3 fl

(n = 206)

P

Age, year (mean ± SD)

72.89 ± 11.64

70.79 ± 13.22

0.286

Male (n, %)

36(65.5)

114(55.3)

0.178

BMI, kg/m.2(mean ± SD)

24.29 ± 3.68

24.2 ± 4.73

0.894

APACHE II score on admission (mean ± SD)

21.13 ± 6.25

18.69 ± 6.98

0.019

IMV duration prior to weaning, days

[median(25th–75th percentiles)]

4(2–9)

3.5(2–7)

0.129

LOS during ICU, days

[median(25th–75th percentiles)]

17(9–28)

10(3–20)

0.001

LOS during hospital, days

[median(25th–75th percentiles)]

20(15–37)

18(13–28)

0.154

Cause of mechanical ventilation, n (%)

 Exacerbation of chronic respiratory disorders

11(20)

41(19.9)

0.987

 Pneumonia

21(38.2)

56(27.2)

0.112

 Sepsis

8(14.5)

30(14.6)

0.997

 Postoperation

10(18.2)

57(27.7)

0.152

 Congestive heart failure

3(5.5)

4(1.9)

0.164

 Neurological disease

2(3.6)

12(5.8)

0.741

 others

0(0)

6(2.9)

0.348

Comorbidity disease, n (%)

 Hypertension

30(54.5)

114(55.3)

0.916

 Diabetes Mellitus

19(34.5)

55(26.7)

0.251

 Chronic heart disorders

21(38.2)

62(30.1)

0.253

 Chronic respiratory disorders

18(32.7)

59(28.6)

0.555

 Malignancy

15(27.3)

46(22.3)

0.442

 Chronic kidney disease

7(12.7)

22(10.7)

0.668

 Cerebrovascular disease

10(18.2)

33(16.0)

0.701

 Immunosuppression

3(5.5)

1(0.5)

0.030

Vital signs

 RR, breaths/min

20(16–24)

20(16–23)

0.526

 SpO2, %

98(97–100)

99(97.7–100)

0.041

 HR, beats/min

86(75–102)

86(78–98)

0.747

 SPB, mmHg

129(116–138)

130(118–144)

0.440

Arterial blood gas

 PH

7.45(7.42–7.48)

7.45(7.42–7.48)

0.908

 PaCO2, mmHg

41.9(35–48)

38(34–45)

0.076

 PaO2,mmHg

90(76–121)

96(80.8–125.3)

0.162

 PaO2/FiO2, mmHg

265.7(220.6–362.5)

295.3(233.7–295.3)

0.201

 Leukocyte count, × 10.9/L

9.8(7.6–11.8)

9.1(6.7–12.5)

0.613

 Platelet count, × 109/L

152(108–196)

186(140–254)

0.001

 PDW, %

15.2(12.7–17.0)

11.8(10.5–12.9)

0.000

 Larger platelet ratio, %

38.5(34.6–43.4)

27.1(20.98–31.43)

0.000

 CRP, mg/L

72(29–105)

45.5(18–85)

0.025

  1. Continuous variables were presented as median and interquartile range (IQR) or (mean ± standard deviation, SD). Categorical variables were presented as numbers
  2. (n) and percentages (%). Difference of sex, cause of mechanical ventilation, and comorbidity disease between the groups were compared by Chi square (χ2) test. Difference of age, BMI and APACHE II score were compared by Student’s t test. Difference of other variables were compared by Mann–Whitney U-test
  3. Abbreviation: BMI Body Mass Index, APACHE II Acute Physiology And Chronic Health Evaluation II, IMV Invasive Mechanical Ventilation, LOS Length Of Stay, RR Respiratory Rate, HR Heart Rate, SBP Systolic Blood Pressure, SPO2 Peripheral Oxygen Saturation, PaCO2 arterial Carbon Dioxide tension, PaO2 arterial Oxygen tension, FiO2 Fraction of Inspired Oxygen, MPV Mean Platelet Volume, PDW Platelet Distribution Width, CRP C-reactive Protein