From: Mean platelet volume is useful for predicting weaning failure: a retrospective, observational study
Characteristics | MPV > 11.3 fl (n = 55) | MPV ≤ 11.3 fl (n = 206) | P |
---|---|---|---|
Age, year (mean ± SD) | 72.89 ± 11.64 | 70.79 ± 13.22 | 0.286 |
Male (n, %) | 36(65.5) | 114(55.3) | 0.178 |
BMI, kg/m.2(mean ± SD) | 24.29 ± 3.68 | 24.2 ± 4.73 | 0.894 |
APACHE II score on admission (mean ± SD) | 21.13 ± 6.25 | 18.69 ± 6.98 | 0.019 |
IMV duration prior to weaning, days [median(25th–75th percentiles)] | 4(2–9) | 3.5(2–7) | 0.129 |
LOS during ICU, days [median(25th–75th percentiles)] | 17(9–28) | 10(3–20) | 0.001 |
LOS during hospital, days [median(25th–75th percentiles)] | 20(15–37) | 18(13–28) | 0.154 |
Cause of mechanical ventilation, n (%) | |||
Exacerbation of chronic respiratory disorders | 11(20) | 41(19.9) | 0.987 |
Pneumonia | 21(38.2) | 56(27.2) | 0.112 |
Sepsis | 8(14.5) | 30(14.6) | 0.997 |
Postoperation | 10(18.2) | 57(27.7) | 0.152 |
Congestive heart failure | 3(5.5) | 4(1.9) | 0.164 |
Neurological disease | 2(3.6) | 12(5.8) | 0.741 |
others | 0(0) | 6(2.9) | 0.348 |
Comorbidity disease, n (%) | |||
Hypertension | 30(54.5) | 114(55.3) | 0.916 |
Diabetes Mellitus | 19(34.5) | 55(26.7) | 0.251 |
Chronic heart disorders | 21(38.2) | 62(30.1) | 0.253 |
Chronic respiratory disorders | 18(32.7) | 59(28.6) | 0.555 |
Malignancy | 15(27.3) | 46(22.3) | 0.442 |
Chronic kidney disease | 7(12.7) | 22(10.7) | 0.668 |
Cerebrovascular disease | 10(18.2) | 33(16.0) | 0.701 |
Immunosuppression | 3(5.5) | 1(0.5) | 0.030 |
Vital signs | |||
RR, breaths/min | 20(16–24) | 20(16–23) | 0.526 |
SpO2, % | 98(97–100) | 99(97.7–100) | 0.041 |
HR, beats/min | 86(75–102) | 86(78–98) | 0.747 |
SPB, mmHg | 129(116–138) | 130(118–144) | 0.440 |
Arterial blood gas | |||
PH | 7.45(7.42–7.48) | 7.45(7.42–7.48) | 0.908 |
PaCO2, mmHg | 41.9(35–48) | 38(34–45) | 0.076 |
PaO2,mmHg | 90(76–121) | 96(80.8–125.3) | 0.162 |
PaO2/FiO2, mmHg | 265.7(220.6–362.5) | 295.3(233.7–295.3) | 0.201 |
Leukocyte count, × 10.9/L | 9.8(7.6–11.8) | 9.1(6.7–12.5) | 0.613 |
Platelet count, × 109/L | 152(108–196) | 186(140–254) | 0.001 |
PDW, % | 15.2(12.7–17.0) | 11.8(10.5–12.9) | 0.000 |
Larger platelet ratio, % | 38.5(34.6–43.4) | 27.1(20.98–31.43) | 0.000 |
CRP, mg/L | 72(29–105) | 45.5(18–85) | 0.025 |