Mean platelet volume is useful for predicting weaning failure: a retrospective, observational study

BMC Anesthesiology

Table 1 Baseline characteristics

Characteristics	Weaning failure(n = 54)	Weaning success(n = 207)	P
Age, year (mean ± SD)	73.0 ± 10.9	70.7 ± 13.4	0.261
Male (n, %)	35(64.8)	115(55.6)	0.220
BMI, kg/m.²(mean ± SD)	24.8 ± 3.58	24.06 ± 4.73	0.260
APACHE II score on admission (mean ± SD)	21.7 ± 7.0	18.5 ± 6.7	0.004
IMV duration prior to weaning, days (median, 25th–75th percentiles)	6(3–12)	3(2–7)	0.000
Cause of mechanical ventilation, n (%)
Exacerbation of chronic respiratory disorders	13(24.1)	39(18.8)	0.391
Pneumonia	19(35.2)	58(28.0)	0.304
Sepsis	8(14.8)	30(14.5)	0.952
Postoperation	6(11.1)	61(29.5)	0.006
Congestive heart failure	2(3.7)	5(2.4)	0.637
Neurological disease	4(7.4)	10(4.8)	0.497
others	2(3.7)	4(1.9)	0.276
Comorbidity disease, n (%)
Hypertension	26(48.1)	118(57)	0.244
Diabetes Mellitus	17(31.5)	57(27.5)	0.567
Chronic heart disorders	18(33.3)	65(31.4)	0.786
Chronic respiratory disorders	13(24.1)	64(30.9)	0.326
Malignancy	15(27.8)	46(22.2)	0.390
Chronic kidney disease	7(13.0)	22(10.6)	0.627
Cerebrovascular disease	8(14.8)	35(16.9)	0.172
Immunosuppression	2(3.7)	2(1.0)	0.190

Continuous variables were presented as median and interquartile range (IQR) or (mean ± standard deviation, SD). Categorical variables were presented as numbers
(n) and percentages (%). Difference of sex, cause of mechanical ventilation, and comorbidity disease between the groups were compared by Chi square (χ2) test. Difference of age, BMI and APACHE II score were compared by Student’s t test. Difference of IMV duration prior to weaning were compared by Mann–Whitney U-test
Other causes of mechanical ventilation included acute pulmonary embolism(n = 1) and gastrointestinal bleeding(n = 1) in weaning failure group; and cardiac rest(n = 1) and gastrointestinal bleeding(n = 1) and trauma(n = 1) and hepatic encephalopathy(n = 1) in weaning success group
Abbreviation: BMI Body Mass Index, IMV Invasive Mechanical Ventilation, APACHE II Acute Physiology and Chronic Health Evaluation II

ISSN: 1471-2253