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Table 2 Procedure-level Characteristics: Late Postoperative Respiratory Failure compared to No Postoperative Respiratory Failure

From: Outcomes and risk factors for delayed-onset postoperative respiratory failure: a multi-center case-control study by the University of California Critical Care Research Collaborative (UC3RC)

Variablea

Total Sample

(n = 190)

No PRF

(n = 95)

L-PRF

(n = 95)

Unadjusted Odds Ratio

(95% CI)

Procedure

 General Anesthesia, n (%)

186 (97.9)

92 (96.8)

94 (98.9)

3.67 (0.32–41.78)

 Neuromuscular Blockade, n (%)

178 (93.7)

87 (91.6)

91 (95.8)

2.33 (0.60–9.02)

 Anesthesia duration per hour, median (IQR)

6.4 (4.4, 8.1)

5.5 (3.9, 7.1)

7.1 (4.7, 8.9)

1.23 (1.09–1.41)

 Surgical duration per hour, median (IQR)

4.6 (3.0, 6.5)

3.8 (2.7, 5.6)

5.3 (3.3, 7.2)

1.21 (1.07–1.39)

Intraoperative Ventilator Management

 Tidal Volume (highest) (cc/kg) predicted body weight, median (IQR)

8.8 (7.9, 9.9)

8.8 (7.9, 9.9)

8.9 (7.8, 10.3)

1.13 (0.95–1.34)

 Positive End Expiratory Pressure (highest), median (IQR)

5 (5, 6)

5 (5, 6)

5 (5, 8)

1.09 (0.95–1.26)

 Peak Inspiratory Pressure (highest), median (IQR)

23 (19, 28)

21 (18, 25.5)

25 (20, 29)

1.14 (1.07–1.21)

Intraoperative Fluid Management

 Crystalloid Administered (per 1000 cc), median (IQR)

2.2 (1.5, 3.2)

2 (1.4, 3)

2.5 (1.6, 3.5)

1.24 (0.99–1.55)

 Colloid Administered (per 250 cc), median (IQR)

0 (0, 4)

0 (0, 2)

1 (0, 4)

1.10 (1.01–1.20)

 Blood Transfused (per 250 cc), median (IQR)

0 (0, 1)

0 (0, 0)

0 (0, 2)

1.02 (0.99–1.05)

 Net Fluid in first 24 hours post-op (cc/kg), median (IQR)

24.4 (8.6, 47.0)

21.2 (7.9, 37.8)

26.6 (9.2, 65.5)

1.007 (1.0003–1.01)

  1. aRefer to Additional file 5, Table S5. Definitions of Comorbidities, Risk Factors, and Outcome Variables