Table 1 Demographics and clinical characteristics of study cohort
Characteristics | Non-LLT Group | LLT Group | p-value | PS adjusted Non-LLT | PS adjusted LLT | p-value |
|---|---|---|---|---|---|---|
Age(years), Mean [SD] | 65.5(12.1) | 66.4(10.7) | 0.231 | 66.4(11.3) | 66.0(10.8) | 0.394 |
Female, N (%) | 225(29.5) | 778(24.1) | 0.003 | 1060(26.1) | 1002(25.2) | 0.637 |
BMI, Mean [SD] | 28.7(8.4) | 29.5(7.5) | 0.007 | 29.1(5.9) | 29.2(5.9) | 0.778 |
Diabetes, N (%) | 231(30.2) | 1361(42.2) |  < 0.001 | 1675(41.3) | 1593(40.0) | 0.591 |
Renal Failure, N (%) | 47(6.2) | 169(5.2) | 0.363 | 211(5.2) | 214(5.4) | 0.861 |
Dialysis, N (%) | 32(4.2) | 120(3.7) | 0.617 | 151(3.7) | 151(3.8) | 0.943 |
Hypertension, N (%) | 556(72.8) | 2755(85.5) |  < 0.001 | 3378(83.3) | 3308(83.1) | 0.896 |
Smoking, N (%) | 359(47.0) | 1645(51.0) | 0.049 | 2025(49.9) | 1993(50.0) | 0.957 |
Chronic lung disease, N (%) | 132(17.3) | 532(16.5) | 0.643 | 631(15.6) | 660(16.6) | 0.539 |
Peripheral arterial disease, N (%) | 87(11.4) | 497(15.4) | 0.006 | 636(15.7) | 584(14.7) | 0.593 |
Cerebrovascular disease, N (%) | 91(11.9) | 587(18.2) |  < 0.001 | 720(17.8) | 678(17.0) | 0.717 |
Creatinine, Mean [SD] | 1.26(1.16) | 1.23(1.04) | 0.523 | 1.24(1.06) | 1.23(1.07) | 0.885 |
Previous cardiac surgery, N (%) | 17(2.2) | 139(4.3) | 0.010 | 177(4.4) | 157(3.9) | 0.718 |
Previous MI, N (%) | 253(33.1) | 1482(46.0) |  < 0.001 | 1763(43.4) | 1728(43.4) | 0.985 |
Previous heart failure, N (%) | 206(27.0) | 811(25.2) | 0.325 | 1007(24.8) | 1009(25.3) | 0.792 |
Cardiogenic shock, N (%) | 25(3.3) | 51(1.6) | 0.003 | 75(1.8) | 75(1.9) | 0.942 |
ACEI. ARB treatment, N (%) | 297(38.9) | 1568(48.6) |  < 0.001 | 1986(48.9) | 1872(47.0) | 0.410 |
Aspirin treatment, N (%) | 547(71.6) | 2853(88.5) |  < 0.001 | 3500(86.3) | 3403(85.5) | 0.519 |
β-blocker treatment, N (%) | 485(63.5) | 2573(79.8) |  < 0.001 | 3136(77.3) | 3058(76.8) | 0.776 |
EF < , Mean [SD] | 50.2(14.49) | 51.03(13.62) | 0.132 | 51.1(13.3) | 50.9(13.8) | 0.719 |
Valve procedure, N (%) | 239(31.3) | 705(21.9) |  < 0.001 | 911(22.4) | 938.2(23.6) | 0.536 |
Other cardiac surgery, N (%) | 85(11.1) | 273(8.5) | 0.025 | 325(8.0) | 353(8.9) | 0.449 |
CPB time, Mean [SD] | 136.7(78.9) | 132.0(71.4) | 0.109 | 134.2(76.6) | 132.7(72.1) | 0.685 |
Clamp time, Mean [SD] | 97.6(61.8) | 92.7(54.5) | 0.028 | 94.8(61.2) | 93.2(54.9) | 0.583 |