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Table 4 Postoperative outcomes

From: Desflurane improves lung collapse more than propofol during one-lung ventilation and reduces operation time in lobectomy by video-assisted thoracic surgery: a randomized controlled trial

Outcomes

Desflurane group

Propofol group

Relative risk (95% CI)

P value

N = 26

N = 24

Adverse event

 Pneumonia, n/total N (%)

1/26 (3%)

2/24 (8%)

0.46 (0.04 to 4.77)

0.60a

 Atelectasis, n/total N (%)

4/26 (15%)

5/24 (20%)

0.73 (0.22 to 2.43)

0.72a

 Surgical revision, n/total N (%)

0/26 (0%)

2/24 (8%)

N/A

0.22a

 Fistula, n/total N (%)

1/26 (3%)

1/24 (4%)

0.92 (0.06 to 13.95)

1.00a

 Effusion, n/total N (%)

1/26 (3%)

2/24 (8%)

0.46 (0.04 to 4.77)

0.60a

 Surgical sight infection, n/total N (%)

1/26 (3%)

3/24 (12%)

0.30 (0.03 to 2.76)

0.34a

 Reintubation, n/total N (%)

0/26 (0%)

2/24 (8%)

N/A

0.22a

 SIRS, n/total N (%)

1/26 (3%)

5/24 (20%)

0.18 (0.02 to 1.46)

0.09a

 Post-extubation hypoxemia,

n/total N (%)

0/26 (0%)

4/24 (16%)

N/A

0.04a

 Death, n/total N (%)

0/26 (0%)

0/24 (0%)

N/A

N/A

 Total, n/total N (%)

9

26

  

 Multiple adverse events, n/total N (%)

1/26 (3%)

6/24 (25%)

0.15 (0.02 to 1.18)

0.04a

 5-year postoperative recurrence, n/total N (%)

8/26 (30%)

7/24 (29%)

1.05 (0.45 to 2.46)

1.00a

 5-year postoperative death,

n/total N (%)

2/26 (7%)

4/24 (16%)

0.46 (0.09 to 2.29)

0.40a

   

The difference in Means (95% CI)

 

Hospital stay (days), mean (SD)

13 (14)

18 (22)

-5.5 (-16.3 to 5.2)

0.30b

Postoperative recurrence-free period (months), mean (SD)

48.5 (3.8)

48.2 (4.3)

N/A

0.98c

Postoperative survival period (months), mean (SD)

56.9 (2.1)

55.8 (2.3)

N/A

0.33c

  1. Relative risks are for Desflurane group relative to Propofol group; differences are (Desflurane group – Propofol group)
  2. SIRS Systemic inflammatory response syndrome, CI confidence interval, SD standard devision, N/A Not available
  3. aFisher's exact test
  4. bStudent's t-test
  5. cP-value from log-rank test