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Table 3 Intraoperative Lung Collapse Score and other outcomes

From: Desflurane improves lung collapse more than propofol during one-lung ventilation and reduces operation time in lobectomy by video-assisted thoracic surgery: a randomized controlled trial

 

Desflurane group

Propofol group

Difference in Means

P-value

N = 26

N = 24

(95% CI)

Lung Collapse Score (LCS)

 LCS10: 10 min after the initiation of OLV, mean (SD)

2.0 (0.4)

1.9 (0.5)

0.0 (-0.2 to 0.2)

0.85

 LCS30: 30 min after the initiation of OLV, mean (SD)

3.4 (0.6)

3.0 (0.6)

0.3 (0.0 to 0.6)

0.03

 LCS60: 60 min after the initiation of OLV, mean (SD)

4.5 (0.6)

4.1 (0.6)

0.4 (0.1 to 0.7)

0.00

 Operation time (min), mean (SD)

215 (58)

263 (72)

-48 (-85 to -11)

0.01

 Amount of bleeding (mL), mean (SD)

59 (73)

135 (159)

-75 (-148 to -6)

0.04

PaO2 (mmHg)

 Before OLV, mean (SD)

492 (52)

457 (82)

35 (-3 to 74)

0.07

 10 min after initiation of OLV, mean (SD)

227 (87)

194 (116)

33 (-25 to 91)

0.25

 30 min after initiation of OLV, mean (SD)

216 (81)

171 (110)

45 (-9 to 100)

0.1

 60 min after initiation of OLV, mean (SD)

183 (72)

154 (68)

29 (-11 to 69)

0.15

White blood cells (count × 103/μl)

 Before surgery, mean (SD)

5.2 (1.5)

6.1 (2.0)

-0.8 (-1.8 to 0.1)

0.08

 Postoperative day 1, mean (SD)

10.3 (3.5)

10.2 (3.4)

0.0 (-1.9 to 2.0)

0.94

 Postoperative day 3, mean (SD)

9.1 (2.3)

9.0 (1.8)

0.1 (-0.9 to 1.3)

0.74

C-reactive protein (mg/dl)

 Before surgery, mean (SD)

0.1 (0.1)

0.2 (0.4)

-0.1 (-0.2 to 0.0)

0.25

 Postoperative day 1, mean (SD), mean (SD)

3.8 (1.7)

4.0 (1.7)

-0.1 (-1,1 to 0.7)

0.69

 Postoperative day 3, mean (SD)

4.3 (3.3)

5.7 (4.5)

-1.3 (-3.5 to 0.8)

0.23

  1. Differences are (Desflurane group – Propofol group)
  2. Student's t-test was used for all tests
  3. LCS Lung Collapse Score, OLV one-lung ventilation, CI confidence interval, SD standard devision