Fig. 3
From: Pharmacodynamics, toxicology and toxicokinetics of ropivacaine oil delivery depot
Blocking effects of RODD on nerve conduction. n = 6 (male). *P < 0.05, **P < 0.01 vs saline group, #P < 0.05, ##P < 0.01 vs RAI 0.9 mg group. The nerve block effect of RAI 0.9 mg and RODD 3 mg was significant in 1 h after administration. After 2⁓3 h, the nerve block of RAI group gradually disappeared. RODD 3 mg inhibited nerve conduction for about 20 h, and the inhibition gradually disappeared. RODD 0.9 mg and solvent did no inhibit nerve conduction