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Table 4 First set of sensitivity analyses. Multivariable regression analyses with 95% confidence interval for odds or hazard ratioa

From: ABO and RhD blood group are not associated with mortality and morbidity in critically ill patients; a multicentre observational study of 29 512 patients

 

SAPS3, EMRb

ABO or RhD blood group

A

B

AB

RhD positive

Mortality

 28–day mortality

1.05–1.05*

0.93–1.07

0.87–1.08

0.91–1.23

0.94–1.11

 90–day mortality

1.04–1.05*

0.95–1.08

0.88–1.07

0.94–1.25

0.93–1.10

 Long-term mortalityc

1.02–1.02*

0.99–1.06

0.93–1.04

0.94–1.10

0.96–1.05

Morbidity

 DAFventd

1.05–1.05*

0.99–1.12

0.94–1.13

0.93–1.21

0.97–1.13

 DAFcirce

1.04–1.04*

0.92–1.03

0.95–1.15

0.97–1.27

0.93–1.08

 SOFA-maxf

1.06–1.07*

0.95–1.09

0.94–1.15

0.93–1.24

0.91–1.07

 Length-of-stay

1.01–1.01*

0.96–1.06

0.98–1.15

0.97–1.23

0.96–1.09

  1. aAll analyses were corrected for age and sex. All outcomes were analysed in separate multivariable regression models resulting in odds or hazard ratio for each ABO blood group and RhD status using blood group O and RhD negative as references
  2. bSimplified Acute Physiology Score 3 with estimated mortality risk
  3. cCox regression
  4. dDays alive and free of invasive ventilation
  5. eDays alive and free of circulatory support
  6. fMaximum of Sequential Organ Failure Assessment score during the ICU stay
  7. * P < 0.05