Timepoint 1 | Timepoint 2 | Timepoint 3 | ||||||
---|---|---|---|---|---|---|---|---|
SUB | CONV | SUB | CONV | p | SUB | CONV | p | |
pH | 7.46 [7.43;7.48] | 7.43 [7.40;7.46] | 7.36 [7.33;7.40] a | 7.36 [7.33;7.39] a | 0.806 | 7.29 [7.26;7.31] a,b | 7.30 [7.27;7.33] a,b | 0.675 |
paO2/ FiO2 [kPa] | 41 (35;47) | 36 (30;42) | 56 (50;63) | 56 (50;62) | 0.828 | 54 (48;60) | 53 (47;59) | 0.822 |
paCO2 [kPa] | 5.0 [4.4;5.6] | 5.4 [4.7;6.0] | 6.3 [5.7;6.9]a | 6.9 [6.2;7.5]a | 0.216 | 8.0 [7.4;8.6]a,b | 8.1 [7.4;8.7]a,b | 0.925 |
SaO2 [%] | 95 [92;98] | 95 [92;98] | 100 [96;103] | 100 [96;103] | 0.990 | 96 [93;99] | 100 [96–103] | 0.104 |
Peak [hPa] | 20 [17;23] | 22 [19;25] | 22 [19;25] | 24 [21;27] | 0.223 | 24 [21;27] a | 25 [22;28] | 0.572 |
PEEP [hPa] | 7 [6;7] | 8 [7;9] | 7 [6;8] | 8 [7;9] | 0.032 | 7 [6;7] | 8 [8;9] | 0.019 |
etCO2 [kPa] | 4.3 [3.9;4.8] | 4.3 [3.9;4.8] | 4.7 [4.3;5.1] | 4.8 [4.4;5.3] | 0.722 | 5.4 [4.9;5.9] a,b | 5.3 [4.8;5.7] a | 0.660 |
Vt [ml] | 454 [369;539] | 516 [432;601] | 385 [300;470] | 413 [328;497] | 0.646 | 427 [342;512] | 412 [327;497] | 0.800 |
MV [l*min−1] | 10.1 [8.7;11.6] | 9.8 [8.4;11.3] | 7.4 [5.9;8.8] a | 7.6 [6.2;9.0] a | 0.805 | 8.4 [6.9;9.8] | 7.6 [6.1;9.0] a | 0.406 |
C [ml*hPa−1] | 52 [43;60] | 45 [36;54] | 39 [30;48] a | 39 [31;48] | 0.971 | 38 [29;47] a | 43 [34;51] | 0.430 |
RR [min−1] | 22 [19;24] | 21 [19;24] | 19 [17;21] a | 19 [17;21] a | 0.912 | 21 [18;23] | 19 [17;21] a | 0.306 |
SpO2 [%] | 95 [91;99] | 94 [91;98] | 100 [99;107] a | 99 [95;102] | 0.086 | 99 [95;103] | 99 [96;103] | 0.947 |