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Table 1 Population characteristics

From: The impact of iron store on red blood cell transfusion: a multicentre prospective cohort study in cardiac surgery

 

Population (n = 502)

Patients with iron deficiency (n = 186)

Patients with RBC transfusion (n = 141)

Patients characteristics

  Age (years)a

67 ± 11 || 69(61–76)

67 ± 12 || 69(61–76)

69 ± 11|| 70 (64–77)

  Sex (male)b

364 (73%)

108 (58%)

75 (53%)

  BMI (kg m−2)a

27 ± 4 || 26(24–29)

27 ± 5 || 26(24–30)

28 ± 4 || 26 (23–29)

  SAPS IIa

28 ± 10 || 27(21–33)

28 ± 10 || 27(21–33)

31 (25–37)

ASA scoreb

  I

1 (0%)

1 (1%)

0

  II

7 (1%)

2 (1%)

1 (1%)

  III

435 (87%)

160 (86%)

117 (83%)

  IV

59 (12%)

23 (12%)

23 (16%)

  Smokingb

227 (45%)

73 (39%)

56 (40%)

  Hypertensionb

317 (63%)

121 (65%)

99 (70%)

  Dyslipidaemiab

234 (47%)

83 (45%)

63 (45%)

  Arteritisb

46 (9%)

23 (12%)

17 (12%)

  Anginab

155 (31%)

51 (27%)

41 (29%)

  Obstructive lung diseaseb

58 (12%)

26 (14%)

11 (8%)

  Diabetesb

96 (19%)

44 (23%)

25 (18%)

  CRFb

63 (13%)

24 (13%)

25 (18%)

  Serum creatinine (μmol l−1)a

88 ± 27 || 83(72–96)

83 ± 24 || 80(65–96)

83 ± 27 || 80 (67–103)

  Atrial fibrillationb

59 (12%)

25 (13%)

21 (15%)

NYHA classb

  1

95 (19%)

27 (14%)

19 (13%)

  2

289 (58%)

110 (59%)

76 (54%)

  3

111 (22%)

46 (25%)

44 (31%)

  4

7 (1%)

3 (2%)

3 (2%)

  LVEF (%)a

59 ± 11 || 60(55–66)

59 ± 12 || 60(55–66)

60 ± 11 || 59 (50–65)

  Pulmonary hypertensionb

62 (12%)

21 (11%)

24 (17%)

  Active antiplatelet therapyb

271 (54%)

92 (49%)

79 (56%)

Pre-operative biological data

  Pre-operative Hb (g dl−1)a

14 ± 4 || 14 [13,14,15]

14 ± 5 || 14 [13,14,15]

13 ± 4 || 13 (12–14]

  Pre-operative anaemiab

79 (16%)

16 (29%)

33 (28%)

  Serum ferritin (ng ml−1)a

191 ± 256 || 190 (93–316)

49 ± 26 || 70 [42–105]

191 ± 331 || 190 (95–308)

  Transferrin saturation (%)a

25 ± 13 || 25 (19–33)

16 ± 5 || 18 [15–26]

22 ± 13 || 23 (18–29)

  Iron Deficiency

198 (38%)

-

61 (43%)

Surgery characteristics

  Urgency of surgeryb c

    Elective

451 (90%)

168 (90%)

121 (86%)

    Urgent

51 (10%)

18 (10%)

20 (14%)

  Surgeryb

    Isolated Valve

186 (37%)

70 (38%)

48 (40%)

    Coronary bypass

208 (41%)

71 (38%)

50 (35%)

    Combined surgeryd

83 (17%)

36 (19%)

32 (24%)

    Aortic surgery

20 (4%)

6 (3%)

11 (8%)

    Other

5 (1%)

3 (2%)

0

    Reoperationb

14 (3%)

6 (3%)

8 (6%)

  1. ASA American Society of Anesthesiologists, BMI body mass index, CPB cardiopulmonary bypass, CRF chronic renal failure defined by a glomerular filtration rate < 60 ml min−1 1.73 m−2, Hb haemoglobin, LVEF left ventricular ejection fraction, NYHA New York Heart Association classification for dyspnoea, RBC red blood cells, SAPS II Simplified Acute Physiology Score 2
  2. aMean ± standard deviation || median (Q1-Q3) bNumber of patients (percentage)
  3. cUrgency of surgery according to the EuroSCORE II definitions. www.euroscore.org
  4. dCombined surgery: surgery combining valve and coronary bypass