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Fig. 4 | BMC Anesthesiology

Fig. 4

From: Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study

Fig. 4

Dexmedetomidine altered CSF metabolome in SAH patients. A Overview of CSF metabolome in dexmedetomidine and control groups: 2-dimension score plot. 0, control; 1; dexmedetomidine; Component 1 and 2, dimensions of the PLS-DA model. Pathway analysis (B) and metabolite set enrichment analysis (C) presented the most influenced metabolic pathway by dexmedetomidine. Significantly altered metabolites were listed in (D), left column: control; right column: dexmedetomidine; red arrow: trend; *: statistical significance. E CSF biomarker of dexmedetomidine sedation, with ROC curve and cut-off value

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BMC Anesthesiology

ISSN: 1471-2253

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