Fig. 3From: Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort studyPropofol altered CSF metabolome in SAH patients. (A) Overview of CSF metabolome in propofol and control groups: 2-dimension score plot. 0, control; 1; propofol; Component 1 and 2, dimensions of the PLS-DA model. Pathway analysis (B) and metabolite set enrichment analysis (C) presented the most influenced metabolic pathway by propofol. Significantly altered metabolites were listed in (D), left column: control; right column: propofol; red arrow: trend; *: statistical significance. E CSF biomarker of propofol sedation, with ROC curve and cut-off valueBack to article page