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Table 3 Comparison between the PLACEBO and EMLA NaCl groups. VAS scores (mm) presented as mean and standard deviation (+SD) at each time-point

From: Effect of topical local anaesthesia on injection pain associated with administration of sterile water injections - a randomized controlled trial

 

PLACEBO NaCl

EMLA NaCl

 

Time-points

Mean (+SD)

Mean (+SD)

p-value

1–3 s

34.0 (21,7)

6.0 (8,5)

0.000

30 s

18.6 (19,0)

6.0 (8,9)

0.000

1 min

14.0 (16,7)

2.8 (4,6)

0.000

2 min

10.6 (15,8)

2.4 (4,1)

0.008

3 min

6.17 (8,3)

1.8 (3,3)

0.005

4 min

3.8 (5,0)

1.3 (2,1)

0.028

5 min

2.0 (2,5)

1.3 (2,1)

0.116

10 min

1.3 (1,8)

1.8 (3,4)

0.916

15 min

1.4 (1,8)

2.5 (7,3)

0.236

  1. EMLA Patch with local anesthesia, NaCl Isotonic saline (0.9%)