Variables | T0 | T1 | T2 | T3 | T4 | P Value T0 versus T1 | P Value T1 versus T2 | P Value T3 versus T4 |
---|---|---|---|---|---|---|---|---|
HR (bpm) | ||||||||
 Responders | 69 ± 12 | 68 ± 13 | 67 ± 13 | 69 ± 15 | 68 ± 14 | 0.428 | 0.732 | 0.231 |
 Nonresponders | 67 ± 10 | 66 ± 10 | 63 ± 10 | 66 ± 10 | 66 ± 9 | 0.496 | 0.010* | 0.744 |
MAP (mmHg) | ||||||||
 Responders | 77 ± 13 | 77 ± 12 | 58 ± 13 | 74 ± 12 | 80 ± 12 | 0.801 | <  0.001* | 0.031* |
 Nonresponders | 78 ± 9 | 78 ± 9 | 66 ± 13 | 78 ± 8 | 78 ± 8 | 0.231 | <  0.001* | 0.859 |
Stroke volume (mL) | ||||||||
 Responders | 62 ± 14 | 59 ± 14 | 26 ± 21 | 56 ± 14 | 67 ± 15 | 0.002* | <  0.001* | <  0.001* |
 Nonresponders | 59 ± 11 | 58 ± 11 | 39 ± 17 | 58 ± 11 | 60 ± 11 | 0.009* | <  0.001* | 0.002* |
SVV (%) | ||||||||
  Responders | 10 ± 3 | 12 ± 4 |  | 12 ± 4 | 10 ± 2 | 0.005* |  | 0.047* |
  Nonresponders | 12 ± 4 | 13 ± 6 |  | 13 ± 5 | 12 ± 5 | 0.046* |  | 0.067 |
PPV (%) | ||||||||
  Responders | 9 ± 3 | 10 ± 4 |  | 10 ± 5 | 9 ± 3 | 0.015* |  | 0.057 |
  Nonresponders | 10 ± 6 | 11 ± 6 |  | 11 ± 5 | 9 ± 5 | 0.037* |  | 0.008* |