Skip to main content

Table 1 The preoperative demographic data and general perioperative characteristics of patients undergoing hepatectomy

From: Factors affecting sufentanil consumption for intravenous controlled analgesia after hepatectomy: retrospective analysis

 

All (n = 562)

PCA-NH (n = 428)

PCA-H (n = 134)

P-value

Median (IQR)

n (%)

Median (IQR)

n (%)

Median (IQR)

Age (years old)

57.00 (48.00, 65.00)

 

59.00 (49.00, 65.00)

 

53.78 (44.83, 61.58)

0.002*

Gender

 Male

 

230 (72.8)

 

86 (27.2)

 

0.034*

 Female

 

198 (80.5)

 

48 (19.5)

  

BMI (kg/m2)

22.7 (20.8, 22.3)

 

22.60 (20.67, 25.16)

 

23.35 (21.22, 25.30)

0.307

Intraoperative blood loss (ml)

200 (100, 500)

 

200.00 (100.00, 500.00)

 

292.31 (141.67, 714.29)

0.001*

Operative time (min)

210 (160, 300)

 

205 (156.25, 285.00)

 

245.38 (182.08, 320.00)

0.002*

Intraoperative transfusion

 No

 

289 (79.4)

 

75 (20.6)

 

0.015*

 Yes

 

139 (70.2)

 

59 (29.8)

  

RBC (u)

0 (0, 2.00)

 

0 (0, 1.50)

 

0.73 (0, 2.11)

0.164

FFP (ml)

0 (0, 352.50)

 

0 (0, 315.00)

 

1.42 (0, 385.71)

0.034*

Extent of resection

 Minor hepatic resection

 

246 (90.4)

 

26 (9.6)

 

< 0.001*

 Major hepatic resection

 

182 (62.8)

 

108 (37.2)

  

Surgical approach

 Laparoscope

 

251 (83.1)

 

51 (16.9)

 

< 0.001*

 Open

 

177 (68.1)

 

83 (31.9)

  

ASA classification

 I + II

 

386 (76.3)

 

120 (23.7)

 

0.831

 III

 

42 (75.0)

 

14 (25.0)

  

Introperative DEX

 No

 

52 (77.6)

 

15 (22.4)

 

0.766

 Yes

 

376 (76.0)

 

119 (24.0)

  

Postoperative NSAIDs

 No

 

301 (76.8)

 

91 (23.2)

 

0.595

 Yes

 

127 (74.7)

 

43 (25.3)

  

PONV

 No

 

404 (77.0)

 

121 (23.0)

 

0.095

 Yes

 

24 (64.9)

 

13 (35.1)

  

Resting pain score on POD1

2 (0, 3)

 

2 (0.25, 3)

 

2 (0,3)

0.251

Movement pain score on POD1

5 (4, 6)

 

5 (4, 6)

 

5 (5,6)

0.503

Resting pain score on POD2

1 (0, 2)

 

1 (0,2)

 

1 (0,2)

0.823

Movement pain score on POD2

3 (3, 4)

 

3 (3,4)

 

4 (3,4)

0.056

Sufentanil dosage 24 h (μg)

50 (34, 75)

 

42.00 (31.00, 56.75)

 

98.00 (80.00,118.00)

< 0.001*

Sufentanil dosage 48 h (μg)

91 (64, 133)

 

77.00 (60.00, 101.75)

 

173.00 (149.75, 205.75)

< 0.001*

  1. *P value < 0.05 statistically significant, whether it is a high PCA sufentanil dose comparison between the two groups; Mann-Whitney U test; Chi-square test; n(%) = number (percentage); PCA-H High PCA sufentanil dosage, PCA-NH Non high PCA sufentanil dosage, DEX Dexmedetomidine, NSAIDs Anti-inflammatory and analgesic drugs, RBC (u) Intraoperative transfusion of red blood cells (unit), FFP (ml) Intraoperative transfusion of fresh frozen plasma (ml), POD1 Postoperative first day, POD2 Postoperative second day