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Table 5 Predictors of AKI

From: Prevalence and risk factors of myocardial and acute kidney injury following radical nephrectomy with vena cava thrombectomy: a retrospective cohort study

 

Univariable analysis a

Multivariable analysis b

OR (95% CI)

P value

OR (95% CI)

P value

Age, year c

1.01 (0.98, 1.04)

0.431

–

–

Body mass index, kg/ m2

1.12 (1.01, 1.23)

0.029

1.18 (1.06, 1.33)

0.004

Previous stroke

3.57 (0.67, 19.07)

0.136

–

–

Previous surgery

0.46 (0.18, 1.19)

0.108

–

–

Mayo classification c

 I + II

Ref

–

–

–

 III + IV

1.61 (0.80, 3.26)

0.186

–

–

Interval from contrast-enhanced examination, day

1.02 (0.99, 1.05)

0.144

–

–

Selective renal arterial embolization

0.40 (0.16, 1.02)

0.056

0.20 (0.07, 0.59)

0.004

Use of sevoflurane during anesthesia

1.65 (0.84, 3.25)

0.145

–

–

Use of dexmedetomidine during anesthesia

0.63 (0.32, 1.23)

0.176

–

–

Acute normovolemic hemodilution before surgery

1.58 (0.79, 3.17)

0.194

–

–

Duration of intraoperative hypotension, 20 min

1.27 (1.04, 1.54)

0.021

1.30 (1.04, 1.64)

0.024

Occurrence of intraoperative tachycardia

1.87 (0.93, 3.77)

0.081

–

–

Transfusion of platelet concentrate

2.42 (0.97, 6.03)

0.059

–

–

Use of PCA after surgery

5.60 (0.67, 46.78)

0.112

–

–

  1. Highest lactic acid during surgery was excluded because of correlation with duration of hypotension
  2. a Acute kidney injury was modeled as a function of a single factor in the univariable logistic regression analysis
  3. b Acute kidney injury was modeled as a function of all factors with a P value < 0.2 in the univariate analyses or those that were considered clinically important. Multivariable analysis was performed using the backward method. Hosmer-Lemeshow test of goodness of fit of the model: χ2 = 4.612, df = 8, P = 0.798
  4. c Included because of clinical importance