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Table 3 Postoperative outcomes

From: Prevalence and risk factors of myocardial and acute kidney injury following radical nephrectomy with vena cava thrombectomy: a retrospective cohort study

 

Non-myocardial injury (n = 89)

Myocardial injury (n = 54)

P value

Non-AKI (n = 82)

AKI (n = 61)

P value

Highest cTnI (ng/ml), median (95%CI)

0.010 (0.003, 0.010)

0.790 (0.067, 2.272)

< 0.001

0.010 (0.003, 0.038)

0.040 (0.010, 1.100)

0.004

Development of myocardial injury

0 (0%)

54 (100.0%)

–

23 (28.0%)

31 (50.8%)

0.005

 Acute myocardial infarction a

0 (0%)

11 (20.4%)

< 0.001

3 (3.7%)

8 (13.1%)

0.036

Highest creatinine (μmol/L)

113.0 (98.4, 129.4)

125.0 (99.0, 146.3)

0.152

106.5 (92.0, 123.3)

129.6 (116.1, 160.7)

< 0.001

Development of AKI

30 (33.7%)

31 (57.4%)

0.005

0 (0.0%)

61 (100.0%)

–

Stage of AKI

  

0.014

  

–

 Stage 1

26 (29.2%)

27 (50.0%)

 

0 (0.0%)

53 (86.9%)

 

 Stage 2

2 (2.2%)

4 (7.4%)

 

0 (0.0%)

6 (9.8%)

 

 Stage 3

2 (2.2%)

0 (0.0%)

 

0 (0.0%)

2 (3.3%)

 

Requirement of RRT

1 (1.1%)

0 (0.0%)

> 0.999

0 (0.0%)

1 (1.6%)

0.427

ICU admission

57 (64.0%)

51 (94.4%)

< 0.001

59 (72.0%)

49 (80.3%)

0.249

 With endotracheal intubation

44 (49.4%)

49 (90.7%)

< 0.001

53 (64.6%)

40 (65.6%)

0.907

 Mechanical ventilation, h

0 (0, 0)

11 (8, 14)

< 0.001

4 (2, 6)

5 (3, 7)

0.247

 Length of stay in ICU, h

14 (12, 16)

46 (29, 63)

< 0.001

20 (17, 23)

36 (19, 53)

0.046

Other complications

1 (1.1%)

13 (24.1%)

0.001

2 (2.4%)

12 (19.7%)

0.005

 New onset arrhythmia b

0 (0.0%)

6 (11.1%)

0.005

1 (1.2%)

5 (8.2%)

0.102

 Pulmonary embolism c

0 (0.0%)

2 (3.7%)

0.141

0 (0.0%)

2 (3.3%)

0.180

 Pulmonary infection d

1 (1.1%)

4 (7.4%)

0.130

1 (1.2%)

4 (6.6%)

0.208

 Wound infection e

0 (0%)

1 (1.9%)

0.378

0 (0.0%)

1 (1.6%)

0.427

Length of hospital stay, day

7 (6, 7)

13 (12, 14)

< 0.001

8 (7, 9)

10 (7, 13)

0.027

In-hospital mortality

0 (0%)

0 (0%)

–

0 (0%)

0 (0%)

–

  1. Data are median (interquartile range), number (%), or median (95% CI). P values in bold indicate < 0.05
  2. AKI acute kidney injury (diagnosed according to KDIGO criteria), RRT renal replacement therapy, ICU intension care unit
  3. a Acute myocardial infarction refers to dynamic elevations of cardiac troponin in combination with either ischemic symptoms, electrocardiogram changes, or imaging findings
  4. b New onset arrhythmia refers to new
  5. -onset atrial fibrillation or paroxysmal supraventricular tachycardia necessitating medical treatment
  6. c Pulmonary embolism confirmed by computed tomography pulmonary angiography
  7. d New infiltrate on chest radiograph with hyperthermia (> 38.3 °C) and leukocytosis (≥12,000/mm3) and required intravenous antibiotic therapy
  8. e Wound infection refers to pus expressed from the incision and bacteria cultured from the pus