Table 1 The comparison of patients’ characteristics, delta HR, delta MAP, delta E, and delta NE among three groups. The data of 2 cases that were withdrawn from group R2 were not included in this table. Values are presented as mean ± SD or n. The baseline value of each parameter was the average value measured 3 and 1 min before CO2 pneumoperitoneum. The value of delta represents the difference between before and after pneumoperitoneum stimulation. HR, heart rate; MAP, mean arterial pressure; E, epinephrine concentration; NE, norepinephrine concentration. #P < 0.05, compared with group R0; * P < 0.05, compared with group R1
Parameter | Group R0 | Group R1 | Group R2 | P values | |||
|---|---|---|---|---|---|---|---|
R0&R1&R2 | R0&R1 | R0&R2 | R1&R2 | ||||
Age (years) | 4.6 ± 1.0 | 5.5 ± 1.1 | 4.9 ± 1.0 | 0.147 | 0.055 | 0.553 | 0.156 |
Body weight (kg) | 17.1 ± 2.5 | 18.3 ± 2.2 | 17.5 ± 2.1 | 0.359 | 0.188 | 0.901 | 0.222 |
Male/Female (n) | 16/2 | 12/1 | 16/3 | 0.912 | 0.802 | 0.968 | 0.833 |
MACBAR (%) | 3.29 ± 0.17 | 2.12 ± 0.10# | 1.29 ± 0.11#* | 0.000 | 0.000 | 0.000 | 0.000 |
Baseline HR (bpm) | 135 ± 13 | 106 ± 15 # | 94 ± 11 # | 0.000 | 0.000 | 0.000 | 0.026 |
Delta HR | 9 ± 12 | 7 ± 13 | 8 ± 5 | 0.863 | 0.595 | 0.732 | 0.849 |
Baseline MAP (mmHg) | 68 ± 5 | 59 ± 2 # | 54 ± 6 # | 0.000 | 0.000 | 0.000 | 0.013 |
Delta MAP | 8 ± 6 | 11 ± 10 | 13 ± 9 | 0.344 | 0.362 | 0.151 | 0.589 |
Baseline E (ngml-1) | 2.20 ± 0.63 | 2.10 ± 0.80 | 2.05 ± 0.91 | 0.900 | 0.764 | 0.655 | 0.883 |
Delta E | 0.20 ± 1.23 | 0.33 ± 0.95 | -0.06 ± 1.21 | 0.693 | 0.787 | 0.572 | 0.405 |
Baseline NE (pgml-1) | 540.30 ± 65.64 | 498.40 ± 61.66 | 464.09 ± 76.91 | 0.373 | 0.453 | 0.164 | 0.510 |
Delta NE | 65.31 ± 20.75 | 56.24 ± 21.01 | 52.85 ± 24.37 | 0.368 | 0.297 | 0.181 | 0.706 |